This review article from Mercedes Álvarez and colleagues at The Center for Biomedical Research Network in Bioengineering, Biomaterials and Nanomedicine, Barcelona, have reviewed the recent developments in studies on lamellarins and their analogues.
Lamellarins are a family of marine pyrrole alkaloids, which have attracted interest as anti-tumour agents. The review encompasses synthetic strategies for total synthesis, structure–activity relationships and studies on mechanisms of biological action, mainly in the context of anti-tumor activity.
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Progress on lamellarins
Daniel Pla, Fernando Albericio and Mercedes Álvarez
Med. Chem. Commun., 2011, Advance Article
DOI: 10.1039/C1MD00003A
