RSC Medicinal Chemistry Blog

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Silver nanoparticles – the real “silver bullet” in clinical medicine? 
Kenneth K. Y. Wong and Xuelai Liu 
Med. Chem. Commun., 2010, 1, 125-131, DOI: 10.1039/C0MD00069H, Review 

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases
Elisabeth-Maria Bissinger, Ralf Heinke, Wolfgang Sippl and Manfred Jung  
Med. Chem. Commun., 2010, 1, 114-124, DOI: 10.1039/C0MD00062K, Review 

Discovery of the highly potent PI3K/mTOR dual inhibitor PF-04691502 through structure based drug design 
Hengmiao Cheng, Shubha Bagrodia, Simon Bailey, Martin Edwards, Jacqui Hoffman, Qiyue Hu, Robert Kania, Daniel R. Knighton, Matthew A. Marx, Sacha Ninkovic, Shaoxian Sun and Eric Zhang 
Med. Chem. Commun., 2010, 1, 139-144 , DOI: 10.1039/C0MD00072H, Concise Article 

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications 
Paul C. Trippier and Christopher McGuigan 
Med. Chem. Commun., 2010, 1, 183-198, DOI: 10.1039/C0MD00119H, Review 

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction 
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish 
Med. Chem. Commun., 2010, 1, 16-29, DOI: 10.1039/C0MD00055H, Review 

Synthesis and biological evaluation of novel ferrocenyl curcuminoid derivatives 
Anusch Arezki, Guy G. Chabot, Lionel Quentin, Daniel Scherman, Gérard Jaouen and Emilie Brulé 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C0MD00231C, Concise Article 

Chemical space as a source for new drugs 
Jean-Louis Reymond, Ruud van Deursen, Lorenz C. Blum and Lars Ruddigkeit 
Med. Chem. Commun., 2010, 1, 30-38, DOI: 10.1039/C0MD00020E, Review 

Novel indolizine compounds as potent inhibitors of phosphodiesterase IV (PDE4): structure-activity relationship 
Shoujun Chen, Zhiqiang Xia, Masazumi Nagai, Rongzhen Lu, Elena Kostik, Teresa Przewloka, Minghu Song, Dinesh Chimmanamada, David James, Shijie Zhang, Jun Jiang, Mitsunori Ono, Keizo Koya and Lijun Sun 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C0MD00215A, Concise Article 

Aromatic chloride to nitrile transformation: medicinal and synthetic chemistry 
Lyn H. Jones, Nicholas W. Summerhill, Nigel A. Swain and James E. Mills 
Med. Chem. Commun., 2010, 1, 309-318, DOI: 10.1039/C0MD00135J, Review 

Biofunctional TiO2 nanoparticle-mediated photokilling of cancer cells using UV irradiation 
Kazusa Matsui, Miki Karasaki, Maiko Segawa, Sang Youn Hwang, Tsutomu Tanaka, Chiaki Ogino and Akihiko Kondo 
Med. Chem. Commun., 2010, 1, 209-211, DOI: 10.1039/C0MD00027B, Concise Article 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to MedChemComm? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Silver nanoparticles – the real “silver bullet” in clinical medicine? 
Kenneth K. Y. Wong and Xuelai Liu 
Med. Chem. Commun., 2010, 1, 125-131, DOI: 10.1039/C0MD00069H, Review 

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications 
Paul C. Trippier and Christopher McGuigan 
Med. Chem. Commun., 2010, 1, 183-198, DOI: 10.1039/C0MD00119H, Review 

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction 
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish 
Med. Chem. Commun., 2010, 1, 16-29, DOI: 10.1039/C0MD00055H, Review 

