Ghosh & Mastrangelo, Analyst, 2012, Advance Article
Tridib Ghosh and Carlos H. Mastrangelo from the University of Utah, USA, have developed a new dual slope SPR technique that is 10-fold faster than conventional methods. They have based the technique on the measurement of association and dissociation slopes in two half reactions. Results could be measured in 30 sec compared to 5 mins.
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Fast measurement of binding kinetics with dual slope SPR microchips
Tridib Ghosh and Carlos H. Mastrangelo
Analyst, 2012, 137, 2381-2385
DOI: 10.1039/C2AN35045A
