Biomaterials Science Emerging Investigator- Vincent Venditto

Dr. Vincent J. Venditto received training in organic synthesis and vaccine development. He obtained a BS in chemistry from Gettysburg College and then worked for two years at the NCI, NIH as a cancer research trainee before attending graduate school. He obtained a PhD in chemistry from Texas A&M University and worked on vaccine development as an NIH postdoctoral fellow at University of California, San Francisco.

Students and fellows in his lab come from diverse backgrounds with interests in chemistry, biology, drug delivery and experimental therapeutics, but a common goal of exploring novel methods to modulate the immune system. Students and fellows in his lab are encouraged to utilize their skills to advance projects while learning new skills to better appreciate the various aspects of designing novel immunotherapies.

You can find out more about Vincent and his research on his webpage

Follow Vincent on Twitter @vjvenditto

Read Vincent’s Emerging Investigator article, ‘In vivo assessment of triazine lipid nanoparticles as transfection agents for plasmid DNA’, DOI: 10.1039/D2BM01289H

Check out our interview with Vincent below:

1. How do you feel about Biomaterials Science as a place to publish research on this topic?

Biomaterials science is a great journal to publish novel lipids for gene delivery. The interdisciplinary nature of our work is highlighted by the broad readership of Biomaterials Science.

2. What aspect of your work are you most excited about at the moment and what do you find most challenging about your research?

The lipids presented in the manuscript demonstrate in vitro and in vivo transfection efficiency, and importantly demonstrates a platform for continued iterative development of novel lipids for improved nucleic acid delivery.

3. In your opinion, what are the most important questions to be asked/answered in this field of research?

How do we improve upon the success achieved with the COVID-19 vaccines?

4. Can you share one piece of career-related advice or wisdom with other early career scientists?

Do what excites you.

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Biomaterials Science 10th Anniversary Reviewer Spotlight- Honggang Cui

Biomaterials Science is delighted to recognise our outstanding reviewers for their support and significant contributions to the journal. As part of the 10th Anniversary celebrations, we are highlighting some of our most loyal reviewers in a ‘Reviewer Spotlight’ series. We are grateful to all our reviewers and appreciate the dedication and support they give to the journal.

Honggang Cui is a Biomaterials Science reviewer and has received an outstanding reviewer award for his contributions to the journal in 2020. Find out more about Honggang below and read his interview with advice for reviewers for the journal.

 

Honggang Cui is an associate professor of chemical and biomolecular engineering at The John Hopkins University with a joint appointment in the Department of Materials Science and Engineering.  Dr. Cui works on the development of supramolecular biomaterials and drug-based assemblies, with the goal of improving the current treatment and prevention of some important human diseases.

 

1. What do you like most about being a reviewer for Biomaterials Science?

The opportunity to learn something exciting and new. I also enjoy having the opportunity to help the authors improve the quality of their manuscript.

 

2. What would you recommend to new reviewers to ensure their report is helpful?

A manuscript cannot solve all the problems in the field. So long as a manuscript can teach us something new and important, it is a good manuscript worthy of sharing with the community. Questions raised should be centered on the key points that the authors tried to convey in their manuscript. Even if you recommend rejection, please explain your rationale and provide constructive suggestions as to how the manuscript can be further improved.

 

You can find out more about Honggang and his research on his webpage

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Biomaterials Science 10th Anniversary Reviewer Spotlight- Yongzhuo Huang

Biomaterials Science is delighted to recognise our outstanding reviewers for their support and significant contributions to the journal. As part of the 10th Anniversary celebrations, we are highlighting some of our most loyal reviewers in a ‘Reviewer Spotlight’ series. We are grateful to all our reviewers and appreciate the dedication and support they give to the journal.

Yongzhuo Huang is a Biomaterials Science reviewer and has received an outstanding reviewer award for his contributions to the journal in 2019. Find out more about Yongzhuo below and read his interview about his experiences of being a reviewer.

 

Yongzhuo Huang is currently a Professor of Pharmaceutics at the Shanghai Institute for Materia Medica at the Chinese Academy of Sciences. He received his Ph.D. from Zhejiang University and then conducted postdoctoral training at the University of Michigan College of Pharmacy. He focuses on application of drug delivery technology to explore the new therapeutic mechanisms and strategies in cancer and inflammation diseases. He is interested in targeted drug delivery, transdermal delivery, and protein delivery.