Design, synthesis, and structure-activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists 
Julia M. Adam, Jim Cairns, Wilson Caulfield, Phillip Cowley, Iain Cumming, Morag Easson, Darren Edwards, Morag Ferguson, Richard Goodwin, Fiona Jeremiah, Takao Kiyoi, Ashvin Mistry, Elizabeth Moir, Richard Morphy, Jason Tierney, Mark York, James Baker, Jean E. Cottney, Andrea K. Houghton, Paul J. Westwood and Glenn Walker 
Med. Chem. Commun., 2010, 1, 54-60, DOI: 10.1039/C0MD00022A, Concise Article 

Aromatic chloride to nitrile transformation: medicinal and synthetic chemistry 
Lyn H. Jones, Nicholas W. Summerhill, Nigel A. Swain and James E. Mills 
Med. Chem. Commun., 2010, 1, 309-318, DOI: 10.1039/C0MD00135J, Review 

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases
Elisabeth-Maria Bissinger, Ralf Heinke, Wolfgang Sippl and Manfred Jung
Med. Chem. Commun., 2010, 1, 114-124, DOI: 10.1039/C0MD00062K, Review 

Chemical space as a source for new drugs 
Jean-Louis Reymond, Ruud van Deursen, Lorenz C. Blum and Lars Ruddigkeit 
Med. Chem. Commun., 2010, 1, 30-38, DOI: 10.1039/C0MD00020E, Review 

Discovery of the highly potent PI3K/mTOR dual inhibitor PF-04691502 through structure based drug design 
Hengmiao Cheng, Shubha Bagrodia, Simon Bailey, Martin Edwards, Jacqui Hoffman, Qiyue Hu, Robert Kania, Daniel R. Knighton, Matthew A. Marx, Sacha Ninkovic, Shaoxian Sun and Eric Zhang 
Med. Chem. Commun., 2010, 1, 139-144, DOI: 10.1039/C0MD00072H, Concise Article 

Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors 
Yen Ting Chen, Tomas Vojkovsky, Xingang Fang, Jennifer R. Pocas, Wayne Grant, Amiee M. W. Handy, Thomas Schröter, Philip LoGrasso, Thomas D. Bannister and Yangbo Feng 
Med. Chem. Commun., 2011, 2, 73-75, DOI: 10.1039/C0MD00194E, Concise Article 

Design, synthesis and biological evaluation of imidazopyridine/pyrimidine-chalcone derivatives as potential anticancer agents 
Ahmed Kamal, J. Surendranadha Reddy, M. Janaki Ramaiah, D. Dastagiri, E. Vijaya Bharathi, M. Victor Prem Sagar, S. N. C. V. L. Pushpavalli, Paramita Ray and Manika Pal-Bhadra 
Med. Chem. Commun., 2010, 1, 355-360, DOI: 10.1039/C0MD00116C, Concise Article 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to MedChemComm? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases 
Elisabeth-Maria Bissinger, Ralf Heinke, Wolfgang Sippl and Manfred Jung 
Med. Chem. Commun., 2010, 1, 114-124, DOI: 10.1039/C0MD00062K, Review 

Silver nanoparticles – the real “silver bullet” in clinical medicine? 
Kenneth K. Y. Wong and Xuelai Liu 
Med. Chem. Commun., 2010, 1, 125-131, DOI: 10.1039/C0MD00069H, Review 

Design, synthesis and biological evaluation of imidazopyridine/pyrimidine-chalcone derivatives as potential anticancer agents 
Ahmed Kamal, J. Surendranadha Reddy, M. Janaki Ramaiah, D. Dastagiri, E. Vijaya Bharathi, M. Victor Prem Sagar, S. N. C. V. L. Pushpavalli, Paramita Ray and Manika Pal-Bhadra 
Med. Chem. Commun., 2010, 1, 355-360, DOI: 10.1039/C0MD00116C, Concise Article 

Discovery of the highly potent PI3K/mTOR dual inhibitor PF-04691502 through structure based drug design 
Hengmiao Cheng, Shubha Bagrodia, Simon Bailey, Martin Edwards, Jacqui Hoffman, Qiyue Hu, Robert Kania, Daniel R. Knighton, Matthew A. Marx, Sacha Ninkovic, Shaoxian Sun and Eric Zhang 
Med. Chem. Commun., 2010, 1, 139-144, DOI: 10.1039/C0MD00072H, Concise Article 

