Kay Huai-Ying Hsi and colleagues from Massachusetts Institute of Technology detail a strategy for using co-crystallization as a purification method that could be developed for use during the synthesis and manufacturing of pharmaceutical substances and fine chemicals.
This communication will be published as part of a themed issue on crystal engineering and crystallography in the pharmaceutical industry later in the year. It’s currently free so do take a look!
Separation of impurities from solution by selective co-crystal formation
Kay Huai-Ying Hsi, Keith Chadwick, Amanda Fried, Meghan Kenny and Allan S. Myerson
CrystEngComm, 2012
DOI: 10.1039/C1CE06358H