Archive for the ‘Hot Article’ Category

HOT Article: Detecting mercury(II) ions

Amplified fluorescence detection of mercury(II) ions (Hg2+) using target-induced DNAzyme cascade with catalytic and molecular beaconsA new biosensor that uses a target-induced DNAzyme cascade with catalytic and molecular beacons (CAMB) to fluorescently detect mercury(II) ions in water has been designed by a team from China. Yongxi Zhao from Xi’an Jiaotong University and colleagues tested the biosensor on river water samples with satisfactory results. Click on the title below to read more.

Amplified fluorescence detection of mercury(II) ions (Hg2+) using target-induced DNAzyme cascade with catalytic and molecular beacons
Lin Qi, Yongxi Zhao, Hui Yuan, Kai Bai, Yue Zhao, Feng Chen, Yanhua Dong and Yayan Wu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35437C

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HOT articles from Analyst this April

It’s been a busy month with so many great papers, so here are some HOT articles from Analyst that you might have missed this April!

Why not take a look, they will be free to read for 2 weeks.

Analysis of immunoarrays using a gold grating-based dual mode surface plasmon-coupled emission (SPCE) sensor chip
Jong Seol Yuk, George N. Gibson, James M. Rice, Ernest F. Guignon and Michael A. Lynes
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35143A

Selective recognition of xylene isomers using ZnO–SWNTs hybrid gas sensors
S. C. Hernández, C. M. Hangarter, A. Mulchandani and N. V. Myung
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35168D

Time-dependent nanogel aggregation for naked-eye assays of α-amylase activity
Hui Jiang and Xuemei Wang
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN00038E

Fast and sensitive dye-sensor based on fluorescein/reduced graphene oxide complex
Sheng Tian Huang ,  Yan Shi ,  Nian Bing Li and Hong Qun Luo
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35099H

New poly(ionic liquid)-grafted silica multi-mode stationary phase for anion-exchange/reversed-phase/hydrophilic interaction liquid chromatography
Hongdeng Qiu, Abul K. Mallik, Makoto Takafuji, Shengxiang Jiang and Hirotaka Ihara
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35348B

An electrochemical thermometer: voltammetric measurement of temperature and its application to amperometric gas sensing
Linhongjia Xiong, Ai M. Fletcher, Sven Ernst, Stephen G. Davies and Richard G. Compton
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35336A

A fluorous synthetic receptor that recognizes perfluorooctanoic acid (PFOA) via fluorous interaction obtained by molecular imprinting
Megumi Takayose,  Kenji Nishimoto and Jun Matsui
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN15936H

Detection of DNA based on fluorescence resonance energy transfer of polyelectrolyte-protected CdTe quantum dots as energy donors
Ting Qiu, Bin Zhang, Zi-yang Hu, Jian-hua Tang, Hong-ping Xie and Bing-ren Gu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35229J

DNA-templated silver nanoclusters–graphene oxide nanohybrid materials: a platform for label-free and sensitive fluorescence turn-on detection of multiple nucleic acid targets
Yu Tao, Youhui Lin, Zhenzhen Huang, Jinsong Ren and Xiaogang Qu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35373C

A hyphenated optical trap capillary electrophoresis laser induced native fluorescence system for single-cell chemical analysis
Christine Cecala, Stanislav S. Rubakhin, Jennifer W. Mitchell, Martha U. Gillette and Jonathan V. Sweedler
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35198F

Production of novel polymer monolithic columns, with stationary phase gradients, using cyclic olefin co-polymer (COC) optical filters
Sinéad Currivan,  Damian Connolly and Brett Paull
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35316D

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HOT articles in Issue 10

Rapid analysis of whole blood by paper spray MS: Epsy et al., Analyst, 2012,137, 2344-2349

Once you’ve enjoyed the great covers, have a look at the collection of HOT articles in the latest issue of Analyst.

There’s a review from Richard Compton on electrochemical determination of glutathione, papers from Editorial Board members Duncan Graham and Graham Cooks as well as many other on an array of topics (no pun intended!).

(more…)

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HOT Article: Fast measurement of binding kinetics

Fast measurement of binding kinetics with dual slope SPR microchips

Ghosh & Mastrangelo, Analyst, 2012, Advance Article

Tridib Ghosh and Carlos H. Mastrangelo from the University of Utah, USA, have developed a new dual slope SPR technique that is 10-fold faster than conventional methods. They have based the technique on the measurement of association and dissociation slopes in two half reactions. Results could be measured in 30 sec compared to 5 mins.

This HOT paper will be free to access for 2 weeks. So click through here to read more!

Fast measurement of binding kinetics with dual slope SPR microchips
Tridib Ghosh and Carlos H. Mastrangelo
Analyst, 2012, 137, 2381-2385
DOI: 10.1039/C2AN35045A

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HOT article: “Turn on” electron-transfer-based selective detection of ascorbic acid

“Turn-on” optical detection of parts-per-million (ppm) levels of ascorbic acid in water using a redox-active monolayer on glass

Singh et al., Analyst, 2012, Advance Article

The design and fabrication of monolayer-based sensors for various chemicals, gases, metal ions, explosives and biologically relevant molecules have received much attention recently. In particular, optical sensors are of great interest due to the advantage that the sensing system does not need to be directly wired with large scale electronics.

In this paper, Tarkeshwar Gupta of the University of Delhi, Delhi, India, and colleagues describe the “turn-on” optical detection of parts-per-million (ppm) levels of ascorbic acid in water using a redox-active monolayer on glass.