Data-mining patent literature for novel chemical reagents for use in medicinal chemistry design 
Jason G. Kettle, Richard A. Ward and Ed Griffen 
Med. Chem. Commun., 2010, 1, 331-338, DOI: 10.1039/C0MD00148A, Concise Article 

Aromatic chloride to nitrile transformation: medicinal and synthetic chemistry 
Lyn H. Jones, Nicholas W. Summerhill, Nigel A. Swain and James E. Mills 
Med. Chem. Commun., 2010, 1, 309-318, DOI: 10.1039/C0MD00135J, Review 

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications 
Paul C. Trippier and Christopher McGuigan 
Med. Chem. Commun., 2010, 1, 183-198, DOI: 10.1039/C0MD00119H, Review 

Chemical space as a source for new drugs 
Jean-Louis Reymond, Ruud van Deursen, Lorenz C. Blum and Lars Ruddigkeit 
Med. Chem. Commun., 2010, 1, 30-38, DOI: 10.1039/C0MD00020E, Review 

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction 
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish 
Med. Chem. Commun., 2010, 1, 16-29, DOI: 10.1039/C0MD00055H, Review 

Impact of ion class and time on oral drug molecular properties 
Paul D. Leeson, Stephen A. St-Gallay and Mark C. Wenlock 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C0MD00157K, Review 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to MedChemComm? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Silver nanoparticles – the real “silver bullet” in clinical medicine? 
Kenneth K. Y. Wong and Xuelai Liu 
Med. Chem. Commun., 2010, 1, 125-131, DOI: 10.1039/C0MD00069H, Review  

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases 
Elisabeth-Maria Bissinger, Ralf Heinke, Wolfgang Sippl and Manfred Jung 
Med. Chem. Commun., 2010, 1, 114-124, DOI: 10.1039/C0MD00062K, Review  

Chemical space as a source for new drugs 
Jean-Louis Reymond, Ruud van Deursen, Lorenz C. Blum and Lars Ruddigkeit 
Med. Chem. Commun., 2010, 1, 30-38, DOI: 10.1039/C0MD00020E, Review  

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction 
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish 
Med. Chem. Commun., 2010, 1, 16-29, DOI: 10.1039/C0MD00055H, Review  

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications 
Paul C. Trippier and Christopher McGuigan 
Med. Chem. Commun., 2010, 1, 183-198, DOI: 10.1039/C0MD00119H, Review  

Discovery of the highly potent PI3K/mTOR dual inhibitor PF-04691502 through structure based drug design 
Hengmiao Cheng, Shubha Bagrodia, Simon Bailey, Martin Edwards, Jacqui Hoffman, Qiyue Hu, Robert Kania, Daniel R. Knighton, Matthew A. Marx, Sacha Ninkovic, Shaoxian Sun and Eric Zhang 
Med. Chem. Commun., 2010, 1, 139-144, DOI: 10.1039/C0MD00072H, Concise Article 

Data-mining patent literature for novel chemical reagents for use in medicinal chemistry design 
Jason G. Kettle, Richard A. Ward and Ed Griffen 
Med. Chem. Commun., 2010, 1, 331-338, DOI: 10.1039/C0MD00148A, Concise Article  

Design, synthesis, and structure-activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists 
Julia M. Adam, Jim Cairns, Wilson Caulfield, Phillip Cowley, Iain Cumming, Morag Easson, Darren Edwards, Morag Ferguson, Richard Goodwin, Fiona Jeremiah, Takao Kiyoi, Ashvin Mistry, Elizabeth Moir, Richard Morphy, Jason Tierney, Mark York, James Baker, Jean E. Cottney, Andrea K. Houghton, Paul J. Westwood and Glenn Walker 
Med. Chem. Commun., 2010, 1, 54-60, DOI: 10.1039/C0MD00022A, Concise Article  

