New themed collection on ‘Biomolecular Technologies’

We’re pleased to inform you that this new themed collection from RSC Chemical Biology has now been published online.

Read the collection here

 

As both chemical and biological engineering approaches continue to expand, the landscape of biomolecular technologies is rapidly evolving, affording new opportunities from basic science to real-world applications. Guest Edited by Prof. Sheel Dodani (The University of Texas at Dallas; ORCID 0000-0003-0271-6080) and Prof. Ariel Furst (Massachusetts Institute of Technology; ORCID 0000-0001-9583-9703), this themed collection brings together engineered biomolecule-based technologies spanning small molecules, nucleic acids, and proteins, with applications in biocatalysis, biosensing, and synthetic biology. Each study showcases the modular and tunable nature of biomolecular design to tailor properties for function in both aqueous solutions and biological environments.

 

The articles in this collection are featured below. All articles in RSC Chemical Biology are open access and free to read.

Editorial

Introduction to “Biomolecular Technologies”

Sheel C. Dodani and Ariel Furst

RSC Chem. Biol., 2025, DOI: 10.1039/D5CB90031J

Communication

A chemigenetic indicator based on a synthetic chelator and a green fluorescent protein for imaging of intracellular sodium ions

Shiori Takeuchi, Shosei Imai, Takuya Terai and Robert E. Campbell

RSC Chem. Biol., 2025, 6, 170–174 DOI: 10.1039/D4CB00256C

Papers

An expanded substrate scope for cross-chiral ligation enables efficient synthesis of long L-RNAs

Xuan Han and Jonathan T. Sczepanski

RSC Chem. Biol., 2025, 6, 209–217 DOI: 10.1039/D4CB00253A

 

Functionalization of a versatile fluorescent sensor for detecting protease activity and temporally gated opioid sensing

Jennifer Sescil, Hailey Fiel, Steven M. Havens, Emma Fu, Xingyu Li, Kayla E. Kroning, Isabel Solowiej, Peng Li and Wenjing Wang

RSC Chem. Biol., 2025, 6, 555–562 DOI: 10.1039/D4CB00276H

 

Regulating ferredoxin electron transfer using nanobody and antigen interactions

Albert Truong and Jonathan J. Silberg

RSC Chem. Biol., 2025, 6, 746–753 DOI: 10.1039/D4CB00257A

 

Real-time bioluminescence imaging of nitroreductase in breast cancer bone metastasis

Kang Lu, Mengxi Zhang, Zuotong Tian and Han Xiao

RSC Chem. Biol., 2025, 6, 754–760 DOI: 10.1039/D4CB00310A

 

We hope you enjoy this new themed collection from RSC Chemical Biology.