Ion mobility-mass spectrometry measurements are regularly used in biological chemistry for many applications. This hot paper from Brandon Ruotolo and colleagues provides useful descriptions of important experimental parameters that affect ion mobility resolution and overall performance, and links this to theory. One referee commented that this will “be a very useful paper especially to students and researchers who will be using the new generation IM-MS instruments”.
Read the article for free until May 10th. Why not leave a comment below to let us know if you found the paper useful.
Characterizing the resolution and accuracy of a second-generation traveling-wave ion mobility separator for biomolecular ions
Yueyang Zhong, Suk-Joon Hyung and Brandon T. Ruotolo
Analyst
DOI: 10.1039/C0AN00987C
This paper will be included in a themed issue on Emerging Investigators, Guest Edited by Perdita Barran and Christy Haynes, to be published later this year.