Aromatic chloride to nitrile transformation: medicinal and synthetic chemistry 
Lyn H. Jones, Nicholas W. Summerhill, Nigel A. Swain and James E. Mills 
Med. Chem. Commun., 2010, 1, 309-318, DOI: 10.1039/C0MD00135J, Review  

Selective inhibition of EGFR and VEGFR2 tyrosine kinases controlled by a boronic acid substituent on 4-anilinoquinazolines 
Hiroyuki Nakamura, Ryoji Horikoshi, Taikou Usui and Hyun Seung Ban 
Med. Chem. Commun., 2010, 1, 282-286, DOI: 10.1039/C0MD00115E, Concise Article 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to MedChemComm? Then why not submit to us today or alternatively email us your suggestions.
 

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications 
Paul C. Trippier and Christopher McGuigan 
Med. Chem. Commun., 2010, 1, 183-198, DOI: 10.1039/C0MD00119H , Review 

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction 
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish 
Med. Chem. Commun., 2010, 1, 16-29, DOI: 10.1039/C0MD00055H , Review 

Antivascular and anticancer activity of dihalogenated A-ring analogues of combretastatin A-4 
Thomas M. Beale, Rebecca M. Myers, James W. Shearman, D. Stephen Charnock-Jones, James D. Brenton, Fanni V. Gergely and Steven V. Ley 
Med. Chem. Commun., 2010, 1, 202-208, DOI: 10.1039/C0MD00095G , Concise Article 

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases 
Elisabeth-Maria Bissinger, Ralf Heinke, Wolfgang Sippl and Manfred Jung 
Med. Chem. Commun., 2010, 1, 114-124, DOI: 10.1039/C0MD00062K , Review 

Effect of particle shape on phagocytosisof CdTe quantum dot–cystinecomposites 
Zhisong Lu, Yan Qiao, Xin Ting Zheng, Mary B. Chan-Park and Chang Ming Li 
Med. Chem. Commun., 2010, 1, 84-86, DOI: 10.1039/C0MD00008F , Concise Article 

Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists 
Glenn Walker et al 
Med. Chem. Commun., 2010, 1, 54-60, DOI: 10.1039/C0MD00022A , Concise Article 

Redesigning the designer drug ecstasy: non-psychoactive MDMA analogues exhibiting Burkitt’s lymphoma cytotoxicity 
Matthew J. Piggott et al 
Med. Chem. Commun., 2010, 1, 287-293, DOI: 10.1039/C0MD00108B , Concise Article 

Selective inhibition of EGFR and VEGFR2 tyrosinekinases controlled by a boronic acid substituent on 4-anilinoquinazolines 
Hiroyuki Nakamura, Ryoji Horikoshi, Taikou Usui and Hyun Seung Ban 
Med. Chem. Commun., 2010, 1, 282-286, DOI: 10.1039/C0MD00115E , Concise Article 

Silver nanoparticles—the real “silver bullet” in clinical medicine? 
Kenneth K. Y. Wong and Xuelai Liu 
Med. Chem. Commun., 2010, 1, 125-131, DOI: 10.1039/C0MD00069H , Review 

Synthesis and biological evaluation of substituted α- and β-2,3-dihydrofuran naphthoquinones as potent anticandidal agents 
Cristina Pessoa Veloso Freire, Sabrina Baptista Ferreira, Nivea Suely Melo de Oliveira, Ani Beatriz Jackisch Matsuura, Ivson Lelis Gama, Fernando de C. da Silva, Maria Cecília B. V. de Souza, Emerson Silva Lima and Vitor Francisco Ferreira 
Med. Chem. Commun., 2010, 1, 229-232, DOI: 10.1039/C0MD00074D , Concise Article 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to MedChemComm? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Discovery of the highly potent PI3K/mTOR dual inhibitor PF-04691502 through structure based drug design
Hengmiao Cheng, Shubha Bagrodia, Simon Bailey, Martin Edwards, Jacqui Hoffman, Qiyue Hu, Robert Kania, Daniel R. Knighton, Matthew A. Marx, Sacha Ninkovic, Shaoxian Sun and Eric Zhang
Med. Chem. Commun., 2010, 1, 139 – 144, DOI: 10.1039/c0md00072h, Concise Article