Their system is based on a nondestructive solution-to-surface one-electron transfer process that can be read out optically with an off-the-shelf UV/vis spectrophotometer.

Communication: “Turn on” electron-transfer-based selective detection of ascorbic acid via copper complexes immobilized on glass
Vikram Singh, Prakash Chandra Mondal, Jeyachandran Yekkoni Lakshmanan, Michael Zharnikov and Tarkeshwar Gupta
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN16197D

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HOT Articles from Analyst

Check out some of the HOT articles that have been published with Analyst this month!

A solution-based nano-plasmonic sensing technique by using gold nanorods

Ho & Imae et al., Analyst, 2012, Advance Article

Fu Han Ho, Toyoko Imae and co-workers from the National Taiwan University of Science and Technology have successfully developed a unique sensing technique for monitoring the variation of solution concentrations and measuring the effective dielectric constant in a medium by using an ultra-small and label-free nanosensor.

A solution-based nano-plasmonic sensing technique by using gold nanorods
Fu Han Ho, Yung-Han Wu, Masaki Ujihara and Toyoko Imae
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35101C

Upconversion emission of fluorescent silver nanoclusters and in situ selective DNA biosensing

Shao et al., Analyst, 2012, Advance Article

Yong Shao and colleagues from Zhejiang Normal University have studied the upconversion emission of Ag nanoclusters templated by single- and double-stranded DNAs in their investigation of sensor design.

Upconversion emission of fluorescent silver nanoclusters and in situ selective DNA biosensing
Qinghua Cui, Yong Shao, Kun Ma, Shujuan Xu, Fei Wu and Guiying Liu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN00025C

Jin Ouyang from Beijing Normal University and fellow Chinese scientists have made a simple small-molecule fluorescent probe, designed for the detection of human serum proteins via hydrophobic interactions after polyacrylamide gel electrophoresis. The new probe proved to be a good protein reporter due to its fast staining procedure. It also had low detection limits and high resolution.

The development of simple and sensitive small-molecule fluorescent probes for the detection of serum proteins after native polyacrylamide gel electrophoresis

Ouyang et al., Analyst, 2012, Advance Article

The development of simple and sensitive small-molecule fluorescent probes for the detection of serum proteins after native polyacrylamide gel electrophoresis
Fangfang Wang, Lingyun Huang, Na Na, Dacheng He, Dezhi Sun and Jin Ouyang
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35265F

A team from Canada have tackled the issue of the detection of contamination of jet fuels with aero-turbine lubricating oil in a paper from Hans-Peter Loock, from Queen’s University.

Fluorescence excitation–emission matrix (EEM) spectroscopy and cavity ring-down (CRD) absorption spectroscopy of oil-contaminated jet fuel using fiber-optic probes

Loock et al., Analyst, 2012, Advance Article

Fluorescence excitation–emission matrix (EEM) spectroscopy and cavity ring-down (CRD) absorption spectroscopy of oil-contaminated jet fuel using fiber-optic probes
Hengameh Omrani, Jack A. Barnes, Alexander E. Dudelzak, Hans-Peter Loock and Helen Waechter
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35091B

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HOT Article: Point-of-care blood analysis

This month we have a HOT article from our Analyst Editorial Board member, Graham Cooks. Working with his colleagues from Purdue University, USA, they have developed a rapid, point-of-care method to test whole blood samples that have been supported on filter paper using paper spray mass spectrometry. Addition of a coagulant called alum allowed the sample to be tested right away. The technique was tested on the analysis of therapeutic drugs in blood samples. Click through here to read more. The paper will be free to access for 2 weeks!

Rapid analysis of whole blood by paper spray mass spectrometry for point-of-care therapeutic drug monitoring

Cooks et al., Analyst, 2012, Advance Article

Rapid analysis of whole blood by paper spray mass spectrometry for point-of-care therapeutic drug monitoring
Ryan D. Espy, Nicholas E. Manicke, Zheng Ouyang and R. Graham Cooks
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35082C

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HOT articles from Issue 9

Electroanalysis for metal-based impurities in graphenes

Chee & Pumera, Analyst, 2012, 137, 2039-2041

It’s hot hot hot in the latest issue of Analyst, with 14 HOT articles featuring the best in analytical science.  Including: a review on the detection of α-amino-β-methylaminopropionic acid, mid-IR spectroscopy for salivary calculi, fluorescent chemosensing of Ag+, and an artificial nose.

(more…)

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HOT Article: Electrochemical determination of glutathione

Electrochemical determination of glutathione: a review

Compton et al., Analyst, 2012, Advance Article

In this HOT review paper, Richard Compton and co-workers from Oxford University discuss the importance of glutathione determination, which has been shown to have physiological importance in diseases such as Parkinson’s, diabetes and cancer. Because of its medical significance, it is important to have quick and easy assays to aid clinical diagnostics and treatment. Click here to read more!

Electrochemical determination of glutathione: a review
John C. Harfield, Christopher Batchelor-McAuley and Richard G. Compton
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35090D

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HOT Article: Solvation-based screening for metabolite arrays

A solvation-based screening approach for metabolite arrays

Vaidyanathan et al., Analyst, 2012, Advance Article

In this HOT paper Seetharaman Vaidyanathan and colleagues from the University of Sheffield explore a new method for screening metabolites based on an array format, using relative polarity and selective solvent dissolution. This approach has the potential to be a successful way of rapidly screening metabolomes and it will allow the simultaneous screening and profiling of multiple samples.

A solvation-based screening approach for metabolite arrays
Malinda Salim, Phillip C. Wright and Seetharaman Vaidyanathan
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN16318G

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