He has published over 150 articles, and supervised/co-supervised 50 graduates, 20 PhD students, and 8 postdoctoral researchers.

He is an editor of International Journal of Pharmaceutics, and serves in the advisory or editorial boards of Nano Letters, Journal Controlled Release, Acta Pharmaceutica Sinica B, Cancer Biology & Medicine and Medicine in Drug Discovery. He has also served as a Guest Editor for various theme issues, including the issue of “Biomimetic Therapeutics” in Biomaterials Science (2019). He is an active reviewer for over 120 scientific journals.

 

1. What encouraged you to become a reviewer for Biomaterials Science?

Biomaterials Science is a well-respected journal covering multidisciplinary areas. I like to keep myself posted on the up-to-date cutting-edge research to be published in the journal. Moreover, I have authored a number of articles in BM, and thanks to the excellent reviewers, their valuable comments did help me a lot improve the quality of the articles. As a way to give back, I am more than happy to serve as a reviewer for BM. 

 

2. What would you recommend to new reviewers to ensure their report is helpful?

When I review a manuscript, I often ask myself what I will do if I am going to conduct a similar study. I will compare the plan conceived in my mind with the work in the manuscript and try to find out the pros and cons. Originality and solidness is two essential criteria to evaluate a manuscript. If a reviewer can provide a detailed analysis of originality of the work and solidness of the experiments will be helpful for the authors to improve their work and for the editors to make a decision. Please treat a manuscript in a way what you want yours to be treated.

 

3. Has being a reviewer affected how you approach the preparation of your recent manuscripts?

Yes. I do learn a lot from being a reviewer. When a manuscript leaves me a deep impression, I would try to find out which elements stick in my mind. From a critical reading of a manuscript, I can appreciate the well-organized structure, clear presentation, and the way to prepare the beautiful schemes and figures. Such experience will affect my manuscript-writing, in various aspects.

 

You can find out more about Yongzhuo and his research on his webpage.

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Biomaterials Science 10th Anniversary Reviewer Spotlight- Jiao Jiao Li

Biomaterials Science is delighted to recognise our outstanding reviewers for their support and significant contributions to the journal. As part of the 10th Anniversary celebrations, we are highlighting some of our most loyal reviewers in a ‘Reviewer Spotlight’ series. We are grateful to all our reviewers and appreciate the dedication and support they give to the journal.

Jiao Jiao Li is a Biomaterials Science reviewer and has received outstanding reviewer awards for her contributions to the journal in 2019, 2020 and 2021. Find out more about Jiao Jiao below and read her interview for advice for reviewers and authors publishing in the journal.

Dr Jiao Jiao Li is a biomedical engineer and medical scientist. Her research in tissue engineering and regenerative medicine aims to develop new therapies for chronic diseases, particularly for damaged bones and joints using a combination of approaches including stem cells, biomaterials, nanotechnology, and more. She is a Lecturer and Research Group Leader at University of Technology Sydney, a National Health and Medical Research Council Early Career Fellow, and Co-Deputy Director on the Australian Research Council Training Centre for Innovative BioEngineering. She was selected by Science & Technology Australia as a 2021-22 Superstar of STEM – one of 60 Australian women to serve as national role models for the community. Jiao Jiao has been recognised for her contributions to research and social impact, including in 2022 the NSW Young Tall Poppy Scientist of the Year for her nationally significant contributions to research excellence and science communication, and being named as Australia’s Top 20 Under 40 Researchers. She was also the Australian winner of the international Falling Walls Lab competition in 2021. Jiao Jiao has a passion for disseminating science in the community, and for raising up the next generation of secondary and tertiary students for their future careers and leadership in STEM.

 

1. What do you like most about being a reviewer for Biomaterials Science?

Biomaterials Science gets a lot of high quality submissions from the field. As someone who was initially trained as a biomaterials scientist, I love seeing the latest cutting-edge work going on in the field. I myself have learnt a lot from the papers I reviewed, many of which were from groups conducting the most innovative work in my interest area of tissue engineering. I also really appreciate the efficient and transparent peer review process. By looking at my own comments compared to those of other reviewers and the editor’s decision on manuscripts, I have learnt a lot about the peer review process and how to optimise the quality of my own manuscripts. Also, I think I have been reviewing for the journal for a good many years and it has almost grown up together with my academic career. I am proud to say that I have helped contribute to the growth of Biomaterials Science over the years as now a major outlet for high quality papers in the biomaterials field.