Silver nanoparticles-the real “silver bullet” in clinical medicine?
Kenneth K. Y. Wong and Xuelai Liu
Med. Chem. Commun., 2010, 1, 125 – 131, DOI: 10.1039/c0md00069h, Review article

Targeting epigenetic modifiers: Inhibitors of histone methyltransferases
Elisabeth-Maria Bissinger, Ralf Heinke, Wolfgang Sippl and Manfred Jung
Med. Chem. Commun., 2010, 1, 114 – 124, DOI: 10.1039/c0md00062k, Review article

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish
Med. Chem. Commun., 2010, 1, 16 – 29, DOI: 10.1039/c0md00055h, Review article

Syntheses and biological evaluation of new cephalosporin-oxazolidinone conjugates
Shanshan Yan, Marvin J. Miller, Timothy A. Wencewicz and Ute Mollmann
Med. Chem. Commun., 2010, 1, 145 – 148, DOI: 10.1039/c0md00015a, Concise article

Chemical space as a source for new drugs
Jean-Louis Reymond, Ruud van Deursen, Lorenz C. Blum and Lars Ruddigkeit
Med. Chem. Commun., 2010, 1, 30 – 38, DOI: 10.1039/c0md00020e, Review article

Cytotoxic sugar analogues of an optimized novobiocin scaffold
Alison C. Donnelly, Huiping Zhao, Bhaskar Reddy Kusuma and Brian S. J. Blagg
Med. Chem. Commun., 2010, 1, 165 – 170, DOI: 10.1039/c0md00063a, Concise article

Photografted poly(methyl methacrylate)-based high performance protein microarray for hepatitis B virus biomarker detection in human serum
Yingshuai Liu, Weihua Hu, Zhisong Lu and Chang Ming Li Med. Chem. Commun., 2010, 1, 132 – 135, DOI: 10.1039/c0md00032a, Concise article

Synthesis and biological evaluation of substituted alpha- and beta-2,3-dihydrofuran naphthoquinones as potent anticandidal agents
Cristina Pessoa Veloso Freire, Sabrina Baptista Ferreira, Nivea Suely Melo de Oliveira, Ani Beatriz Jackisch Matsuura, Ivson Lelis Gama, Fernando de C. da Silva, Maria Cecília B. V. de Souza, Emerson Silva Lima and Vitor Francisco Ferreira
Med. Chem. Commun., 2010, 1, 229 – 232, DOI: 10.1039/c0md00074d, Concise article

Synthesis, modeling, and crystallographic study of 3,4-disubstituted-1,2,5-oxadiazoles and evaluation of their ability to decrease STAT3 activity
Dae-Seop Shin, Daniela Masciocchi, Arianna Gelain, Stefania Villa, Daniela Barlocco, Fiorella Meneghetti, Alessandro Pedretti, Young-Min Han, Dong Cho Han, Byoung-Mog Kwon, Laura Legnani and Lucio Toma
Med. Chem. Commun., 2010, 1, 156 – 164, DOI: 10.1039/c0md00057d, Concise article

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to MedChemComm? Then why not submit to us today or alternatively email us your suggestions.

