Bio-polymer/silica composites for drug delivery and synthetic lung surfactants on the cover of Issue 12

Welcome to the final issue of 2011!

On the outside front cover of this issue is an article from Chang-Sik Ha and coworkers on a one step synthetic route to a hierarchical mesoporous bio-polymer/silica composite material with bimodal mesopores using a dual template of N,N,N-trimethyl chitosan (TMCs) and sodium dodecyl sulfate (SDS) for pH-sensitive targeted drug release.

Hierarchical mesoporous bio-polymer/silica composites co-templated by trimethyl chitosan and a surfactant for controlled drug delivery
Vijay Kumar Rana, Sung Soo Park, Surendran Parambadath, Mi Ju Kim, Sun-Hee Kim, Satyendra Mishra, Raj Pal Singh and Chang-Sik Ha
DOI: 10.1039/C0MD00222D

On the inside front cover Adrian Schwan et al. report a a novel phospholipase-resistant C16:0, C16:1 diether phosphonoglycerol as a synthetic lung surfactant with surface activity equivalent to calf lung surfactant extract.

Synthesis and activity of a novel diether phosphonoglycerol in phospholipase-resistant synthetic lipid:peptide lung surfactants
Adrian L. Schwan, Suneel P. Singh, Jason A. Davy, Alan J. Waring, Larry M. Gordon, Frans J. Walther, Zhengdong Wang and Robert H. Notter
DOI: 10.1039/C1MD00206F

As with all our cover articles these are free to access for 6 weeks.

View the rest of the issue here

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