Congratulations go to Chang Lu at the School of Biomedical Engineering and Sciences at Virginia Tech has been awarded a new National Institutes of Health project to continue his work with Albert Baldwin at The University of North Carolina on the molecular mechanisms of cancer.
Preliminary work by Chang Lu and co-workers published in Lab on a Chip in 2011 focused on histone modification analysis using a microfluidic platform. Their microfluidics device enables traditional chromatin immunoprecipitation assays (ChIP) using much lower numbers of cells in a much quicker time. All steps are conducted on-chip. The assay is coupled with RT-PCR to give a speedier method for analysis of scarce biological samples.
This new grant from the NIH is to continue this work in designing more advanced, more sensitive on-chip ChIP assays as part of the institutes’ National Cancer Initiative.
Read the first paper in Lab on a Chip today:
Histone modification analysis by chromatin immunoprecipitation from a low number of cells on a microfluidic platform
Tao Geng, Ning Bao, Michael D. Litt, Trevor G. Glaros, Liwu Lid and Chang Lu
DOI: 10.1039/C1LC20253G