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Chemical space as a source for new drugs
Jean-Louis Reymond, Ruud van Deursen, Lorenz C. Blum and Lars Ruddigkeit
Med. Chem. Commun., 2010, 1, 30-38, DOI: 10.1039/C0MD00020E

Small molecule modulation of stem cells in regenerative medicine: recent applications and future direction
Timothy E. Allsopp, Mark E. Bunnage and Paul V. Fish
Med. Chem. Commun., 2010, 1, 16-29, DOI: 10.1039/C0MD00055H

Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists
Julia M. Adam, Jim Cairns, Wilson Caulfield, Phillip Cowley, Iain Cumming, Morag Easson, Darren Edwards, Morag Ferguson, Richard Goodwin, Fiona Jeremiah, Takao Kiyoi, Ashvin Mistry, Elizabeth Moir, Richard Morphy, Jason Tierney, Mark York, James Baker, Jean E. Cottney, Andrea K. Houghton, Paul J. Westwood and Glenn Walker
Med. Chem. Commun., 2010, 1, 54-60, DOI: 10.1039/C0MD00022A

Silver nanoparticles—the real “silver bullet” in clinical medicine?
Kenneth K. Y. Wong and Xuelai Liu
Med. Chem. Commun., 2010, 1, 125-131, DOI: 10.1039/C0MD00069H

An absolute structure template for a unique voltage-gated sodium channel binding site
Rex A. Palmer, Brian S. Potter, Michael J. Leach, Terence C. Jenkins and Babur Z. Chowdhry
Med. Chem. Commun., 2010, 1, 45-49, DOI: 10.1039/C0MD00043D

Synthesis and biological activity of new pyridonediaryl ether non-nucleoside inhibitorsof HIV-1 reverse transcriptase
Joshua J. Kennedy-Smith, Nidhi Arora, J. Roland Billedeau, Jennifer Fretland, Julie Q. Hang, Gabrielle M. Heilek, Seth F. Harris, Donald Hirschfeld, Hassan Javanbakht, Yu Li, Weiling Liang, Ralf Roetz, Mark Smith, Guoping Su, Judy M. Suh, Armando G. Villaseñor, Jeffrey Wu, Dennis Yasuda, Klaus Klumpp and Zachary K. Sweeney
Med. Chem. Commun., 2010, 1, 79-83, DOI: 10.1039/C0MD00009D

Histamine H3receptor ligands with a 3-cyclobutoxy motif: a novel and versatile constraint of the classical 3-propoxy linker
Maikel Wijtmans, Frédéric Denonne, Sylvain Célanire, Michel Gillard, Saskia Hulscher, Christel Delaunoy, Nathalie Van houtvin, Remko A. Bakker, Sabine Defays, Julien Gérard, Luc Grooters, Delphine Hubert, Henk Timmerman, Rob Leurs, Patrice Talaga, Iwan J. P. de Esch and Laurent Provins
Med. Chem. Commun., 2010, 1, 39-44, DOI: 10.1039/C0MD00056F

Effect of particle shape on phagocytosisof CdTe quantum dot–cystinecomposites
Zhisong Lu, Yan Qiao, Xin Ting Zheng, Mary B. Chan-Park and Chang Ming Li
Med. Chem. Commun., 2010, 1, 84-86, DOI: 10.1039/C0MD00008F

Synthesis and NMDAreceptor affinity of dexoxadrolanalogues with modifications in position 4 of the piperidine ring
Ashutosh Banerjee, Roland Fröhlich, Dirk Schepmann and Bernhard Wünsch
Med. Chem. Commun., 2010, 1, 87-102, DOI: 10.1039/C0MD00017E

Synthesis and selective inhibition of human monoamine oxidasesof a large scaffold of (4,5-substituted-thiazol-2-yl)hydrazones Franco Chimenti, Daniela Secci, Adriana Bolasco, Paola Chimenti, Arianna Granese, Simone Carradori, Melissa D’Ascenzio, Matilde Yáñez and Francisco Orallo
Med. Chem. Commun., 2010, 1, 61-72, DOI: 10.1039/C0MD00014K

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to MedChemComm? Then why not submit to us today or alternatively email us your suggestions.