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Is food allergen analysis flawed?

Dairy products

© Shutterstock

It’s Allergy Awareness Week 25 April – 1 May, 2016.

There are around 21 million people who suffer from allergies in the UK alone.  Allergy UK is the leading national charity dedicated to supporting these people, and provides a dedicated helpline and online forums. Allergy Awareness Week hopes to draw attention to a number of allergies and promote well-being in those individuals who suffer from them.

Researchers at LGC, The Queen’s University of Belfast, Allergy Action, and the University of Manchester have combined to produce a critical review published in Analyst on the flaws in the analysis of food allergens that could jeopardise their future risk management, as well as ways to address those flaws. Follow the link below to read their review.


© Shutterstock

Is food allergen analysis flawed? Health and supply chain risks and a proposed framework to address urgent analytical needs
M. J. Walker, D. T. Burns, C. T. Elliott, M. H. Gowland and E. N. Clare Mills
Analyst, 2016, 141, 24-35
DOI: 10.1039/C5AN01457C

Check out the Chemistry World comment on allergies from Michael Walker here.

Interested to read more about food testing? Try the ‘Detecting food authenticity and integrity‘ online collection: A compilation of papers showcasing the latest discoveries and developments in the analysis and detection of food fraud, contamination, adulteration and spoilage.

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DOI: 10.1039/C4AN01743A

Ion Creation, Ion Focusing, Ion/Molecule Reactions, Ion Separation, and Ion Detection in the Open Air in a Small Plastic Device
Zane Baird, Pu Wei and R. Graham Cooks
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01929F

Comparison of FTIR transmission and transflection substrates for canine liver cancer detection
Kamila Kochan, Philip Heraud, Matti Kiupel, Vilma Yuzbasiyan-Gurkan, Don McNaughton, Malgorzata Baranska and Bayden R. Wood
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01901F

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HOT articles in Analyst

Take a look at our most recent HOT Analyst articles, these are now free to access for the next few weeks!

Propofol Detection and Quantification in Human Blood: The Promise of Feedback Controlled, Closed-loop Anesthesia
Francine Kivlehan, Edward Chaum and Erno Lindner
Analyst, 2015, Advance Article
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Graphical Abstract
Direct Analysis of in-Gel Proteins by Carbon Nanotubes-Modified Paper Spray Ambient Mass Spectrometry
Feifei Han, Yuhan Yang, Jin Ouyang and Na Na
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01688B

Responsive Ionic Liquid-Polymer 2D Photonic Crystal Gas Sensors

Natasha L. Smith, Zhenmin Hong and Sanford A. Asher
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Label-Free Fluorescence Detection of DNA Methylation and Methyltransferase Activity Based on Restriction Endonuclease HpaII and Exonuclease III
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Analyst, 2014, 139, 6387-6392
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Autocatalytic Amplified Detection of DNA Based on CdSe Quantum Dots/Folic Acid Electrochemiluminescence Energy Transfer System

Guifen Jie, Yingqiang Qin, Qingmin Meng and Jialin Wang
Analyst, 2015, Advance Article
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Carbon nanotube/gold nanoparticle composite–coated membrane as a facile plasmon–enhanced interface for sensitive SERS sensing
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Analyst, 2015, Advance Article
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Graphical Abstract
UV Photodissociation of trapped ions following ion mobility separation in a Q-ToF mass spectrometer
Bruno Bellina, Jeffery. M. Brown, Jakub Ujma, Paul Murray, Kevin Giles, Michael Morris, Isabelle Compagnon and Perdita. E. Barran
Analyst, 2014, 139, 6348-6351
DOI: 10.1039/C4AN01656D

Oligopeptide-heavy metal interaction monitoring by hybrid gold nanoparticles based assay
Jane Politi, Jolanda Spadavecchia, Mario Iodice and Luca de Stefano
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01491J

Hydrazinonicotinic acid as a novel matrix for highly sensitive and selective MALDI-MS analysis of oligosaccharides
Jing Jiao, Ying Zhang, Pengyuan Yang and Haojie Lu
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DOI: 10.1039/C4AN01659A

