Archive for January, 2011

Top ten most accessed articles in December

This month sees the following articles in Lab on a Chip that are in the top ten most accessed:-

Simple room temperature bonding of thermoplastics and poly(dimethylsiloxane) 
Vijaya Sunkara, Dong-Kyu Park, Hyundoo Hwang, Rattikan Chantiwas, Steven A. Soper and Yoon-Kyoung Cho 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00272K, Technical Note 

Stand-alone self-powered integrated microfluidic blood analysis system (SIMBAS) 
Ivan K. Dimov, Lourdes Basabe-Desmonts, Jose L. Garcia-Cordero, Benjamin M. Ross, Antonio J. Ricco and Luke P. Lee 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00403K, Paper 

Hydrogel droplet microarrays with trapped antibody-functionalized beads for multiplexed protein analysis 
Huiyan Li, Rym Feriel Leulmi and David Juncker 
Lab Chip, 2011, 11, 528-534, DOI: 10.1039/C0LC00291G, Paper 

Optoelectrofluidic platforms for chemistry and biology
Hyundoo Hwang and Je-Kyun Park 
Lab Chip, 2011, 11, 33-47, DOI: 10.1039/C0LC00117A, Critical Review 

High-density fabrication of normally closed microfluidic valves by patterned deactivation of oxidized polydimethylsiloxane 
Bobak Mosadegh, Hossein Tavana, Sasha Cai Lesher-Perez and Shuichi Takayama 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00112K, Technical Note

Mechanics of cell spreading within 3D-micropatterned environments 
Marion Ghibaudo, Jean-Marc Di Meglio, Pascal Hersen and Benoit Ladoux 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00221F, Paper

Tackling HIV through robust diagnostics in the developing world: current status and future opportunities 
Darash Desai, Grace Wu and Muhammad H. Zaman 
Lab Chip, 2011, 11, 194-211, DOI: 10.1039/C0LC00340A, Tutorial Review 

Lung assist device technology with physiologic blood flow developed on a tissue engineered scaffold platform 
David M. Hoganson, Howard I. Pryor II, Erik K. Bassett, Ira D. Spool and Joseph P. Vacanti 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00158A, Paper 

Some recent advances in the design and the use of miniaturized droplet-based continuous process: Applications in chemistry and high-pressure microflows 
Nicolas Lorber, Flavie Sarrazin, Pierre Guillot, Pascal Panizza, Annie Colin, Bertrand Pavageau, Cindy Hany, Patrick Maestro, Samuel Marre, Thomas Delclos, Cyril Aymonier, Pascale Subra, Laurent Prat, Christophe Gourdon and Emmanuel Mignard 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00058B, Frontier 

Integrated microfluidic platform for the electrochemical detection of breast cancer markers in patient serum samples 
Alex Fragoso, Daniel Latta, Noemi Laboria, Frithjof von Germar, Thomas E. Hansen-Hagge, Wolfgang Kemmner, Claudia Gärtner, Richard Klemm, Klaus S. Drese and Ciara K. O’Sullivan 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00398K, Paper 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Lab on a Chip? Then why not submit to us today or alternatively email us your suggestions.

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Top ten most accessed articles in November

This month sees the following articles in Lab on a Chip that are in the top ten most accessed:-

Cell lysis and DNA extraction of gram-positive and gram-negative bacteria from whole blood in a disposable microfluidic chip 
Madhumita Mahalanabis, Hussam Al-Muayad, M. Dominika Kulinski, Dave Altman and Catherine M. Klapperich 
Lab Chip, 2009, 9, 2811-2817, DOI: 10.1039/B905065P, Paper 

Overview of single-cell analyses: microdevices and applications 
Sara Lindström and Helene Andersson-Svahn 
Lab Chip, 2010, 10, 3363-3372, DOI: 10.1039/C0LC00150C, Critical Review 

Rails and anchors: guiding and trapping droplet microreactors in two dimensions 
Paul Abbyad, Rémi Dangla, Antigoni Alexandrou and Charles N. Baroud 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00104J, Paper 

