Welcome to Digital Discovery!
We are delighted to welcome Professor Jason E. Hein, University of British Columbia, Canada, as a new member of the Editorial Board of Digital Discovery.
“The fusion between advanced automation, machine learning and chemical synthesis is rapidly expanding the boundaries of our understanding. This interdisciplinary ecosystem is helping researchers explore further, challenge experimental biases and in my opinion, represents one of the most exciting opportunities imaginable.”
Jason Hein received his BSc in Biochemistry in 2000 and PhD in asymmetric reaction methodology in 2005 from the University of Manitoba (NSERC PGS-A/B, Prof. Philip G. Hultin). In 2006, he became an NSERC postdoctoral research fellow with Professor K. Barry Sharpless and Professor. Valery V. Fokin at the Scripps Research Institute in La Jolla, CA. In 2010, he became a senior research associate with Professor Donna G. Blackmond at the Scripps Research Institute. He began his independent career at the University of California, Merced in 2011, employing in-situ kinetic reaction analysis to rapidly profile and study complex networks of reactions. In 2015, he moved to the University of British Columbia to continue the development of automated reaction analytical technology to serve mechanistic organic chemistry. His research has resulted in a collection of prototype modular robotic tools and integrated analytical hardware which create the first broadly applicable automated reaction profiling toolkit geared toward enabling autonomous research and discovery. He was the co-lead of Project ADA; the world’s first autonomous discovery platform for thin film materials, supported by Natural Resources Canada, co-PI of the MADNESS team supported by the DARPA Accelerated Molecular Discovery Program and an Associate Director of the Acceleration Consortium spearheaded by the University of Toronto.
Read some of Jason’s recent papers below.
A robust new tool for online solution-phase sampling of crystallizations
Andrew J. Kukor, Mason A. Guy, Joel M. Hawkins and Jason E. Hein
React. Chem. Eng., 2021, DOI: 10.1039/D1RE00284H
Data-Science Driven Autonomous Process Optimization
Melodie Christensen, Lars P. E. Yunker, Folarin Adedeji, Florian Häse, Loïc M. Roch, Tobias Gensch, Gabriel dos Passos Gomes, Tara Zepel, Matthew S. Sigman, Alán Aspuru-Guzik and Jason E. Hein
Commun. Chem., 2021, 4, 112.
Automated Solubility Screening Platform Using Computer Vision
Parisa Shiri, Veronica Lai, Tara Zepel, Daniel Griffin, Jonathan Reifman, Sean Clark, Shad Grunert, Lars P.E. Yunker, Sebastian Steiner, Henry Situ, Fan Yang, Paloma L. Prieto and Jason E. Hein
iScience, 2021, 24, 102176
Real-Time HPLC-MS Reaction Progress Monitoring Using an Automated Analytical Platform
Thomas C. Malig, Josh D. B. Koenig, Henry Situ, Navneet K. Chehal, Philip G. Hultin and Jason E. Hein
React. Chem. Eng., 2017, 2, 309–314.
Please join us in welcoming Professor Hein to Digital Discovery.