This month sees the following articles in MedChemComm that are in the top ten most accessed:
Investigation of the effect of molecular properties on the binding kinetics of a ligand to its biological target
Duncan C. Miller, Graham Lunn, Peter Jones, Yogesh Sabnis, Nichola L. Davies and Paul Driscoll
Med. Chem. Commun., 2012, 3, 449-452
DOI: 10.1039/C2MD00270A
Epigenetics—an emerging and highly promising source of new drug targets
Nessa Carey
Med. Chem. Commun., 2012, 3, 162-166
DOI: 10.1039/C1MD00264C
Minisci reactions: Versatile CH-functionalizations for medicinal chemists
Matthew A. J. Duncton
Med. Chem. Commun., 2011, 2, 1135-1161
DOI: 10.1039/C1MD00134E
Inhibition of bromodomain-mediated protein–protein interactions as a novel therapeutic strategy
Silviya D. Furdas, Luca Carlino, Wolfgang Sippl and Manfred Jung
Med. Chem. Commun., 2012, 3, 123-134
DOI: 10.1039/C1MD00201E
Development of second generation epigenetic agents
Philip Jones
Med. Chem. Commun., 2012, 3, 135-161
DOI: 10.1039/C1MD00199J
Rhodanine carboxylic acids as novel inhibitors of histone acetyltransferases
Silviya D. Furdas, Suhaib Shekfeh, Srinivasaraghavan Kannan, Wolfgang Sippl and Manfred Jung
Med. Chem. Commun., 2012, 3, 305-311
DOI: 10.1039/C2MD00211F
Small-molecule inhibitors of dimeric transcription factors: Antagonism of protein–protein and protein–DNA interactions
Jeremy L. Yap, Jay Chauhan, Kwan-Young Jung, Lijia Chen, Edward V. Prochownik and Steven Fletcher
Med. Chem. Commun., 2012, Advance Article
DOI: 10.1039/C2MD00289B
Towards biocompatible nanovalves based on mesoporous silica nanoparticles
Ying-Wei Yang
Med. Chem. Commun., 2011, 2, 1033-1049
DOI: 10.1039/C1MD00158B
Molecular obesity, potency and other addictions in drug discovery
Michael M. Hann
Med. Chem. Commun., 2011, 2, 349-355
DOI: 10.1039/C1MD00017A
SAR mining and its application to the design of TRPA1 antagonists
James E. J. Mills, Alan D. Brown, Thomas Ryckmans, Duncan C. Miller, Sarah E. Skerratt, Carolyn M. Barker and Mark E. Bunnage
Med. Chem. Commun., 2012, 3, 174-178
DOI: 10.1039/C1MD00213A
Why not take a look at the articles today and blog your thoughts and comments below.
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