 

2. Do you have any advice for first-time authors seeking publication in BM?

I find that the best (original research) manuscripts all share some common characteristics: 1) the work conducted was innovative or gave some new insights into what was previously not known in the field, 2) the characterisations were done to good breadth and depth appropriate to the subject matter, and results taken together convincingly prove the conclusions, and 3) the manuscript was written in a way that demonstrates knowledge of the latest advances relating to the specific subject matter and explains the significance of the work to a possibly generalist scientific audience. Also, I find that the editors of the journal are very good at finding reviewers who have specific expertise in the topic area of the manuscript, so the manuscript needs to make sure that it well explains the specific novelty/significance of the work compared to the latest advances (e.g., why is this particular combination of fabrication process/materials composition/analysis techniques new or different from what has already been done?).

 

3. What would you recommend to new reviewers to ensure their report is helpful?

I think as a responsible reviewer, we should make a firm judgement about where we want the manuscript to go after the review. The best manuscripts clearly worthy of publishing should be recommended as such, but most of them are more difficult to judge. If it looks like a study that holds value for publishing in the journal but has significant room for improvement, then the report should have constructive feedback to say specifically how you expect the manuscript to be improved. This could be from both a writing perspective and from an experimental/analysis perspective. Usually if a manuscript is missing appropriate controls or the analysis was not performed correctly but the data is still worth publishing, it is not realistic to ask for new experiments to be performed but rather it is better to ask the authors to explicitly discuss these limitations in the revision. For manuscripts that clearly do not match the quality of the journal, constructive feedback should still be given to point out (politely) the critical flaws in a way that might help the authors (e.g., insufficient analyses were performed, or the study did not provide new insights compared to what has already been reported many times in the literature). Also, I find it unnecessary to scrutinise sentences for language expression unless there is a technical mistake as it is not our role as reviewers to write the manuscript for the authors, but that’s just me.

 

4. What has been your biggest learning point from reviewing and has this affected how you approach the preparation of your recent manuscripts?

I find that the shared comments from other anonymous reviewers have really helped me a lot in benchmarking my own reviews and improving the preparation of my own manuscripts. Reviewing for Biomaterials Science has accompanied the growth of my academic career from a postdoctoral scientist to now a research team leader. Seeing the comments of other reviewers on the same manuscript, many of whom were clearly experts in the topic area gave me confidence that my feelings were correct about a particular piece of work in the field. There were some rare instances where my comments differed a lot from those of others, which I took as a valuable learning experience to see what I had missed and to benchmark my expectations. Building up my reviewing experience with Biomaterials Science over the years has definitely helped me in preparing more scientifically sound and better communicated manuscripts. It has also helped me gain realistic expectations of how my manuscripts are likely to land with expert reviewers and to better appreciate differing opinions.

 

You can find out more about Jiao Jiao and her research on her webpage and follow her on Twitter @JiaoJiaoLi_Syd.

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Biomaterials Science 10th Anniversary Reviewer Spotlight- Nuria Oliva

Biomaterials Science is delighted to recognise our outstanding reviewers for their support and significant contributions to the journal. As part of the 10th Anniversary celebrations, we are highlighting some of our most loyal reviewers in a ‘Reviewer Spotlight’ series. We are grateful to all our reviewers and appreciate the dedication and support they give to the journal.

Nuria Oliva is a Biomaterials Science reviewer and received an outstanding reviewer award for her contributions to the journal in 2020. Find out more about Nuria below and read her interview for her tips and tricks for reviewers and authors publishing in the journal.

Dr. Nuria Oliva is an Assistant Professor and la Caixa Junior Leader Fellow at IQS Barcelona, and an Honorary Research Fellow at Imperial College London. Her group works at the intersection of biomaterials, biology and medicine to tackle complex human diseases like osteoarthritis, fibrosis or cancer. She graduated with a PhD in Medical Engineering and Medical Physics from the Harvard-MIT Division of Health Sciences and Technology, before becoming a postdoctoral fellow at Imperial College London. In 2020, Nuria started her independent group as an Imperial College Research Fellow.

 

1. What encouraged you to become a reviewer for Biomaterials Science?

I wanted to give back to the biomaterials community. I recognised that my previous work had been published thanks to the work of other experts in the field, and so I wanted to facilitate that for other scientists seeking to share their work.

