Top ten most accessed articles in April

This month sees the following articles in MedChemComm that are in the top ten most accessed:-

Molecular obesity, potency and other addictions in drug discovery 
Michael M. Hann 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C1MD00017A, Review 

Aromatic chloride to nitrile transformation: medicinal and synthetic chemistry 
Lyn H. Jones, Nicholas W. Summerhill, Nigel A. Swain and James E. Mills 
Med. Chem. Commun., 2010, 1, 309-318, DOI: 10.1039/C0MD00135J  

Identification of target family directed bioisosteric replacements
Anne Mai Wassermann and Jürgen Bajorath 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C1MD00066G  

The p53-MDM2/MDMX axis – A chemotype perspective 
Kareem Khoury, Grzegorz M. Popowicz, Tad A. Holak and Alexander Dömling 
Med. Chem. Commun., 2011, 2, 246-260, DOI: 10.1039/C0MD00248H, Review 

Platinum-oxazoline complexes as anti-cancer agents: syntheses, characterisation and initial biological studies 
Paras N. Yadav, Ramsay E. Beveridge, Jonathan Blay, Alaina R. Boyd, Maja W. Chojnacka, Andreas Decken, Ankur A. Deshpande, Michael G. Gardiner, Trevor W. Hambley, Michael J. Hughes, Leslie Jolly, Jacquelyn A. Lavangie, Timothy D. MacInnis, Sherri A. McFarland, Elizabeth J. New and Robert A. Gossage 
Med. Chem. Commun., 2011, 2, 274-277, DOI: 10.1039/C0MD00211A  

Natural products targeting telomere maintenance 
Jack Li-Yang Chen, Jonathan Sperry, Nancy Y. Ip and Margaret A. Brimble 
Med. Chem. Commun., 2011, 2, 229-245, DOI: 10.1039/C0MD00241K  

(Carboxydiamine)Pt(ii) complexes of a combretastatin A-4 analogous chalcone: the influence of the diamine ligand on DNA binding and anticancer effects 
Miroslava Zoldakova, Bernhard Biersack, Hana Kostrhunova, Aamir Ahmad, Subhash Padhye, Fazlul H. Sarkar, Rainer Schobert and Viktor Brabec 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C1MD00042J  

Synthesis and biological evaluation of tetrazole containing compounds as possible anticancer agents 
Chebolu Naga Sesha Sai Pavan Kumar, Dusmant Kumar Parida, Amlipur Santhoshi, Anil Kumar Kota, Balasubramanian Sridhar and Vaidya Jayathirtha Rao 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C0MD00263A 

Synthesis and efficient siRNA delivery of polyamine-conjugated cationic nucleoside lipids 
Sachin Prakash Patil, Jeong Wu Yi, Eun-Kyoung Bang, Eun Mi Jeon and Byeang Hyean Kim 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C1MD00014D  

N-(5-substituted thiazol-2-yl)-2-aryl-3-(tetrahydro-2H-pyran-4-yl) propanamides as glucokinase activators 
Zhiqing Liu, Qingzhang Zhu, Fuying Li, Lina Zhang, Ying Leng and Ao Zhang 
Med. Chem. Commun., 2011, Advance Article, DOI: 10.1039/C1MD00002K  

Why not take a look at the articles today and blog your thoughts and comments below.

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