RSC Chemical Biology Blog

We’re excited to share with you our new cross-journal themed collection on “Multimolecular Crowding in Biosystems” for RSC Chemical Biology and ChemComm.

Living cells comprise a variety of molecules from small cations/anions, metabolites, lipids, peptides, to biopolymers such as peptides/proteins, polysaccharides, and nucleic acids. These biomolecules are highly condensed inside the live cells and their distribution and concentration are heterogeneously varied (in a controlled manner). Such multimolecular crowding conditions are sharply distinct from those of conventional biochemical study, should be crucial for elucidating structures and functions of biomolecules in live cells, as well as for developing functional artificial molecules useful in chemical biology study, drug discovery, and medical diagnosis.

In this cross-journal themed issue, explore research papers, reviews, and communications in ChemComm and RSC Chemical Biology concerning chemical, physical, theoretical, or biological characterization of various biomolecules under the multimolecular crowding conditions. Also discover the development of chemical tools and devices enabling the detection and imaging of key biomolecules and the relevant events in live cells, methods for the structural modification and functional switching/control of biomolecules, and analytical or physical chemistry approaches applicable to study of multimolecular crowding biosystems.

Explore some of the papers in the collection below, and see the full collection here: Cross-journal themed collection on ‘Multimolecular Crowding in Biosystems’

Highlight

Fluorescent probes for targeting endoplasmic reticulum: design strategies and their applications
Deepmala Singh, Deeksha Rajput and Sriram Kanvah
Chem. Commun., 2022, 58, 2413-2429
DOI: 10.1039/D1CC06944F

Feature Article

Cancer diagnosis and analysis devices based on multimolecular crowding
Daisuke Onoshima and Yoshinobu Baba
Chem. Commun., 2021, 57, 13655-13661
DOI: 10.1039/D1CC05556A

 Review

Chemogenetics of cell surface receptors: beyond genetic and pharmacological approaches
Yuta Miura, Akinobu Senoo, Tomohiro Doura and Shigeki Kiyonaka
RSC Chem. Biol., 2022, 3, 269-287
DOI: 10.1039/D1CB00195G

Paper

Versatile naphthalimide tetrazines for fluorogenic bioorthogonal labelling
Marcus E. Graziotto, Liam D. Adair, Amandeep Kaur, Pauline Vérité, Sarah R. Ball, Margaret Sunde, Denis Jacquemin and Elizabeth J. New
RSC Chem. Biol., 2021, 2, 1491-1498
DOI: 10.1039/D1CB00128K

We hope you enjoy reading these articles!

Contact us:  chembio-rsc@rsc.org

Visit our website – rsc.li/rsc-chembio

RSC Chemical Biology is an international gold open access journal, publishing exceptionally significant findings in chemical biology.

Sign up now to get updates on all articles as they are published on Twitter and in our e-alerts.

RSC Chemical Biology is delighted to welcome papers for its latest online themed collection on ‘Molecular glues’, guest edited by Professor Michelle Arkin (UCSF, USA), Professor Luc Brunsveld (TU Eindhoven, Netherlands) and Dr Eric Fischer (Dana-Farber Cancer Institute & Harvard Medical School, USA).

Scope

welcome broad studies on molecular glues, including studies on but not limited to protein degradation glues, protein binders and stabilizers. We also welcome studies at the intersection of molecular glues and bi-functional molecules for protein degradation and beyond with a particular interest on molecular recognition.

The deadline for submissions is 30 September 2022.

Submit to the collection now!

Promotion of the collection is scheduled for spring 2023, with articles published online as soon as they’re accepted.

Authors are welcome to submit original research in the form of a Communication or Full Paper.  Articles can be submitted via our website: rsc.li/rsc-chembio. We would be grateful if upon submission you would be able to mention that your manuscript is intended for this themed collection in the “notes to the editor” box.

Please note that before a final decision is made, all submissions are subject to an initial assessment to confirm the manuscript’s suitability for full peer review.

If you have any questions about the journal or the collection, I would be happy to answer them in reply to this email.

With kind regards,

Explore all open calls for papers from RSC journals! 

About RSC Chemical Biology

Led by Hiroaki Suga (University of Tokyo), RSC Chemical Biology is dedicated to publishing and disseminating the most exceptionally significant, breakthrough findings of interest to the chemical biology community. All submissions are handled by our experienced and internationally recognised Associate Editors. For more information on the journal, please visit the journal homepage.

As a gold open access journal, there are no barriers to accessing content and your research article will reach an international audience. Please note that the article processing charges are waived until mid-2022, so the journal is currently free to publish in.

RSC Chemical Biology is now indexed in the Directory of Open Access Journals (DOAJ), PubMed Central, Scopus and Web of Science: Emerging Sources Citation Index.  Find out more about the journal and submit your work at rsc.li/rsc-chembio

RSC Chemical Biology

Royal Society of Chemistry

www.rsc.org

We’re excited to share with you our new topical collection on “Analytical methods in chemical biology” for RSC Chemical Biology, highlighting the excellent work published so far in the journal in this exciting area of research.

