Now Published in the RSC Drug Discovery Series
New Horizons in Predictive Toxicology: Current Status and Application
Edited by Alan G.E. Wilson
The sophistication of modelling and simulation technologies have improved dramatically over the past decade and their application in toxicity prediction and risk assessment are of critical importance. The integration of predictive toxicology approaches will become increasingly important as industrial chemicals advance and change and as new pharmaceuticals enter the market.
In this comprehensive discussion of predictive toxicology and its applications, leading experts express their views on the technologies currently available and the potential for future developments. The book covers a wide range of topics including in silico, in vitro andin vivo approaches that are currently being used in the safety assessment of chemical substances. It reflects the growing and urgent need to strengthen and improve our ability to predict the safety and risks posed by industrial and pharmaceutical chemicals in humans. The reader will find extensive information on the use of current animal models, including genetically-modified ones and target-mediated toxicities, for various toxicities. Also discussed are the recent regulatory initiatives, to improve safety assessment of pharmaceutical and industrial chemicals.
The book provides an expert and comprehensive discussion on the current status and future directions of predictive toxicology and its application in the life science industries.
http://www.rsc.org/shop/books/2011/9781849730518.asp