2. Do you have any advice for first-time authors seeking publication in Biomaterials Science?

Less is more! Tell a compelling story that is backed up by your data, and only display the data that tells your story. All additional data can go to supplemental information. A compilation of massive amounts of data often distracts from getting the important, main message across.

3. What would you recommend to new reviewers to ensure their report is helpful?

Be objective, be fair and most importantly, provide details of any criticism. A vague review doesn’t help anyone involved in the process and generates more work for the editor, the authors, and yourself on the event of a second round of reviews.

4. Has being a reviewer affected how you approach the preparation of your recent manuscripts?

Absolutely. Having reviewed a fair amount of manuscripts by now, I understand better what works and what doesn’t work, and how to convey the message of the paper in a clearer way, both through the text and the figures.

 

You can find out more about Nuria and her research on her webpage and follow her on Twitter @noliva77

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Open call for papers: Themed collection on Microneedles

Biomaterials Science is delighted to announce an open call for submissions to a cross-journal themed collection on ‘Microneedles’ with companion journal Journal of Materials Chemistry B.

Guest edited by Dr Ester Caffarel-Salvador (Scientific Consultant, USA) Professor Ryan Donnelly (Queen’s University Belfast, UK), Professor Harvinder Gill (Texas Tech, USA) and Professor Hyungil Jung (Yonsei University, Korea).

 

Submissions open until 1 March 2023

 

Microneedles, since their inception as a unique transdermal drug and vaccine delivery system, have become a noteworthy system used in multiple routes, including gastrointestinal, oral (mouth cavity) and ocular, to name a few. The range of illnesses being targeted by microneedles has also increased significantly and includes infectious diseases, pain, diabetes, and allergies for example. Sensing is another upcoming application of microneedles. Innovation in microneedle fabrication continues to not only push the drug-carrying and delivering capacity of microneedles, but also making mass manufacturing feasible and economical. There is also increased activity in the commercial sector with different companies attempting to bring the first microneedle-based medical device to market.

This cross-journal themed collection on ‘Microneedles’ in Journal of Materials Chemistry B and Biomaterials Science aims to bring together recent advancements in the field of microneedles that readers will find informative and useful. The topics could include microneedle fabrication and development approaches, applications of microneedles that add a new dimension to existing core knowledge in the microneedles field, sensing applications and clinical studies that evaluate efficacy or other aspects of microneedle use in humans.

Submissions to the journal should fit within the scope of Journal of Materials Chemistry B or Biomaterials Science – Please see the journal website for more information on the journal’s scope, standards, article types and author guidelines. We encourage you to submit your work to the journal that you feel best reflects the scope of your work.

The call for papers is open for the following article types:

  • Communications
  • Full papers
  • Reviews
  • Perspectives

 

If you would like to submit to this themed collection, you can submit your article directly to the online submission platform for Journal of Materials Chemistry B or Biomaterials Science. Please mention that this submission is a contribution to the Microneedles collection in the “Themed issues” section of the submission form and add a “Note to the Editor” that this is from the Open Call. The Editorial Office reserves the right to check suitability of submissions in relation to the scope of both the journal and the collection, and inclusion of accepted articles in the final themed issue is not guaranteed.

Please note that all submissions will be subject to initial assessment by the journal editors and as such we cannot guarantee peer review or final acceptance of your manuscript. If you have any questions about the collection, email us at biomaterialsscience-rsc@rsc.org.  We look forward to receiving and featuring your submissions in this exciting collection!

 

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Biomaterials science Emerging Investigator- Kevin McHugh

Dr. Kevin McHugh is an Assistant Professor and CPRIT Scholar in Cancer Research in the Department of Bioengineering at Rice University whose work has been featured in journals such as Science, Science Translational Materials, Advanced Materials, and PNAS. Dr. McHugh received his B.S. in biomedical engineering from Case Western Reserve University in 2009 and Ph.D. in Biomedical Engineering from Boston University in 2014 where his Ph.D. work focused on developing tissue engineering scaffolds for dry age-related macular degeneration. He then joined Dr. Robert Langer’s Laboratory at the Massachusetts Institute of Technology as a Ruth L. Kirschstein Postdoctoral Fellow where he developed vaccine delivery systems with an emphasis on applications in low-resource environments. At Rice, Dr. McHugh’s lab combines customized biodegradable materials and cutting-edge fabrication techniques to create novel drug delivery systems that overcome the limitations of current vaccine and drug formulations.

