Ruthenium catalyst for cancer treatment

Scientists from Germany have designed a new complex which inhibits enzymes and reduces tumour cell growth.

The drug complex consists of N-heterocyclic carbene ligands coordinated to a ruthenium metal centre. Ruthenium N-heterocyclic carbene compounds are largely popular due to their catalytic properties but very little attention has been paid to the biological activity of these species.

Anti-cancer ruthenium N-heterocyclic carbenes

Why not download the article now to find out what the team did…?

Evaluation of arene ruthenium(II) N-heterocyclic carbene complexes as organometallics interacting with thiol and selenol containing biomolecules
Luciano Oehninger, Maria Stefanopoulou, Hamed Alborzinia, Julia Schur, Stephanie Ludewig, Kazuhiko Namikawa, Alvaro Muñoz-Castro, Reinhard W. Köster, Knut Baumann, Stefan Wölfl, William S. Sheldrick and Ingo Ott

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