Chiral analysis continues to receive considerable attention since enantiomers often differ in their pharmacological activity and pharmacokinetic profile.
In this NJC letter, Haibing Li and co-workers from Central China Normal University at Wuhan (P.R. China) report a colorimetric sensor that displays a selective and strong response to L-histidine resulting from the agglomeration of silver nanoparticles. The authors believe that the self-assembly of nanoparticles into clusters is an effective approach to improve the sensitivity of chiral detection.
“Chiral colorimetric recognition of amino acids based on silver nanoparticle clusters” Yao Sun, Liang Zhang and Haibing Li, New J. Chem., 2012, Advance Article. DOI: 10.1039/C2NJ40098G.