Find out more about Kevin’s lab here: http://mchughlab.rice.edu/team/

You can follow Kevin on Twitter @kjmchugh1

Read Kevin’s Emerging Investigator article, ‘Multidomain Peptide Hydrogel Adjuvants Elicit Strong Bias Towards Humoral Immunity’ 

Check out our interview with Kevin below:

1. How do you feel about Biomaterials Science as a place to publish research on this topic?

Biomaterials Science consistently publishes high-quality and interesting work in the field of self-assembled drug delivery systems and immunoengineering, so it was an obvious choice for where to publish our research. The journal has been quick to adapt to the emerging area of immune modulation and reflects the great interest in both understanding and controlling the interaction between biomaterials and the immune system. In this paper, we sought to share our delivery platform as a tool to direct and modulate this interaction. We hope that our contribution to the field can be beneficial to fellow readers of Biomaterials Science just as we have benefited from the work of others who have published in the journal.

2. What aspect of your work are you most excited about at the moment and what do you find most challenging about your research?

The most exciting aspect of our work is the ability to tune the immune response by changing the sequence and chemical functionality of multidomain peptide hydrogels. These synthetic peptides are biocompatible and extremely modular, which makes them an excellent platform for immune modulation. In this recent study, we show that these materials can act as adjuvants to generate antigen-specific humoral immunity without a strong cellular immune response. In the future, we are excited to explore additional peptide modifications that can direct the adaptive immune response to preferentially evoke the cellular immune response or even a tolerogenic immune response. The most challenging aspect of our work is understanding the underlying mechanisms behind this multidomain peptide-mediated immunomodulation. Many groups working on self-assembling peptides are investigating how the body recognizes and reacts to these materials and although there has been some progress, there is still much to understand.

3. In your opinion, what are the most important questions to be asked/answered in this field of research?

One of the most important questions that we, as a field, need to answer is “what are the characteristics of peptide-based biomaterials that influence the immune response?” Once we develop a generalizable understanding of the structure-function relationships that influence the immune system, we will be able to rationally design materials that direct the immune response in an application-specific manner with high precision. Tools like alpha-fold have made great strides towards this goal, yet more work is needed to understand how the body recognizes and interacts with different peptide self-assemblies based on sequence and secondary structure.

4. Can you share one piece of career-related advice or wisdom with other early career scientists?

The most important piece of advice I can share with early-career scientists is to make sure that you pursue your research in a way that is sustainable for you. If you are working so hard that burnout is on the horizon, definitely dial it back. In the long run, it is not helpful to anyone—least of all you. The “for you” part of that advice is especially important. Try not to compare yourself to others. There are many reasons why someone else might maintain a different work schedule than you, so just focus on doing the best that you can, taking into account your personal goals, priorities, and other obligations. Also, putting in hours just for the sake of being in the lab is not helpful. Instead, plan ahead, work efficiently, and take time off when you need it.

 

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Biomaterials Science Lectureship 2023- Nominations now open

 

Do you know an early-career researcher who deserves recognition for their contribution to the biomaterials field?

Biomaterials Science is pleased to announce that nominations are now being accepted for its 2023 Lectureship award and will close on 31 December 2022. This annual award was established in 2014 to honour an early-stage career scientist who has made a significant contribution to the biomaterials field.

 

 

Eligibility

To be eligible for the lectureship, candidates should meet the following criteria:

  • Be an independent researcher, PhD students and postdoctoral research associates are not eligible
  • Be actively pursuing research within the biomaterials field, and have made a significant contribution to the field
  • Be at an early stage of their independent career (this should typically be within 12 years of attaining their doctorate or equivalent degree, but appropriate consideration will be given to those who have taken a career break, work in systems where their time period to independence may vary or who followed an alternative study path)

 

How to nominate

Nominations must be made via email to biomaterialsscience-rsc@rsc.org, and include the following:

  • The name, affiliation and contact details of the nominee, nominator and referee
  • An up-to-date CV of the nominee (1 A4 page maximum length)
  • A letter of recommendation from the nominator (500 words maximum length). The relationship between nominator and nominee should be stated in the letter.
  • A supporting letter of recommendation from a referee (500 words maximum length). This could be from the nominee’s academic mentor, PhD supervisor or postdoc for instance. The relationship between referee and nominee should be stated in the letter.
  • The nominator must confirm that to the best of their knowledge, their nominee’s professional standing is as such that there is no confirmed or potential impediment to them receiving the Lectureship

Please note:

  • Self-nomination is not permitted
  • The nominee must be aware that he/she/they have been nominated for this lectureship
  • As part of the Royal Society of Chemistry, we have a responsibility to promote inclusivity and accessibility in order to improve diversity. Where possible, we encourage each nominator to consider nominating candidates of all genders, races, and backgrounds. Please see the RSC’s approach to Inclusion and Diversity.

