On the front cover of Issue 19 is an article from Aaron Wheeler et al. on their new method for the analysis of dried blood spot samples. The method has the potential to offer automation of dried blood samples, which are useful for a number of clinical and pharmaceutical applications due to the small sample sizes involved and ease of storage. The team have developed a prototype microfluidic system to quantify amino acids in which analytes are extracted, mixed with internal standards, derivatized, and reconstituted for analysis by tandem mass spectrometry.
This hot article was also recently reported on in C&EN.
A digital microfluidic method for dried blood spot analysis
Mais J. Jebrail, Hao Yang, Jared M. Mudrik, Nelson M. Lafrenière, Christine McRoberts, Osama Y. Al-Dirbashi, Lawrence Fisher, Pranesh Chakraborty and Aaron R. Wheeler
Lab Chip, 2011, 11, 3218-3224
DOI: 10.1039/C1LC20524B