Development of Transmission Raman Spectroscopy towards the In Line, High Throughput and Non-Destructive Quantitative Analysis of Pharmaceutical Solid Oral Dose
Julia A. Griffen, Andrew W. Owen and Pavel Matousek
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01798F

An adaptable stage perfusion incubator for the controlled cultivation of C2C12 myoblast cells

Felix Kurth, Alfredo Franco-Obregón, Christoph A. Bärtschi and Petra. S. Dittrich
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01758G

Surface Charge, Electroosmotic Flow and DNA Extension in Chemically Modified Thermoplastic Nanoslits and Nanochannels

Franklin I. Uba, Swathi R. Pullagurla, Nichanun Sirasunthorn, Jiahao Wu, Sunggook Park, Rattikan Chantiwas, Yoon-Kyoung Cho, Heungjoo Shin and Steven A. Soper
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01439A

Graphical Abstract
A Pressure-Driven Capillary Electrophoretic System with Injection Valve Sampling
Chao Han, Jiannan Sun, Jinhua Liu, Heyong Cheng and Yuanchao Wang
Analyst, 2015, Advance Article
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Fluorescence polarization immunoassays for monitoring nucleoside triphosphate diphosphohydrolase (NTPDase) activity
Amelie Fiene, Younis Baqi, Joanna Lecka, Jean Sévigny and Christa E. Müller
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01694G

The “V-junction”: a novel structure for high-speed generation of bespoke droplet flows
Yun Ding, Xavier Casadevall i Solvas and Andrew deMello
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01730G

Make PyrophosphateVisible: The First Precipitable and Real-time Fluorescent Sensor for Pyrophosphate in Aqueous Solution
Shu-Yan Jiao, Kun Li, Xin Wang, Zeng Huang, Lin Pu and Xiao-Qi Yu
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01615G

Constructing a FRET-based molecular chemodosimeter for cysteine over homocysteine and glutathione by naphthalimide and phenazine derivatives
Lin Yang, Weisong Qu, Xiao Zhang, Yandi Hang and Jianli Hua
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01732C

High pH sensing with water-soluble porpholactone derivatives and their incorporation into a Nafion® optode membrane
Jill L. Worlinsky, Steven Halepas, Masoud Ghandehari, Gamal Khalil and Christian Brückner
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01462F

Graphical Abstract
Photothermal deflectometry enhanced by total internal reflection enables non-invasive glucose monitoring in human epidermis

M. A. Pleitez, O. Hertzberg, A. Bauer, M. Seeger, T. Lieblein, H. v. Lilienfeld-Toal and W. Mäntele
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN01185F

Exploring Copper Nanostructures as highly uniform and reproducible substrates for Plasmon-enhanced Fluorescence
D. Volpati, E. R. Spada, C. C. Plá Cid, M. L. Sartorelli, R. F. Aroca and C. J. L. Constantino
Analyst, 2015, Advance Article
DOI: 10.1039/C4AN00889H

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A Smart Ink for the Assessment of Low Activity Photocatalytic Surfaces
Andrew Mills, Christopher O’Rourke and Nathan Wells
Analyst, 2014, 139, 5409-5414
DOI: 10.1039/C4AN01375A

Graphical Abstract

Screen-Printed Back-to-Back Electroanalytical Sensors
Jonathan P. Metters, Edward P. Randviir and Craig E. Banks
Analyst, 2014, 139, 5339-5349
DOI: 10.1039/C4AN01501K

Fabrication and laser patterning of polystyrene optical oxygen sensor films for lab-on-a-chip applications
S. M. Grist, N. Oyunerdene, J. Flueckiger, J. Kim, P. C. Wong, L. Chrostowski and K. C. Cheung
Analyst, 2014, 139, 5718-5727
DOI: 10.1039/C4AN00765D