 

Selection

  • All eligible nominated candidates will be assessed by a judging panel made up of the Biomaterials Science Editorial Board, any Editorial Board members with a conflict of interest will be ineligible for the judging panel.
  • The judging panel will consider the following core criteria:
    • Excellence in research, as evidenced in reference to originality and impact
    • Quality of publications, patents or software
    • Innovation
    • Professional standing
    • Independence
    • Collaborations and teamwork
    • Evidence of promising potential
    • Other indicators of esteem indicated by the nominator
  • In any instance where multiple nominees are judged to be equally meritorious in relation to these core criteria, the judging panel will use information provided on the nominee’s broader contribution to the chemistry community as an additional criterion. Examples of this could include: involvement with RSC community activities, teaching or demonstrating, effective mentorship, service on boards, committees or panels, leadership in the scientific community, peer reviewing, promotion of diversity and inclusion, advocacy for chemistry, public engagement and outreach.

 

Previous winners

 

Profile picture of Yizhou Dong

Yizhou Dong, Lectureship winner 2022

 

2022- Yizhou Dong, Ohio State University, USA

2021 – Nasim Annabi, UCLA, USA

2020 – Kanyi Pu, Nanyang Technological University, Singapore

2019 – April Kloxin, University of Delaware, USA

2018 – Zhen Gu, University of North Carolina at Chapel Hill & North Carolina State University, USA

2017 – Zhuang Liu, Soochow University, China

2016 – Fan Yang, Stanford University, USA

2015 – Joel Collier, Duke University, USA

2014 – Suzie Pun, University of Washington, USA

2011 – Michael J. Solomon, University of Michigan, USA

 

Nominations deadline: 31 December 2022

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Biomaterials Science Emerging Investigator- Jianqin Lu

Jianqin Lu, BPharm, PhD, is an Assistant Professor and Director in Pharmaceutics and Pharmacokinetics Track at R. Ken Coit College of Pharmacy, The University of Arizona, Tucson, USA. Dr. Lu received his PhD in Pharmaceutics from the University of Pittsburgh and had postdoc trainings at University of Chicago and UCLA David Geffen School of Medicine/California NanoSystems Institute. Dr. Lu joined UArizona in 2019 and his lab strives to develop innovative, safe, and efficacious therapeutics at the interface of drug delivery, synthetic chemistry, pharmaceutics, nanotechnology, biomaterials, and tumor immunology to address the pressing unmet needs in cancer and other diseases therapy and prevention.

Dr. Lu’s research work has been published in Nature Nanotechnology, Nature Communications, Biomaterials, etc, and has resulted in a Maximizing Investigators’ Research Award (MIRA) (R35) from NIH/NIGMS, a Pharmaceutical Research and Manufacturers of America (PhRMA) Foundation Research Starter Grant in Drug Delivery, and several pilot and seed grants from the State of Arizona’s Technology and Research Initiative Fund (TRIF)/BIO5 Institute and NIH-sponsored The Southwest Environmental Health Sciences Center.

Recipient of the Norman R. and Priscilla A. Farnsworth Award at the University of Pittsburgh, the NIH/NCI Ruth L. Kirschstein Institutional National Research Service Award (T32) in Tumor Immunology at UCLA, and the 2022 American Association of Colleges of Pharmacy (AACP) Pharmaceutics Research Award, Dr. Lu was the Secretary of Knowledge Management in AACP Pharmaceutics Section and serves as the Associate Editor for Frontiers in Medical Technology: Nano-Based Drug Delivery.You can follow Jianqin Lu on Twitter @JianqinLu_Lab or on LinkedIn

Read Jianqin’s Emerging Investigator article, ‘Surface-Modified Nanotherapeutics Targeting Atherosclerosis Efficiency’ 

Check out our interview with Jianqin below:

1. How do you feel about Biomaterials Science as a place to publish research on this topic?

Biomaterials Science is one of the leading journals in the field for biomaterials, drug delivery, and nanomedicine. I found Biomaterials Science is the perfect place to publish this piece of work, which enables widespread visibility to a large amount of audience.

