Congratulations to the authors!
Read the articles on Science Daily, PhysOrg.com and nanowerk.com or go straight to the Lab on a Chip paper:
Increasing the detection speed of an all-electronic real-time biosensor
Matthew R. Leyden , Robert J. Messinger , Canan Schuman , Tal Sharf , Vincent T. Remcho , Todd M. Squires and Ethan D. Minot
DOI: 10.1039/C2LC21020G
If you’ve missed any of the previous articles take a look at the web collection here.
A multifunctional pipette
Alar Ainla, Gavin D. M. Jeffries, Ralf Brune, Owe Orwar and Aldo Jesorka
DOI: 10.1039/C2LC20906C
Engineers are from PDMS-land, Biologists are from Polystyrenia
Erwin Berthier, Edmond W. K. Young and David Beebe
DOI: 10.1039/C2LC20982A
Another HOT article in this issue is by Serge G. Lemay and colleagues at the MESA+ Institute for Nanotechnology, University of Twente, reporting on their study of the response time of nanofluidic thin-layer cells as electrochemical sensors, and suggested means of improving that time.
Response time of nanofluidic electrochemical sensors
Shuo Kang, Klaus Mathwig and Serge G. Lemay
DOI: 10.1039/C2LC21104A
This issue also features the latest article in our Acoustofluidics series, by Thomas Laurell and colleagues at Lund University, Applications of acoustophoresis in continuous flow microsystems; and our latest Research Highlights from Ali Khademhosseini and colleagues.
As usual, all our HOT articles are free to access for four weeks (following a simple registration for individual users).
Micro-immunohistochemistry using a microfluidic probe
Robert D. Lovchik, Govind V. Kaigala, Marios Georgiadis and Emmanuel Delamarche
DOI: 10.1039/C2LC21016A
A self-loading microfluidic device for determining the minimum inhibitory concentration of antibiotics
Nate J. Cira, Jack Y. Ho, Megan E. Dueck and Douglas B. Weibel
DOI: 10.1039/C2LC20887C
The issue also includes the Focus article ‘Standards for collecting microfluidic devices?‘ by Henne van Heeren at enablingMNT, discussing the need for standards for microfluidic interconnections, chip dimensions and a vocabulary, the latest article in our Acoustofluidics series on the acoustic radiation force on small particles by Henrik Bruus at the Technical University of Denmark, and the following HOT articles:
Sorting cells by size, shape and deformability
Jason P. Beech, Stefan H. Holm, Karl Adolfsson and Jonas O. Tegenfeldt
DOI: 10.1039/C2LC21083E
A microfluidic method to study demulsification kinetics
Thomas Krebs, Karin Schroen and Remko Boom
DOI: 10.1039/C2LC20930F
Design considerations for electrostatic microvalves with applications in poly(dimethylsiloxane)-based microfluidics
Amit V. Desai, Joshua D. Tice, Christopher A. Apblett and Paul J. A. Kenis
DOI: 10.1039/C2LC21133E
All our HOT articles are free to access for four weeks (following a simple registration for individual users).
During 2011 we published a number of topical reviews on a wide range of topics by expert researchers in their fields. We’ve collected some of them below but take a look here for the whole list, we hope you’ll find something interesting in your area.
Miles Padgett and Roberto Di Leonardo
Lab-on-a-chip based immunosensor principles and technologies for the detection of cardiac biomarkers: a review
Mazher-Iqbal Mohammed and Marc P. Y. Desmulliez
Nanomanipulation using near field photonics
David Erickson, Xavier Serey, Yih-Fan Chen and Sudeep Mandal
Microfluidics for food, agriculture and biosystems industries
Suresh Neethirajan, Isao Kobayashi, Mitsutoshi Nakajima, Dan Wu, Saravanan Nandagopal and Francis Lin
Hyundoo Hwang and Je-Kyun Park
Disposable microfluidic substrates: Transitioning from the research laboratory into the clinic
Jason S. Kuo and Daniel T. Chiu
Miniaturized isothermal nucleic acid amplification, a review
Peter J. Asiello and Antje J. Baeumner
If you have an idea for a review article that hasn’t been covered and you would like to see included, contact the Editorial Office – we’d love to hear from you.