Reactive intermediate detection in real time via paper assisted thermal ionization mass spectrometry
Jiying Pei, Yanbiao Kang and Guangming Huang
Analyst, 2014, 139, 5354-5357
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DNA Bioassay-on-Chip using SERS Detection for Dengue Diagnosis
Hoan T. Ngo, Hsin-Neng Wang, Andrew M. Fales, Bradly P. Nicholson, Christopher W. Woods and Tuan Vo-Dinh
Analyst, 2014, 139, 5655-5659
DOI: 10.1039/C4AN01077A

Aptasensor for potassium based on RecJf exonuclease mediated signal amplification
Peng Miao, Yuguo Tang, Bidou Wang, Kun Han, Xifeng Chen and Haixuan Sun
Analyst, 2014, 139, 5695-5699
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Rapid, Highly Sensitive Detection of Herpes Simplex Virus-1 using Multiple Antigenic Peptide-Coated Superparamagnetic Beads
Ying-Fen Ran, Conor Fields, Julien Muzard, Viktoryia Liauchuk, Michael Carr, William Hall and Gil U. Lee
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00774C

New algorithm for identification of components in a mixture: application to Raman spectra of solid amino acids

Sylwester Gawinkowski, Agnieszka Kaminska, Tomasz Rolinski and Jacek Waluk
Analyst, 2014, 139, 5755-5764
DOI: 10.1039/C4AN01159G

Cold neutron diffraction contrast tomography of polycrystalline material
S. Peetermans, A. King, W. Ludwig, P. Reischig and E. H. Lehmann
Analyst, 2014, 139, 5765-5771
DOI: 10.1039/C4AN01490A

Tailoring recognition clefts from non-specific recognition matrices in mixed molecular arrays
Nivarthi Ramesh and Archita Patnaik
Analyst, 2014, 139, 5772-5780
DOI: 10.1039/C4AN01120A

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Glyconanoparticles for colorimetric bioassays
María J. Marín, Claire L. Schofield, Robert A. Field and David A. Russell
Analyst, 2015, Advance Article
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Nanocoax for Optical and Electronic Devices
Binod Rizal, Juan M. Merlo, Michael J. Burns, Thomas C. Chiles and Michael J. Naughton
Analyst, 2015, Advance Article
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3D printed metal columns for capillary liquid chromatography
S. Sandron, B. Heery, V. Gupta, D. A. Collins, E. P. Nesterenko, P. N. Nesterenko, M. Talebi, S. Beirne, F. Thompson, G. G. Wallace, D. Brabazon, F. Regan and B. Paull
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN01476F

Droplet microfluidics in (bio) chemical analysis
Evgenia Yu Basova and Frantisek Foret
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN01209G

A TEM protocol for quality assurance of in vitro cellular barrier models and its application to the assessment of nanoparticle transport mechanisms across barriers
Dong Ye, Kenneth A. Dawson and Iseult Lynch
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN01276C

A novel molecularly imprinted chitosan-acrylamide, graphene, ferrocene composite cryogel biosensor used to detect microalbumin
Amin Fatoni, Apon Numnuam, Proespichaya Kanatharana, Warakorn Limbut and Panote Thavarungkul
Analyst, 2014, Advance Article
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Rapid identification of synthetic colorants in food samples by using indium oxide nanoparticle-functionalized porous polymer monolith coupled with HPLC-MS/MS
Ruifang Qi, Xiao Zhou, Xiqian Li, Jiutong Ma, Chunmei Lu, Jun Mu, Xuguang Zhang and Qiong Jia
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN01392A

Graphical Abstract

HPLC-MRM Relative Quantification Analysis of Fatty Acids Based on a Novel Derivatization Strategy
Tie Cai,Hu Ting, Zhang Xin-Xiang, Zhou Jiangb and Zhang Jin-Lan
Analyst, 2014, 139, 6154-6159
DOI: 10.1039/C4AN01314J

Multimodal Optical Characterisation of Collagen Photodegradation by Femtosecond Infrared Laser Ablation

