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Highly focused high-frequency travelling surface acoustic waves (SAW) for rapid single-particle sorting

Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels

Programmable V-type Valve for Cell and Particle Manipulation in Microfluidic Devices

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Controllable Generation and Encapsulation of Alginate Fibers Using Droplet-Based Microfluidics

Digital Droplet PCR on Disk

3D cardiac µtissues within a microfluidic device with real-time contractile stress readout

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Microscopic pumps made from trapped bacteria

Scientists in China have trapped bacteria in 3D-printed structures and used them to pump materials along customised paths.

Transporting materials in the microscopic world is complex. Conventionally, macroscopic pumps drive motion, but pumps are bulky and not ideal for miniaturisation. Now, Hepeng Zhang and colleagues at Shanghai Jiao Tong University have tackled this problem using native inhabitants of the microscopic world – motile bacteria. Not only are they already present in the media, but their energy conversion efficiency is estimated to be greater than existing man-made micro-motors.

Please visit Chemistry World to read the full article.

Using confined bacteria as building blocks to generate fluid flow
Zhiyong Gao, He Li, Xiao Chen and H. P. Zhang
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC01093D

*Access is free through a registered RSC account until 10 December 2015 – click here to register
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Microfluidic device lets the drop beat

Scientists in Switzerland have incorporated pulsing human heart tissue into a microfluidic device to make a miniscule model of a living system that could be used to test new drugs.

The hanging drops are connected through 200μm-wide channels

‘This is one of the most interesting recent developments in the field of microfluidic systems,’ comments Wouter van der Wijngaart, who heads up the research into micro- and nanofluidic systems at the KTH Royal Institute of Technology in Sweden. ‘This type of system has the potential to become the de facto workhorse in the field of 3D microtissue culturing.’

Please visit Chemistry World to read the full article.

Adding the ‘heart’ to hanging drop networks for microphysiological multi-tissue experiments*
Saeed Rismani Yazdi, Amir Shadmani, Sebastian C. Bürgel, Patrick M. Misun, Andreas Hierlemann and Olivier Frey
Lab Chip, 2015, Advance Article
DOI: 10.1039/C5LC01000D

*Access is free through a registered RSC account until 19 November 2015 – click here to register

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New YouTube Videos!

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Top 10 most accessed Lab on a Chip articles in June 2015

In June 2015, our most downloaded Lab on a Chip articles were:

Shia-Yen Teh, Robert Lin, Lung-Hsin Hung and Abraham P. Lee
DOI: 10.1039/B715524G

Ali Kemal Yetisen, Muhammad Safwan Akram and Christopher R. Lowe
DOI: 10.1039/C3LC50169H

Russell H. Cole, Niek de Lange, Zev J. Gartner and Adam R. Abate
DOI: 10.1039/C5LC00333D

Ching-Hui Lin, Yi-Hsing Hsiao, Hao-Chen Chang, Chuan-Feng Yeh, Cheng-Kun He, Eric M. Salm, Chihchen Chen, Ing-Ming Chiu and Chia-Hsien Hsu
DOI: 10.1039/C5LC00541H

Friedrich Schuler, Frank Schwemmer, Martin Trotter, Simon Wadle, Roland Zengerle, Felix von Stetten and Nils Paust
DOI: 10.1039/C5LC00291E

Mei He, Jennifer Crow, Marc Roth, Yong Zeng and Andrew K. Godwin
DOI: 10.1039/C4LC00662C

Joost F. Swennenhuis, Arjan G. J. Tibbe, Michiel Stevens, Madhumohan R. Katika, Joost van Dalum, Hien Duy Tong, Cees J. M. van Rijn and Leon W. M. M. Terstappen
DOI: 10.1039/C5LC00304K

A. Liga, A. D. B. Vliegenthart, W. Oosthuyzen, J. W. Dear and M. Kersaudy-Kerhoas
DOI: 10.1039/C5LC00240K

A. Wasay and D. Sameoto
DOI: 10.1039/C5LC00342C

Ivo Leibacher, Peter Reichert and Jürg Dual
DOI: 10.1039/C5LC00083A

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