Fully automated cellular-resolution vertebrate screening platform with parallel animal processing
Tsung-Yao Chang, Carlos Pardo-Martin, Amin Allalou, Carolina Wählby and Mehmet Fatih Yanik
DOI: 10.1039/C1LC20849G
Microfabricated passive vapor preconcentrator/injector designed for microscale gas chromatography
Jung Hwan Seo, Sun Kyu Kim, Edward T. Zellers and Katsuo Kurabayashi
DOI: 10.1039/C2LC20932B
The issue also features a whole host of hot articles on topics from education to droplets, which will be free to access for 4 weeks:
Education: a microfluidic platform for university-level analytical chemistry laboratories
Jesse Greener, Ethan Tumarkin, Michael Debono, Andrew P. Dicks and Eugenia Kumacheva
DOI: 10.1039/C2LC20951A
Self-propelling surfactant droplets in chemically-confined microfluidics – cargo transport, drop-splitting and trajectory control
David K. N. Sinz and Anton A. Darhuber
DOI: 10.1039/C2LC21082G
Droplet-based microfluidic device for multiple-droplet clustering
Jing Xu, Byungwook Ahn, Hun Lee, Linfeng Xu, Kangsun Lee, Rajagopal Panchapakesan and Kwang W. Oh
DOI: 10.1039/C2LC20883K
Quick genotyping detection of HBV by giant magnetoresistive biochip combined with PCR and line probe assay
Xiao Zhi, Qingsheng Liu, Xin Zhang, Yixia Zhang, Jie Feng and Daxiang Cui
DOI: 10.1039/C2LC20949G
Rapid prototyping of three-dimensional microfluidic mixers in glass by femtosecond laser direct writing
Yang Liao, Jiangxin Song, En Li, Yong Luo, Yinglong Shen, Danping Chen, Ya Cheng, Zhizhan Xu, Koji Sugioka and Katsumi Midorikawa
DOI: 10.1039/C2LC21015K
Ultrahigh sensitivity assays for human cardiac troponin I using TiO2 nanotube arrays
Piyush Kar, Archana Pandey, John J. Greer and Karthik Shankar
DOI: 10.1039/C2LC20892J
Also, take a look at the latest article in our acoustofluidics series – Building microfluidic acoustic resonators.
Chips & Tips has a shiny new Facebook page!
Chips & Tips is our forum for discussing common practical problems encountered in miniaturisation labs, which are seldom reported in the literature. Check out the regularly updated blog at https://blogs.rsc.org/chipsandtips/, or visit Facebook and like us to join the discussion – we’d love to hear your tips for chips!
The recent LOC article from Douglas Weibel and team at the University of Wisconsin-Madison has been highlighted on MedGadget. The article describes a new portable self-loading technology for determining minimum inhibitory concentration values, vital in clinical bacteriology for determining whether an organism is reported susceptible or resistant.
Congratulations to Douglas Weibel and team!
You can read the MedGadget article online here or go straight to the Lab on a Chip paper:
A self-loading microfluidic device for determining the minimum inhibitory concentration of antibiotics
Nate J. Cira, Jack Y. Ho, Megan E. Dueck and Douglas B. Weibel
Lab Chip, 2012, Advance Article
DOI: 10.1039/C2LC20887C
Acoustofluidics 1: Governing equations in microfluidics
Henrik Bruus
DOI: 10.1039/C1LC20658C
Acoustofluidics 2: Perturbation theory and ultrasound resonance modes
Henrik Bruus
DOI: 10.1039/C1LC20770A
Acoustofluidics 3: Continuum mechanics for ultrasonic particle manipulation
Jurg Dual and Thomas Schwarz
DOI: 10.1039/C1LC20837C
Acoustofluidics 4: Piezoelectricity and application in the excitation of acoustic fields for ultrasonic particle manipulation
Jurg Dual and Dirk Möller
DOI: 10.1039/C1LC20913B
Don’t forget to check back soon for more articles in this exciting new area and if you have any comments on the series so far we’d love to hear them!
Last week the Wyss Institute for Biologically Inspired Engineering at Harvard University awarded its Founding Director and Lab on a Chip Editorial Board member, Donald Ingber, M.D., Ph.D., the 2011 Holst Medal in recognition of his pioneering work exploring the cellular mechanisms that contribute to mechanical control of tissue and organ development, and his groundbreaking development of bioinspired technologies, ranging from organ-on-chip replacements for animal studies, to new engineering approaches for whole organ engineering.
The award was presented on December 16th at the High Tech Campus Eindhoven in the Netherlands during a ceremony at the close of the 2011 Holst Symposium, which focused on integrated heart repair. As the medal winner, Ingber also presented the 2011 Holst Memorial Lecture entitled “From Cellular Mechanotransduction to Organ Engineering.” Starting with an exploration of the role that cell structure and mechanics play in controlling tissue and organ development, Ingber’s lecture extended to provide a more comprehensive overview of his most recent innovations, including development of organ-on-chip microsystems technologies that recapitulate human organ functions, bioinspired materials that promote whole tooth organ formation, and injectable programmable nanotherapeutics that restore blood flow to occluded blood vessels.
“Donald Ingber has made groundbreaking contributions to the understanding of the mechanobiology of cellular behavior,” said Joep Huiskamp, Secretary of the Holst Memorial Lecture Award Committee 2011, on its behalf. “Ingber’s recent development of a breathing lung-on-a-chip concept is an outstanding example of convergent technologies.”
This year’s Holst events were dedicated to the global health issue of heart disease, in recognition of its enormous emotional, medical, economical, and societal implications. The symposium brought together a few select leading international experts, including Wyss Institute core faculty member Kevin Kit Parker, Ph.D., to discuss key facets of heart disease, regeneration, and repair. Parker’s work on engineering heart tissues recently featured on the Issue 24 cover of Lab on a Chip (see Ensembles of engineered cardiac tissues for physiological and pharmacological study: Heart on a chip).
Donald Ingber, together with Lab on a Chip Chair George Whitesides, will be guest editor of our final 10th Anniversary issue focusing on the USA which has the theme of translating research from the lab to the clinic, to be published next year.
Adapted from the Wyss Institute press release
