Single-molecule spectroscopy can provide new insights into the dynamics of biological and material science, but analysing the data from this technique is no simple task. To this end, scientists in Germany have developed a new method for tracking single fluorescent molecules, using linear programming solvers.
Whereas previous methods have involved tracking by hand or with semi-manual systems, this new algorithm means standard computers can be used instead, freeing up the researchers’ time and reducing the risk of mistakes. This new technique is essential for the on-going miniaturization of devices to the nanoscale.
Interested to know more? Read the full article in Chemistry World here…
Read the article from PCCP:
A novel method for automatic single molecule tracking of blinking molecules at low intensities
Dominik Wöll , Christoph Kölbl , Beate Stempfle and Andreas Karrenbauer
Phys. Chem. Chem. Phys., 2013, Advance Article
DOI: 10.1039/C3CP44693J
