LOC issue 8 available now

Issue 8 is now available online, and the front cover features a HOT communication from Sungyoung Choi, Jeffrey M. Karp and Rohit Karnik at the Massachusetts Institute of Technology, Cambridge, USA. The article demonstrates the group’s use of deterministic cell rolling to sort cells in a label-free, gentle manner.

Cell sorting by deterministic cell rolling
Sungyoung Choi, Jeffrey M. Karp and Rohit Karnik
DOI: 10.1039/C2LC21225K

The inside front cover features a HOT paper from Chang Lu and colleagues, which outlines the group’s use of total internal reflection fluorescence flow cytometry (TIRF-FC) to quantitatively measure quantum dot uptake into cells at a single cell level.

Quantitative measurement of quantum dot uptake at the cell population level using microfluidic evanescent-wave-based flow cytometry
Jun Wang, Yihong Zhan, Ning Bao and Chang Lu
DOI: 10.1039/C2LC21298F

Other HOT papers in the issue include:

Microfluidics meets soft layer-by-layer films: selective cell growth in 3D polymer architectures
Narayanan Madaboosi, Katja Uhlig, Stephan Schmidt, Magnus S. Jäger, Helmuth Möhwald, Claus Duschl and Dmitry V. Volodkin
DOI: 10.1039/C2LC40058H

Gene-Z: a device for point of care genetic testing using a smartphone
Robert D. Stedtfeld, Dieter M. Tourlousse, Gregoire Seyrig, Tiffany M. Stedtfeld, Maggie Kronlein, Scott Price, Farhan Ahmad, Erdogan Gulari, James M. Tiedje and Syed A. Hashsham
DOI: 10.1039/C2LC21226A

DNA electrophoresis in a nanofence array
Sung-Gyu Park, Daniel W. Olson and Kevin D. Dorfman
DOI: 10.1039/C2LC00016D

Also in this issue is the ninth instalment of our Acoustofluidics series – this issue’s article focuses on the design, construction and applications of planar resonant devices for acoustic manipulation of particles and cells.

Acoustofluidics 9: Modelling and applications of planar resonant devices for acoustic particle manipulation
Peter Glynne-Jones, Rosemary J. Boltryk and Martyn Hill
DOI: 10.1039/C2LC21257A

Finally, this issue sees the start of a new Focus article series from Tony Jun Huang that will discuss bio-related issues that impact on lab on a chip and microfluidic research. The first article focuses on microfluidic devices for diagnostics in the developing world.

Microfluidic diagnostics for the developing world
Xiaole Mao and Tony Jun Huang
DOI:10.1039/C2LC90022J

Read the rest of issue 8 now!

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