A. Manickavasagam, L. M. Hirvonen, L. N. Melita, E. Z. Chong, R. J. Cook, L. Bozecc and F. Festy
Analyst, 2014, 139, 6135-6143
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Ion Collision Cross Section Measurements in Quadrupole Ion Traps Using a Time-frequency Analysis Method
Muyi He, Dan Guo, Yu Chen, Xingchuang Xiong, Xiang Fangc and Wei Xu
Analyst, 2014, 139, 6144-6153
DOI: 10.1039/C4AN01216J

Label-Free Detection of DNA by Combining Gated Mesoporous Silica and Catalytic Signal Amplification of Platinum Nanoparticle
Zhifei Wang, Xia Yang, Jie Feng, Yongjun Tang, Yanyun Jianga and Nongyue He
Analyst, 2014, 139, 6088-6091
DOI: 10.1039/C4AN01539H

Molecular phenotypic profiling of a Saccharomyces cerevisiae strain at the single-cell level
A. Mareike Schmidt, Stephan R. Fagerer, Konstantins Jefimovs, Florian Buettner, Christian Marro,   Erdem C. Siringil, Karl L. Boehlen, Martin Pabstb and Alfredo J. Ibáñez
Analyst, 2014, 139, 5709-5717
DOI: 10.1039/C4AN01119H

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Take a look at our recent HOT Analyst articles, these are now free to access for the next few weeks!

A label-free activatable aptamer probe for colorimetric detection of cancer cells based on binding-triggered in situ catalysis of split DNAzyme
Hui Shi, Duo Li, Fengzhou Xu, Xiaoxiao He, Kemin Wang, Xiaosheng Ye, Jinlu Tang and Chunmei He  
Analyst, 2014,139, 4181-4184
DOI: 10.1039/C4AN00561A, Communication

A three-dimensional interpenetrating electrode of reduced graphene oxide for selective detection of dopamine
Xiaowen Yu, Kaixuan Sheng and Gaoquan Shi  
Analyst, 2014,139, 4525-4531
DOI: 10.1039/C4AN00604F, Paper

Fine structural features of nanoscale zero-valent iron characterized by spherical aberration corrected scanning transmission electron microscopy (Cs-STEM)
Airong Liu and Wei-xian Zhang  
Analyst, 2014,139, 4512-4518
DOI: 10.1039/C4AN00679H, Paper

On-chip monitoring of skeletal myoblast transplantation for the treatment of hypoxia-induced myocardial injury
Juan He, Chao Ma, Wenming Liu and Jinyi Wang  
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Global in vivo terminal amino acid labeling for exploring differential expressed proteins induced by dialyzed serum cultivation
Li-Qi Xie, Ai-Ying Nie, Shu-Jun Yang, Chao Zhao, Lei Zhang, Peng-Yuan Yang and Hao-Jie Lu  
Analyst, 2014,139, 4497-4504
DOI: 10.1039/C4AN00728J, Paper

A novel variable selection approach that iteratively optimizes variable space using weighted binary matrix sampling
Bai-chuan Deng, Yong-huan Yun, Yi-zeng Liang and Lun-zhao Yi  
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00730A, Paper

Using electron paramagnetic resonance to map N@C60 during high throughput processing
Simon R. Plant and Kyriakos Porfyrakis  
Analyst, 2014,139, 4519-4524
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Affinity-based precipitation via a bivalent peptidic hapten for the purification of monoclonal antibodies
Michael W. Handlogten, Jared F. Stefanick, Peter E. Deak and Basar Bilgicer  
Analyst, 2014,139, 4247-4255
DOI: 10.1039/C4AN00780H, Paper

Real-time detection of metal ions using conjugated polymer composite papers
Ji Eun Lee, Hyeon Woo Shim, Oh Seok Kwon, Yang-Il Huh and Hyeonseok Yoon  
Analyst, 2014,139, 4466-4475
DOI: 10.1039/C4AN00804A, Paper

Identification and discrimination of binding sites of an organoruthenium anticancer complex to single-stranded oligonucleotides by mass spectrometry
Suyan Liu, Kui Wu, Wei Zheng, Yao Zhao, Qun Luo, Shaoxiang Xiong and Fuyi Wang  
Analyst, 2014,139, 4491-4496
DOI: 10.1039/C4AN00807C, Paper

