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Moving microrobots with bubbles

Microrobots smaller than the width of a human hair have been directed to assemble patterns made of single yeast cells and cell-laden agarose microgels using cavitation bubbles by a team from Hawaii. The robots could be used to push cells together to grow artificial tissue.

The microbot manipulating agarose gel blocks, some containing cells, into a 3x4 array

The microbot manipulating agarose gel blocks, some containing cells, into a 3x4 array

There have been a number of different methods used to manipulate single cells into patterns; including micromanipulators, which physically trap and hold cells but need skilled technicians to use them; and optical tweezers, which can be automated but usually need strong lasers or electrical fields that can affect the cells.

Read the full article in Chemistry World.

Or read the Lab on a Chip paper:
Hydrogel microrobots actuated by optically generated vapour bubbles
Wenqi Hu, Kelly S. Ishii, Qihui Fan and Aaron T. Ohta
Lab Chip, 2012,12, 3821-3826
DOI: 10.1039/C2LC40483D

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New YouTube videos

View the new videos on the Lab on a Chip YouTube site using the links below:

Gelatin methacrylate as a promising hydrogel for 3D microscale organization and proliferation of dielectrophoretically patterned cells

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Towards a high-throughput label-free detection system combining localized-surface plasmon resonance and microfluidics

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Dissolution-guided wetting for microarray and microfluidic devices

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Blood separation on microfluidic paper-based analytical devices

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Microfluidic cell volume sensor with tunable sensitivity

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An integrated fiber-optic microfluidic device for detection of muscular force generation of microscopic nematodes

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