This month’s issue features another great selection of articles, including a Focus article from Mathias Uhlen and Helene Andersson Svahn on affinity reagents for lab on a chip applications.
Featured on the outside front cover is the HOT article from William Rodriguez and Rashid Bashir et al., demonstrating a microfabricated biochip to determine the CD4+ T lymphocyte count in HIV patients.
A microfabricated electrical differential counter for the selective enumeration of CD4+ T lymphocytes
Nicholas N. Watkins, Supriya Sridhar, Xuanhong Cheng, Grace D. Chen, Mehmet Toner, William Rodriguez and Rashid Bashir
On the inside front cover we have Rodolphe Marie’s micro device that can isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. This paper was recently featured in Chemistry World – you can read the story here.
A device for extraction, manipulation and stretching of DNA from single human chromosomes
Kristian H. Rasmussen, Rodolphe Marie, Jacob M. Lange, Winnie E. Svendsen, Anders Kristensen and Kalim U. Mir
Finally, the back cover highlights work from Gang Logan Liu, using a standard CD drive to count microparticles and cells with a digital microfluidic compact disc. This article was also recently highlighted in Chemistry World.
Microparticle and cell counting with digital microfluidic compact disc using standard CD drive
Syed M. Imaad, Nathan Lord, Gulsim Kulsharova and Gang Logan Liu
Other HOT articles in this issue include:
Integrated photocatalytic micropillar nanoreactor electrospray ionization chip for mimicking phase I metabolic reactions
Teemu Nissilä, Lauri Sainiemi, Mika-Matti Karikko, Marianna Kemell, Mikko Ritala, Sami Franssila, Risto Kostiainen and Raimo A. Ketola
Capillary-driven automatic packaging
Yuzhe Ding, Lingfei Hong, Baoqing Nie, Kit S. Lam and Tingrui Pan
A magnetic bead-based assay for the rapid detection of methicillin-resistant Staphylococcus aureus by using a microfluidic system with integrated loop-mediated isothermal amplification
Chih-Hung Wang, Kang-Yi Lien, Jiunn-Jong Wu and Gwo-Bin Lee