Fabrication of monolithic 3D micro-systems 
Pakorn Preechaburana and Daniel Filippini 
Lab Chip, 2011, 11, 288-295, DOI: 10.1039/C0LC00331J, Paper 

Fully integrated lab-on-a-disc for simultaneous analysis of biochemistry and immunoassay from whole blood 
Beom Seok Lee, Yang Ui Lee, Han-Sang Kim, Tae-Hyeong Kim, Jiwoon Park, Jeong-Gun Lee, Jintae Kim, Hanshin Kim, Wee Gyo Lee and Yoon-Kyoung Cho 
Lab Chip, 2011, 11, 70-78, DOI: 10.1039/C0LC00205D, Paper 

Design, engineering and utility of biotic games 
Ingmar H. Riedel-Kruse, Alice M. Chung, Burak Dura, Andrea L. Hamilton and Byung C. Lee 
Lab Chip, 2011, 11, 14-22, DOI: 10.1039/C0LC00399A, Paper 

Cost-effective and compact wide-field fluorescent imaging on a cell-phone 
Hongying Zhu, Oguzhan Yaglidere, Ting-Wei Su, Derek Tseng and Aydogan Ozcan 
Lab Chip, 2011, 11, 315-322, DOI: 10.1039/C0LC00358A, Paper 

A fast and simple method to fabricate circular microchannels in polydimethylsiloxane (PDMS) 
Mohamed Abdelgawad, Chun Wu, Wei-Yin Chien, William R. Geddie, Michael A. S. Jewett and Yu Sun 
Lab Chip, 2011, Advance Article, DOI: 10.1039/C0LC00093K, Technical Note 

Three-dimensional microwell arrays for cell culture 
Christina L. Randall, Yevgeniy V. Kalinin, Mustapha Jamal, Tanmay Manohar and David H. Gracias 
Lab Chip, 2011, 11, 127-131, DOI: 10.1039/C0LC00368A, Communication 

A microfluidic array with cellular valving for single cell co-culture 
Jean-Philippe Frimat, Marco Becker, Ya-Yu Chiang, Ulrich Marggraf, Dirk Janasek, Jan G. Hengstler, Joachim Franzke and Jonathan West 
Lab Chip, 2011, 11, 231-237, DOI: 10.1039/C0LC00172D, Paper 

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Lab on a Chip? Then why not submit to us today or alternatively email us your suggestions.
  

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Microfluidic pinball

A device to deposit polymer layers on oil droplets has been made by researchers from Singapore, who say that their design is faster and

Oil droplets are guided through three liquid streams - two polymers and a washing station - by micropillars arranged in a zigzag fashion

more efficient than conventional deposition techniques and it achieves the highest number of polymer layers reported so far using microfluidics. The device could be used to encapsulate drugs for delivery or be used to create capsules for biosensing.

Dieter Trau from the National University of Singapore and colleagues have used a method that they call ‘microfluidic pinball’ to guide oil droplets through channels created by rows of micropillars, like a pinball machine. The rows are orientated in a zigzag fashion across three liquid streams – two polymers and a washing station. The angles created by the rows, as well as the flow rates in the streams, determine how long droplets stay in each channel.

The droplets are guided along the rows to travel repeatedly through the three streams. The team found that six polyelectrolyte layers could be deposited on a droplet in under three minutes – they were able to see the layers with fluorescence spectroscopy. Atomic force microscopy revealed the thickness of each layer to be approximately 2.8nm.

Read Jennifer Newton’s Chemistry World article online here or go straight to the HOT Lab on a Chip paper:


A microfluidic pinball for on-chip generation of Layer-by-Layer polyelectrolyte microcapsules

Chaitanya Kantak, Sebastian Beyer, Levent Yobas, Tushar Bansal and Dieter Trau,
Lab Chip, 2011
DOI: 10.1039/c0lc00381f

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