The RSC Chemical Biology “Editor’s choice” article collection
The new ‘Editor’s choice’ collection for RSC Chemical Biology celebrates the very best work published in the journal to date, including regularly added articles personally chosen by our world-renowned Editorial Board, as well as those highlighted as “HOT” during the peer review process.
|This month, Associate Editor Cai-Guang Yang has highlighted three of his favourite articles to date.
Below are his choices. Access the full collection for free.
Labelling of DNA and RNA in the cellular environment by means of bioorthogonal cycloaddition chemistry
Dorothée Ganz, Dennis Harijan and Hans-Achim Wagenknecht
RSC Chem. Biol., 2020, 1, 86-97
Professor Yang, “This review summarizes DNA and RNA labelling by means of bioorthogonal cycloaddition chemistry in the cellular environment. It also describes current status of orthogonal dual and triple labelling of DNA and RNA in vitro to demonstrate the potential in vivo applications for future.”
Macrocyclic peptides that inhibit Wnt signalling via interaction with Wnt3a
Manuel E. Otero-Ramirez, Kyoko Matoba, Emiko Mihara, Toby Passioura, Junichi Takagi and Hiroaki Suga
RSC Chem. Biol., 2020, 1, 26-34
Professor Yang, “By applying a unique RaPID display screening technique, this work reports the first instance of de novo macrocyclic peptides acting as direct binders of a highly hydrophobic and not commonly targeted Wnt protein or similar unstable proteins.”
A live-cell assay for the detection of pre-microRNA–protein interactions
Sydney L. Rosenblum, Daniel A. Lorenz and Amanda L. Garner
RSC Chem. Biol., 2021, 2, 241-247
Professor Yang, “This work reports the efforts in the development of a new approach for detection of RNA–protein interactions (RPIs), RNA interaction with Protein- mediated Complementation Assay (RiPCA). RiPCA could serve as a useful tool for detecting RPIs in live cells.”
|February saw Associate Editor Seung-Bum Park has added his choice to the collection.
Below is Professor Park’s choice. Access the full collection for free.
In vivo delivery of a fluorescent FPR2/ALX-targeted probe using focused ultrasound and microbubbles to image activated microglia
Sophie V. Morse, Tamara Boltersdorf, Tiffany G. Chan, Felicity N. E. Gavins, James J. Choi and Nicholas J. Long
RSC Chem. Biol., 2020, 1, 385-389
|In January we launched the collection with 3 papers chosen by our Editorial Chair, Professor Hiroaki Suga, alongside some of our hottest papers published in 2020.
Below are Professor Suga’s choices. Access the full collection for free.
The chemical biology of coronavirus host–cell interactions
Suprama Datta, Erik C. Hett, Kalpit A. Vora, Daria J. Hazuda, Rob C. Oslund, Olugbeminiyi O. Fadeyi and Andrew Emili
RSC Chem. Biol., 2021, Advance Article
Professor Suga, “This review timely and complehensively summarizes the biological events linked to the coronavirus outbreak.”
A thorough analysis and categorization of bacterial interrupted adenylation domains, including previously unidentified families
Taylor A. Lundy, Shogo Mori and Sylvie Garneau-Tsodikova
RSC Chem. Biol., 2020, 1, 233-250
Professor Suga, “The families of interrupted A domains and types of M domains in nonribosomal peptide class of natural products have been categorized. It has illuminated patterns and insights on how to harness them for engineering studies in the future.”
Harnessing the PD-L1 interface peptide for positron emission tomography imaging of the PD-1 immune checkpoint
Kuan Hu, Lin Xie, Masayuki Hanyu, Yiding Zhang, Lingyun Li, Xiaohui Ma, Kotaro Nagatsu, Hisashi Suzuki, Weizhi Wang and Ming-Rong Zhang
RSC Chem. Biol., 2020, 1, 214-224
Professor Suga, “Authors of this paper have developed an impressive PET imaging tool for the most famous immune check point mediated by the PD-1 and PD-L1 interaction, demonstrating not only cell culture and ex vivo detection but also in vivo detection in mice.”
We hope you enjoy reading these articles!