A focus on drug safety and efficacy

Assessing and preventing adverse effects of pharmaceutical products is an important part of medicinal chemistry and drug development. The RSC Drug Discovery and Issues in Toxicology Series includes a broad range of books on drug efficacy and drug safety, or pharmacovigilance.

Take a look at the books below to find out more about issues involved in safety and efficacy of drugs and techniques for their evaluation. All these books are available as eBooks and you can access the front matter, table of contents and the first chapter of all these for free. Why not recommend them to your library?

These titles are a great resource for scientists involved in drug discovery and development and drug metabolism studies. They are also a valuable guide for regulators concerned with the safety evaluation of chemicals and postgraduate medicinal chemists.

Recently published:

Chemical Toxicity Prediction: Category Formation and Read-Across
Mark Cronin, Judith Madden, Steven Enoch and David Roberts (978-1-84973-384-7, Issues in Toxicology)

Comprehensive Biomarker Discovery and Validation for Clinical Application
Péter Horvatovich and Rainer Bischoff (978-1-84973-422-6, RSC Drug Discvovery)

More key texts:

Designing Multi-Target Drugs
J. Richard Morphy and C John Harris (978-1-84973-362-5, RSC Drug Discovery)

New Horizons in Predictive Toxicology: Current Status and Application
Alan G E Wilson (978-1-84973-051-8, RSC Drug Discovery)

Also highly recommended:

Cytochromes P450: Role in the Metabolism and Toxicity of Drugs and other Xenobiotics
Costas Ioannides (978-0-85404-274-6, Issues in Toxicology)

Nanostructured Biomaterials for Overcoming Biological Barriers
Maria Jose Alonso and Noemi S. Csaba (978-1-84973-363-2, RSC Drug Discovery)

Biomedical Imaging: The Chemistry of Labels, Probes and Contrast Agents
Martin Braddock (978-1-84973-014-3, RSC Drug Discovery)

Metabolism, Pharmacokinetics and Toxicity of Functional Groups: Impact of Chemical Building Blocks on ADMET
Dennis A Smith (978-1-84973-016-7, RSC Drug Discovery)

Coming soon:

Metabolic Profiling: Disease and Xenobiotics
Martin Grootveld (9781849731638, Issues in Toxicology)
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Happy Birthday to Paul O’Brien!

Happy birthday to Paul O’Brien FRS, University of Manchester, from the RSC Books Team!

The Editor-in-Chief for the RSC Nanoscience & Nanotechnology Series celebrates his 60th Birthday this month.

Paul has been involved with the highly successful Series since 2008, which has seen the publication of key titles on Nanotubes & Nanowires and Fullerenes. New forthcoming titles include Nanodiamond and Semiconductor Quantum Dots.

Paul is also Editor of the new Nanoscience Specialist Periodical Reports.

We wish him many happy returns on his 60th Birthday!

PS. Don’t forget to read the themed Journal articles in celebration of Paul O’Brien’s 60th birthday as well!

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New Books Published in Polymer Chemistry

Read the latest titles in the RSC Polymer Chemistry Series:

Conjugated PolymersConjugated Polymers: A Practical Guide to Synthesis edited by Klaus Müllen, Max Planck Institute for Polymer Research, Germany; John R Reynolds, Georgia Institute of
Technology, USA and Toshio Masuda, Fukui University of Technology, Japan

Edited by world leading experts in the field of conjugated polymer synthesis, the book serves as a convenient guide for advanced undergraduate level and above.

Polymeric Materials with Antimicrobial Activity: From Synthesis to Applications edited by Alexandra Muñoz-Bonilla, María Cerrada and Marta Fernández-García, Institute of Science and
Technology of Polymers, Spain

A comprehensive overview of different antimicrobial polymeric materials, their antimicrobial action modes and applications.

Natural Rubber Materials Volume 1: Blends and IPNs
Natural Rubber Materials Volume 2: Composites and Nanocomposites
Edited by Hannah J Maria, Rajisha K R, Jithin Joy and Sabu Thomas, Mahatma Ghandi University, India;  Chin Han Chan, MARA University of Technology, Malaysia and Laly A Pothen, Bishop Moore College, India

This comprehensive two volume set covers the synthesis, characterization and applications of natural rubber based blends, interpenetrating polymer networks, composites and nanocomposites.

Dont’t forget, everyone can access the table of contents, preface and first chapter of the eBooks above for free by registering for an RSC Publishing Personal Account.

Look out for the forthcoming title in the Series:

Phosphorus-Based Polymers: From Synthesis to Applications edited by Sophie Monge, University of Montpellier 2, France and Ghislain David, Institute Charles Gerhardt of Montpellier, France

New Textbook Published:

Polymer Structure Characterization: From Nano to Macro Organization in Small Molecules and Polymers, 2nd Edition
Richard A Pethrick, University of Strathclyde, UK

A textbook aimed at polymer and material scientists, but also of interest to chemists and physicists studying organic materials.

For further information on our course materials and to request an inspection copy click here.