This collection seeks to highlight important advancements in fields such as imaging, spectroscopy, sensing and omics.  Analytical methods developed and utilized by chemical biologists encompass a wide range of techniques, including Raman probes for exploring uptake into plant cells, nanobodies for non-invasive imaging, single-cell multi-omics, single-molecule fluorescent sensors and much more.

Explore some of the papers in the collection below, and see the full collection here:

‘Analytical methods in chemical biology’ Topical Collection

Review

Nanobodies as in vivo, non-invasive, imaging agents
Thibault J. Harmand, Ashraful Islam, Novalia Pishesha and Hidde L. Ploegh
RSC Chem. Biol., 2021, 2, 685-701
DOI: 10.1039/D1CB00023C

Communication

Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines
Weifeng Lin, Zhen Yang, Amanpreet Kaur, Annika Block, Miroslav Vujasinovic, J.-Matthias Löhr and Daniel Globisch
RSC Chem. Biol., 2021, 2, 1479-1483
DOI: 10.1039/D0CB00132A

Paper

Versatile naphthalimide tetrazines for fluorogenic bioorthogonal labelling
Marcus E. Graziotto, Liam D. Adair, Amandeep Kaur, Pauline Vérité, Sarah R. Ball, Margaret Sunde, Denis Jacquemin and Elizabeth J. New
RSC Chem. Biol., 2021, 2, 1491-1498
DOI: 10.1039/D1CB00128K

We hope you enjoy reading these articles!

RSC Chemical Biology is an international gold open access journal, publishing exceptionally significant findings in chemical biology.

Sign up now to get updates on all articles as they are published on Twitter and in our e-alerts.

Contact us:  chembio-rsc@rsc.org

Visit our website – rsc.li/rsc-chembio

We’re excited to share with you our new topical collection on “The Chemical Biology of Peptides” for RSC Chemical Biology, highlighting the excellent work published so far in the journal in this exciting area of research.

This collection features work where peptides are used to image immune checkpoints, where they are harnessed to develop novel GPCR ligands, and where they are used to inhibit protein-protein interactions, along with many more fascinating applications and studies.

Explore some of the papers in the collection below, and see the full collection here:  RSC Chemical Biology – The Chemical Biology of Peptides collection

Review

Matters of class: coming of age of class III and IV lanthipeptides
Julian D. Hegemann and Roderich D. Süssmuth
RSC Chem. Biol., 2020, 1, 110-127
DOI: 10.1039/D0CB00073F

Communication

Targeted disruption of PKC from AKAP signaling complexes
Ameya J. Limaye, George N. Bendzunas and Eileen J. Kennedy
RSC Chem. Biol., 2021, 2, 1227-1231
DOI: 10.1039/D1CB00106J

Paper

A peptidic inhibitor for PD-1 palmitoylation targets its expression and functions
Han Yao, Chushu Li, Fang He, Teng Song, Jean-Philippe Brosseau, Huanbin Wang, Haojie Lu, Caiyun Fang, Hubing Shi, Jiang Lan, Jing-Yuan Fang and Jie Xu
RSC Chem. Biol., 2021, 2, 192-205
DOI: 10.1039/D0CB00157K

We hope you enjoy reading these articles!

RSC Chemical Biology is an international gold open access journal, publishing exceptionally significant findings in chemical biology.

Sign up now to get updates on all articles as they are published on Twitter and in our e-alerts.

RSC Chemical Biology is delighted to welcome papers for its latest online themed collection on the ‘Development of bio-orthogonal tools’, guest edited by Professor Chengqi Yi (Peking University, China) and Professor Yan Zhang (Nanjing University, China).

Scope

We would welcome submissions on bio-orthorgonal chemistry, reactions and probes in labeling, manipulating, imaging and sequencing of protein, DNA, RNA and bioactive metabolites.

The deadline for submissions is 30 April 2022.

Promotion of the collection is scheduled for summer 2022, articles will be published online as soon as they’re accepted.

Authors are welcome to submit original research in the form of a Communication or Full Paper.  Articles can be submitted via our website: rsc.li/rsc-chembio. We would be grateful if upon submission you would be able to mention that your manuscript is intended for this themed collection in the “notes to the editor” box.

Please note that before a final decision is made, all submissions are subject to an initial assessment to confirm the manuscript’s suitability for full peer review.

 If you have any questions about the journal or the collection, please contact the editorial office via chembio-rsc@rsc.org.

With kind regards,

About RSC Chemical Biology

Led by Hiroaki Suga (University of Tokyo), RSC Chemical Biology is dedicated to publishing and disseminating the most exceptionally significant, breakthrough findings of interest to the chemical biology community. All submissions are handled by our experienced and internationally recognised Associate Editors. For more information on the journal, please visit the journal homepage.

As a gold open access journal, there are no barriers to accessing content and your research article will reach an international audience. Please note that the article processing charges are waived until mid-2022, so the journal is currently free to publish in.

RSC Chemical Biology is now indexed in the Directory of Open Access Journals (DOAJ), PubMed Central, Scopus and Web of Science: Emerging Sources Citation Index.  Find out more about the journal and submit your work at rsc.li/rsc-chembio

RSC Chemical Biology

Royal Society of Chemistry

www.rsc.org