Archive for November, 2012

Biomaterials Science Issue 1 now online!

Less than a year after the launch announcement, the first issue of Biomaterials Science is now available online. Showcasing the latest biomaterials research, Issue 1 contains articles on the following:

Enzyme responsive materials, Rein V. Ulijn et al.: This review summarises recent advances in enzyme responsive material development, highlighting design strategies and future challenges in the field.

Bone repair using bioceramics, María Vallet-Regí et al.: Understanding natural ossification mechanisms is essential for designing scaffolds for bone tissue engineering. Mesoporous bioactive ceramics formed scaffolds by rapid prototyping and are excellent candidates for bone regeneration.

Zn and Sr substitution in tricalcium phosphate on osteoclast differentiation and resorption, Susmita Bose et al.: Tunable osteoclast cell differentiation and resorption of β-TCP bone substitute was achieved by Zn and/or Sr doping—a much needed property for successful bone remodelling.

A bio-inspired neural environment to control neurons, Morgan R. Alexander et al.: Chemical and micro-topographical gradients are used as a high-throughput means to assess neural cell interaction. Surface conditioning by radial glial cells enhances neuron attachment and alignment.


All articles published in Biomaterials Science are free to access online to all individuals who sign up for an RSC Publishing personal account, and all the existing RSC customers with an IP address registered.

Like what you read? Submit your work to Biomaterials Science now. Your articles will benefit from wide exposure with free access upon registration to all content published during 2013 and 2014 giving maximum visibility to your work.

Follow the latest journal news on Twitter @BioMaterSci or go to our Facebook page.

To keep up-to-date with all the latest research, sign-up to our RSS feed or Table of contents alert.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Hot paper: Bio-ink for printing living cells on demand

A bio-ink to print living cells onto a surface using a commercial printer has been developed by Dr Marc in het Panhuis and colleagues at the University of Wollongong, Australia. Bioprinting can be used for tissue engineering and analytical applications. The bio-ink consists of a gel – gellan gum – that’s used in food additives. The gel makes sure that the cells in the bio-ink remain suspended with no sign of aggregation, which was the problem with previous inks. Aggregation means an uneven distribution of cells being printed out onto a surface.

Bio-ink for printing living cells on demand

Biomater. Sci., 2012, Advance Article.  DOI: 10.1039/c2bm00114d

Follow the latest journal news on Twitter @BioMaterSci or go to our Facebook page.

To keep up-to-date with all the latest research, sign-up to our RSS feed or Table of contents alert.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Nasal gel alternative to insulin injection: Biomaterials Science article in Chemistry World

The formulation affects the controlled delivery of insulin, demonstrated by a reduction in blood glucose over 24 hours. © Shutterstock

An international team of scientists has developed a novel insulin delivery system for nasal administration. The study aims to provide an alternative to regular injections through the delivery of insulin via the nasal membrane in the form of a hydrogel. This route offers a relatively high bioavailability, avoidance of the first-pass effect (in which a drug’s concentration is reduced before it reaches the systemic circulation) and painless administration.

Considerable research effort has been dedicated to developing alternative non-invasive insulin delivery systems, including oral and transcutaneous administration. The major limitations of nasal delivery are the rapid mucociliary clearance of a drug to the nasopharynx, resulting in a short time span for its absorption, and the low permeability of the nasal membrane to peptides such as insulin because of tight junctions between epithelial cells.

Read the full article by Michael Parkin in Chemistry World.

A once-a-day dosage form for the delivery of insulin through the nasal route: in vitro assessment and in vivo evaluation
H. Nazar ,  P. Caliceti ,  B. Carpenter ,  A. I. El-Mallah ,  D. G. Fatouros ,  M. Roldo ,  S. M. van der Merwe and J. Tsibouklis
Biomater. Sci., 2013, Advance Article
DOI: 10.1039/C2BM00132B

Follow the latest journal news on Twitter @BioMaterSci or go to our Facebook page.

To keep up-to-date with all the latest research, sign-up to our RSS feed or Table of contents alert.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Ink containing living cells to print tissue: Biomaterials Science article in Chemistry World

Printing cellsScientists in Australia are a step closer to printing living cells for tissue engineering with the development of a new bio-ink that allows the cells to stay alive until they are printed and not clog up the printer nozzle.

‘The first bio-inks used in drop-on-demand cell printing were simple salt solutions,’ says Marc in het Panhuis, who was part of the research team at the University of Wollongong. ‘The cells in these inks settled and aggregated quickly, which impeded printing. Cell viability can also be compromised if the salt concentration is too high.’

Read the full article in Chemistry World.


 

Bio-ink for on-demand printing of living cells
Cameron J. Ferris,  Kerry J. Gilmore,  Stephen Beirne,  Donald McCallum,  Gordon G. Wallace and Marc in het Panhuis
Biomater. Sci., 2013, Advance Article
DOI: 10.1039/C2BM00114D

Follow the latest journal news on Twitter @BioMaterSci or go to our Facebook page.

To keep up-to-date with all the latest research, sign-up to our RSS feed or Table of contents alert.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

Fabrication of scaffolds for regenerative medicine from electrospinning and additive manufacturing minireview

Producing scaffolds for use in tissue engineering is a major focus in the field. Electrospinning and additive manufacturing are two of the methods in which scaffolds can be fabricated. Additive manufacturing is broadly defined as the construction of complex structures in a layer-by-layer fashion using computer aided design.

This minireview by Dalton, Hutmacher and colleagues from the Institute for Health and Biomedical Innovation at Queensland University of Technology describes solution and melt electrospinning use in conjunction with additive manufacturing for tissue engineering scaffolds. The minireview describes the emerging areas of biomodal and multiphasic scaffolds, and scaffolds published using melt electrospinning writing as an additive manufacturing technique.

Electrospinning and additive manufacturing: converging technologies
Biomater. Sci., 2012, Advance Article.  DOI: 10.1039/c2bm00039c

Follow the latest journal news on Twitter @BioMaterSci or go to our Facebook page.

To keep up-to-date with all the latest research, sign-up to our RSS feed or Table of contents alert.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)