Interested in writing a book? Contact the Materials Books Commissioning Editor, Leanne Marle for more information about publishing books with the Royal Society of Chemistry.

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Updates from the Issues in Toxicology and RSC Drug Discovery Series

Check out these recently published new titles in the Issues in Toxicology Series

The Carcinogenicity of Metals
Human risk through occupational and environmental exposure
Authored by Alan B. G. Lansdown

Chemical Toxicity Prediction
Category Formation and Read-Across
Authored by Mark Cronin, Judith Madden , Steven Enoch and David Roberts

Advances in Dermatological Sciences
Edited by Robert Chilcott and Keith R. Brain

Reducing, Refining and Replacing the Use of Animals in Toxicity Testing
Edited by Dave Allen and Mike D Waters

…And these recently published books in the RSC Drug Discovery Series

Pain Therapeutics
Current and Future Treatment Paradigms
Edited by Charlotte Allerton

Inhibitors of Molecular Chaperones as Therapeutic Agents
Edited by Timothy D Machajewski and Zhenhai Gao

The first chapter and table of contents for all of the above are free to view.
To access any of our free content you need to register for a free personal RSC Publishing account, and then login using your details. You will find our registration page here ….


To briefly introduce myself, my name is Rowan Frame and I am delighted to have recently joined the Royal Society of Chemistry Books Team. I will be covering the role of Cara Sutton, the current Commissioning Editor for books in the Issues in Toxicology, RSC Drug Discovery and RSC Metallobiology Series, who will be taking maternity leave in 2014.

If you are interested in writing a book in one of these areas, please get in touch. I look forward to hearing from you!


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New RSC Soft Matter Series launched

Soft matter is a fast developing area of research. To map these exciting changes, the first title in the new RSC Soft Matter Series was published this November. Functional Molecular Gels, edited by Beatriu Escuder and Juan Miravet, Universitat Jaume I in France, covers recent rapid developments in molecular gels, and highlights important discoveries from the exponentially growing body of literature in this field.

Functional Molecular Gels covers the design and characterisation of molecular gels, gels responsive to physical, chemical, and biological stimuli, and the biomedical, optic, electronic, and nanostructural applications of these gels.

The next title in the RSC Soft Matter Series will be published in 2014: Hydrogels in Cell-Based Therapies, edited by Che J. Connon and Series Editor Ian W. Hamley, University of Reading.

Working alongside Ian Hamley as Series Editors are Hans-Jürgen Butt, Max Planck Institute for Polymer Research, Germany; Howard Stone, Princeton University, US; and Chi Wu, The Chinese University of Hong Kong. All are prominent and active researchers in soft matter research, and bring a wealth of knowledge and experience to the Series Editorial Board.

This new Series makes an exciting complement to the Royal Society of Chemistry’s work in this area, which already includes the successful journal Soft Matter.

More titles of interest in this area include Smart Materials for Drug Delivery edited by Carmen Alvarez-Lorenzo and Angel Concheiro, Janus Particle Synthesis, Self-Assembly and Applications  edited by Shan Jiang and Steve Granick, and Polymeric and Self Assembled Hydrogels edited by Xian Jun Loh and Oren A. Scherman.

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An Easier Way to Keep up With the Literature

Keeping up with the literature can be time consuming, if not a little daunting; the daily influx of email alerts and RSS feeds can feel like drinking from a fire hydrant, Sometimes it is helpful to view the literature from a different viewpoint; a full appreciation of recent developments and breakthroughs can only be gained when examining the literature as the bigger picture.

As a solution to this, the Royal Society of Chemistry has been publishing Specialist Periodical Reports for more than four decades. Published annually online and in print, each volume is dedicated to a particular scientific discipline, and comprises of critical and comprehensive reviews of the recent literature.

The series is overseen by an editorial board of renowned experts in the field. Chapter authors are hand-picked by the editors, guaranteeing informed and respected opinion throughout. Coverage of the literature is excellent, each chapter typically cites between 150-300 papers, providing the reader with a comprehensive view of the latest progress in their field.

In addition to several long-standing volumes in the series, the Royal Society of Chemistry is pleased to announce the following new titles:

Electrochemistry

First published in the 1980’s, Electrochemistry returned in 2012 with new volume editors Professor Richard Compton (University of Oxford, UK) and Professor Jay Wadhawan (University of Hull, UK). The latest volume covers a broad range of topics, all with an emphasis on the nano aspects of electrochemistry.

Nanoscience

Launched in 2012, and with volume two publishing in December 2013, Nanoscience ensures readers will be well-versed in the latest research and methodologies. Some of the invited chapters present a special focus in emerging countries working in the field, such as India and China. The volume is overseen by editors Professor Paul O’Brien FRS (University of Manchester, UK) and Professor P John Thomas (University of Bangor, UK).

