On the outside front cover is a Technical Innovation from Oliver Hayden, Michael Helou and co-workers in Germany describing a magnetic time-of-flight flow cytometry workflow for point-of-care tests, integrating sample preparation with the use of superparamagnetic labels:
Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation
Michael Helou, Mathias Reisbeck, Sandro F. Tedde, Lukas Richter, Ludwig Bär, Jacobus J. Bosch, Roland H. Stauber, Eckhard Quandt and Oliver Hayden
DOI: 10.1039/C3LC41310A
The inside front cover highlights work by Martin Gijs’s team at EPFL, Switzerland, on a microfluidic method for ultra-sensitive protein detection in serum using magnetic beads:
Attomolar protein detection using a magnetic bead surface coverage assay
H. Cumhur Tekin, Matteo Cornaglia and Martin A. M. Gijs
DOI: 10.1039/C3LC41285G
Mengsu Yang and co-workers at the City University of Hong Kong are advertised on the back cover, which illustrates their research on monitoring of intracellular calcium signals after mechanical stimulation using a single integrated microfluidic device:
Microfluidics study of intracellular calcium response to mechanical stimulation on single suspension cells
Tao Xu, Wanqing Yue, Cheuk-Wing Li, Xinsheng Yao and Mengsu Yang
DOI: 10.1039/C3LC40880A
Remember, all of our cover articles are free to access for 6 weeks!*
The final paper in our highly interesting Acoustofluidics series of tutorial articles is published in Issue 6. It points out the ability to combine acoustic forces with others for microfluidic applications:
Acoustofluidics 23: acoustic manipulation combined with other force fields
Peter Glynne-Jones and Martyn Hill
DOI: 10.1039/C3LC41369A
Issue 6 also includes a Critical Review on sample preparation for cell analysis technology from Dino Di Carlo et al. at the University of California, USA:
Microfluidic sample preparation for diagnostic cytopathology
Albert J. Mach, Oladunni B. Adeyiga and Dino Di Carlo
DOI: 10.1039/C2LC41104K
HOT articles in Issue 6 include:
On-chip microrobot for investigating the response of aquatic microorganisms to mechanical stimulation
Tomohiro Kawahara, Masakuni Sugita, Masaya Hagiwara, Fumihito Arai, Hiroyuki Kawano, Ikuko Shihira-Ishikawa and Atsushi Miyawaki
DOI: 10.1039/C2LC41190C
Dynamic pH mapping in microfluidic devices by integrating adaptive coatings based on polyaniline with colorimetric imaging techniques
Larisa Florea, Cormac Fay, Emer Lahiff, Thomas Phelan, Noel E. O’Connor, Brian Corcoran, Dermot Diamond and Fernando Benito-Lopez
DOI: 10.1039/C2LC41065F
For more fascinating Lab on a Chip content, read the full issue here
