The 3Rs prize has been running since 2004, sponsored by GSK it is the annual prize of the National Centre for the Replacement, Refinement and Reduction of Animals in Research. It aims to highlight the best original contribution to science that benefits the 3Rs globally (to replace, reduce and refine the use of animals in research).
High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array
The paper from Shuichi Takayama, University of Michigan, USA, has been highly commended by the judges in this years 3Rs prize:
In his paper he describes a 3D cell culture used to test anti-cancer drugs, which was shown to be more representative of clinical responses than standard 2D ‘flat’ cell cultures. This new testing method has the potential to replace and reduce the use of animals in pharmaceutical testing.
Click on the link below to read this highly commended paper. It will be free to read until March 15th.
High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array
Yi-Chung Tung, Amy Y. Hsiao, Steven G. Allen, Yu-suke Torisawa, Mitchell Ho and Shuichi Takayama
Analyst, 2011, 136, 473-478
DOI: 10.1039/C0AN00609B