 

2. What aspect of your work are you most excited about at the moment and what do you find most challenging about your research?

To create innovative, safe and efficacious nanotherapeutic platform for the improved drug and gene delivery for treating various diseases including cancers and atherosclerosis. To find clinically relevant animal models for testing the developed nanomedicines, which enables good correlation with human patients.

 

3. In your opinion, what are the most important questions to be asked/answered in this field of research?

How can the improved nanocarriers be used to further enhance the therapeutic delivery of various drugs.

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Biomaterials Science Emerging Investigator- Catherine Fromen

 

Catherine Fromen is an Assistant Professor in the Department of Chemical and Biomolecular Engineering at the University of Delaware. She received her PhD in Chemical Engineering from North Carolina State University in 2014 and performed postdoctoral studies at the University of Michigan as a University of Michigan’s President’s Postdoctoral Fellow. She joined the University of Delaware in 2017, where her research group focuses on applying chemical engineering principles to challenges surrounding pulmonary drug delivery. Her research and publications have spanned the design of inhalable immune-modulatory formulations and the development of experimental dynamic, full volume approximations of the airways. Prof. Fromen has authored over 40 manuscripts and patents and her team’s work has been recognized with recent awards, including receiving the AIChE’s 35 Under 35 Award, Univ Delaware Excellence in Mentoring Award, AIChE Delaware Valley Section Outstanding Faculty Award, PhRMA Foundation Research Starter Grant, and an NIH ESI MIRA Award. She is an active member of numerous professional societies, including ISAM (International Society of Aerosols in Medicine), ATS (American Thoracic Society), AAPS INC (American Association of Pharmaceutical Scientists Inhalation and Nasal Community), AIChE (American Institute for Chemical Engineers), and SFB (Society of Biomaterials), among others.

Read Catherine’s Emerging Investigator article, ‘Destructive fibrotic teamwork: how both microenvironment stiffness and profibrotic interleukin 13 impair alveolar macrophage phenotype and function’

Check out Catherine’s lab group webpage to find out more about the group’s research https://sites.udel.edu/cfromen/

You can follow Catherine on Twitter @cfromen and @FromenLab or on LinkedIn https://www.linkedin.com/in/cathy-fromen/

 

Read our interview below:

1. How do you feel about Biomaterials Science as a place to publish research on this topic?

I was incredibly excited to receive an invitation to be featured in the Emerging Investigator Series of Biomaterials Science because this journal is one of the top places I look for exciting research within biomaterials and models of the lung, more specifically. Our manuscript introduces a biomaterials-based model of the human airway to evaluate changes to innate immune cells within a fibrotic-like microenvironment. Fibrosis remains such a complex and challenging set of diseases to treat and biomaterial-based models have a tremendous opportunity to unravel this complexity and provide opportunities to screen new therapeutic approaches. Biomaterials Science has been a leader in publishing many influential papers discussing biomaterials approaches to modelling, understanding, and treating fibrosis and I am very proud to contribute our piece in advancing this important field.

2. What aspect of your work are you most excited about at the moment and what do you find most challenging about your research?

I am certainly excited by the advances that biomaterials have enabled in engineering complex microenvironments that can mimic pulmonary tissue: in structure, composition, and barrier properties. I am even more excited about how these emerging models can be used to predict therapeutic responses in the lung. For inhaled medicines especially, it remains exceedingly difficult to directly sample responses in the airway to understand how inhaled formulations act in the lung; new, complex models will be critical in improving predictive capabilities and advancing inhaled therapeutics, such as inhaled vaccines or immunotherapies. It’s challenging to think about how far we have to go, but motivating at the same time.

3. In your opinion, what are the most important questions to be asked/answered in this field of research?

This a tough question; how to pick just one! For inhaled drug delivery, the big questions are “how can we predict where an inhaled agent goes?” and once there, “how does it work?”, especially in directing local immune responses. Answering these questions will allow us to develop more complex inhalable immunotherapies and better treat patients with respiratory conditions.

4. Can you share one piece of career-related advice or wisdom with other early career scientists?

Find your “people” – in life, in your institution, in your professional societies, in your students – and work to maintain those connections. They’re the ones who will pick you up when you fall, cheer for you when you need it most, and open doors you didn’t even know existed.

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