Thomas Nugent and co-workers talk about the top organocatalysts for cyclic ketones and discover a 2-picolylamine template which is a promising new organocatalyst for aqueous aldol reactions.
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Picolylamine as an organocatalyst template for highly diastereo- and enantioselective aqueous aldol reactions
Thomas C. Nugent, M. Naveed Umar and Ahtaram Bibi
Org. Biomol. Chem., 2010, 8, 4085-4089
DOI: 10.1039/C0OB00049C