This Perspective article by Claude Piguet has been selected as a Dalton Transactions Hot article, where the current understanding of the role of energy in self assembly is explained.
Claude Piguet looks at intermolecular interactions in pure materials and diluted solutions, and the thermodynamic considerations behind enthalpy-entropy compensation.
As the author comments, this field is very important as ‘a thorough understanding of the underlying intermolecular connection of an effector to a receptor could be at the origin of some novel design for drugs…’
Professor Piguet is based at the University of Geneva, Switzerland, find out more about his research by visiting his website.
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Enthalpy–entropy correlations as chemical guides to unravel self-assembly processes
Claude Piguet
Dalton Trans., 2011, DOI: 10.1039/C1DT10055F