Synthetic Biology

Launching in early 2014, this new SPR will present a digest of the cutting-edge of this emerging field. As with any multi-disciplinary field, there is an immense and rapidly-growing body of literature concerning synthetic biology, with several dedicated journals now available. The series editors, Max Ryadnov (National Physical Laboratory, UK), Luc Brunsveld (Eindhoven University of Technology, The Netherlands), and Hiroaki Suga (University of Tokyo, Japan) are active in the field, ensuring that the most valuable information is presented in an authoritative manner.

Read Online!

SPRs are included in the RSC eBook collection, and are indexed in Scopus and the Thomson Reuters Books Citation Index. Purchasers of the print edition are entitled to free online institutional access via the registration card included in each volume. Both the first chapter of each volume and the table of contents are always free to view.

Read Nanoscience and Electrochemistry today!

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2014 Books Catalogue

Books Catalogue 2014Be the first to see our stunning new collection of authoritative titles detailing the latest advances and highlighting technology, opinions and perspectives in modern science.

Presented in a combination of monographs, professional references, textbooks and popular science titles, the 2014 collection embraces diverse subjects including biological sciences, analytical chemistry and environmental chemistry, food science and nutrition.

Our 2014 highlights include:

You’ll find our books appeal to a wide readership including scientists – from academia to industry – and everyone who teaches, studies or enjoys chemistry.

So browse the NEW Books Catalogue 2014 – your guide to the best and most diverse choice of chemical sciences titles out there.

*The name THE MERCK INDEX is owned by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Whitehouse Station, N.J., U.S.A., and is licensed to The Royal Society of Chemistry for use in the U.S.A. and Canada.

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Medicinal chemistry developments

Emerging drugs and targets for Parkinsons disease

Emerging drugs and targets for Parkinsons disease

Now is an important time for medicinal chemistry. This week Professor Giovanna Mallucci’s team at the University of Leicester reported landmark findings for developing future treatments of neurodegenerative diseases, such as Alzheimer’s, Huntingdon’s and Parkinson’s. Research into these diseases is a crucial part of coping with aging populations. The Royal Society of Chemistry’s timely publication Emerging Drugs and Targets for Parkinson’s Disease edited by Ana Martinez and Carmen Gil, reviews state of the art treatments for Parkinson’s Disease and assesses promising future treatments.

Another Royal Society of Chemistry title published this summer is Supramolecular Systems in Biomedical Fields edited by Hans-Jörg Schneider. Supramolecular chemistry is an increasingly important field for drug delivery systems, as shown by Ran Lin and coworkers in a ChemComm article in April this year.

More new, topical titles recently published include Biotherapeutics edited by Lyn H Jones and Andrew J McKnight,  New Applications of NMR in Drug Discovery and Development edited by Leoncio Garrido and Nicolau Beckmann, and Chromatographic Methods in Metabolomics edited by Tuulia Hyotylainen and Susanne Wiedmer.

If you have an idea for a book or you would like to find out more about the RSC Drug Discovery, Issues in Toxicology or RSC Metallobiology Series please contact the medicinal chemistry Commissioning Editor, Cara Sutton.

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RSC Book author wins Nobel Prize

RSC Books would like to congratulate Martin Karplus, Michael Levitt and Arieh Warshel, who have today been jointly awarded the Nobel Prize for Chemistry.   The researchers have been awarded the prestigious prize for their work in the development of multiscale computational models for complex chemical systems.

Ariel Warshel has twice written on this subject for RSC books, read more in Quantum Tunnelling in Enzyme-Catalysed Reactions and Computational and Structural Approaches to Drug Discovery.

Want to know more about computational chemistry?  Find out more in the RSC Drug Discovery and RSC Biomolecular Sciences Book series.

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One day workshop: Developing analytical tools for the life sciences

Analytical tools for life sciences

Analytical tools for life sciences workshop

The Royal Society of Chemistry and the Biochemical Society are holding a one day workshop on “Tools and Strategies to Find Chemical Probes for Your Protein – The Role of Computer-Aided Drug Discovery.” The event will be at Charles Darwin House, London, on 15th November 2013.

Aimed at developing analytical tools for the life sciences, this event will be of interest to biologists facing challenges in finding new chemical reagents for understanding biological mechanisms, as well as computational biologists and chemists. The workshop will include discussions on molecular docking for probe discovery, virtual screening, and generating chemical probes, amongst other topics. This will be a fruitful opportunity for those interested in developing interdisciplinary collaborations in this exciting field.

The Royal Society of Chemistry publishes a range of titles in this area, which would provide an excellent accompaniment to this meeting.  Titles such as Physico-chemical and computational approaches to drug discovery (2012) provide a grounding in the computational aspects, while the more recently published Computational approaches to nuclear receptors (2013) will interest those more specifically interested in applying these principles to the nucleus. Highly relevant to those with pharmaceutical and biomedical interests, Drug design strategies (2012) and Biotherapeutics (2013) give in depth coverage of state of the art developments in these fast changing fields.

The deadline for abstract submissions is 16th September 2013. Flash poster presentation slots are currently still available.

Registration is free to members of the Royal Society of Chemistry and the Biochemical Society. Find further details and register here.

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