Simultaneous analysis of nanoparticles and small molecules by high-performance liquid chromatography using a silica monolithic column
Naoki Itoh, Akira Sano, Tomofumi Santa and Masaru Kato  
Analyst, 2014,139, 4453-4457
DOI: 10.1039/C4AN00819G, Communication

Parameters affecting ion intensities in transmission-mode direct analysis in real-time mass spectrometry
Lindsay P. Harding, Gareth M. B. Parkes and James D. Townend  
Analyst, 2014,139, 4176-4180
DOI: 10.1039/C4AN00859F, Communication

Simultaneous multiplexed quantification of nicotine and its metabolites using surface enhanced Raman scattering
Omar Alharbi, Yun Xu and Royston Goodacre  
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00879K, Paper

A graphene oxide-based enzyme-free signal amplification platform for homogeneous DNA detection
Zhen Zhang, Yufei Liu, Xinghu Ji, Xia Xiang and Zhike He  
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00933A, Paper

A spatiotemporally defined in vitro microenvironment for controllable signal delivery and drug screening
Ching-Te Kuo, Hao-Kai Liu, Guan-Syuan Huang, Chi-Hao Chang, Chen-Lin Chen, Ken-Chao Chen, Ruby Yun-Ju Huang, Ching-Hung Lin, Hsinyu Lee, Chiun-Sheng Huang and Andrew M. Wo  
Analyst, 2014, Advance Article
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Detection of strep throat causing bacterium directly from medical swabs by touch spray-mass spectrometry
Alan K. Jarmusch, Valentina Pirro, Kevin S. Kerian and R. Graham Cooks  
Analyst, 2014, Advance Article
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A rapid method to estimate the concentration of citrate capped silver nanoparticles from UV-visible light spectra
D. Paramelle, A. Sadovoy, S. Gorelik, P. Free, J. Hobley and D. G. Fernig  
Analyst, 2014, Advance Article
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Diagnosing malaria infected cells at the single cell level using focal plane array Fourier transform infrared imaging spectroscopy
Bayden R. Wood, Keith. R. Bambery, Matthew W. A. Dixon, Leann Tilley, Michael J. Nasse, Eric Mattson and Carol J. Hirschmugl  
Analyst, 2014, Advance Article
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A napthelene–pyrazol conjugate: Al(III) ion-selective blue shifting chemosensor applicable as biomarker in aqueous solution
Manjira Mukherjee, Siddhartha Pal, Somenath Lohar, Buddhadeb Sen, Supriti Sen, Samya Banerjee, Snehasis Banerjee and Pabitra Chattopadhyay  
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Microfluidic device with tunable post arrays and integrated electrodes for studying cellular release
Asmira Selimovic, Jayda L. Erkal, Dana M. Spence and R. Scott Martin  
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High efficiency tandem mass spectrometry analysis using dual linear ion traps
Linfan Li, Xiaoyu Zhou, James W. Hager and Zheng Ouyang  
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DOI: 10.1039/C4AN01070A, Communication

Detection of counterfeit electronic components through ambient mass spectrometry and chemometrics
Kevin P. Pfeuffer, Jack Caldwell, Jake T. Shelley, Steven J. Ray and Gary M. Hieftje  
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Hydroxylated near-infrared BODIPY fluorophores as intracellular pH sensors
Mohamed M. Salim, Eric A. Owens, Tielong Gao, Jeong Heon Lee, Hoon Hyun, Hak Soo Choi and Maged Henary  
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DOI: 10.1039/C4AN01104J, Paper

An inkjet-printed bioactive paper sensor that reports ATP through odour generation
Zhuyuan Zhang, Jingyun Wang, Robin Ng, Yingfu Li, Zaisheng Wu, Vincent Leung, Spencer Imbrogno, Robert Pelton, John D. Brennan and Carlos D. M. Filipe  
 Analyst, 2014, Advance Article
DOI: 10.1039/C4AN01113A, Communication

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