Author Archive

RSC Book author wins Nobel Prize

RSC Books would like to congratulate Robert J. Lefkowitz and Brian K. Kobilka who have today been jointly awarded the Nobel Prize in Chemistry.  The researchers have been awarded the prize for their studies of G-protein-coupled receptors.

If you would like to learn more about this fast developing area why not read Robert J Lefkowitz’s engaging historical perspective on G-protein-coupled receptors published in the RSC Drug Discovery book G Protein-Coupled Receptors: From Structure to Function.

Learn more here.

Interested in other books on drug discovery?  Read more in the RSC Drug Discovery Series.

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Understanding Drug Degradation

A good understanding of the organic chemistry of drug degradation is essential when considering the stability, efficacy and safety of a drug product.  A poor understanding of these mechanisms could result in an ineffective drug and could affect the shelf life of the product.

Organic Chemistry of Drug Degradation authored by Min Li is the latest book to be published in the RSC Drug Discovery Series.  Written by an expert in the field with firsthand experience of drug design and development, the book discusses degradation pathways and mechanisms, regulatory requirements and guidelines.

Complemented by drug degradation case studies, this book will provide an invaluable resource for medicinal chemists, pharmaceutical and analytical scientists working in both academia and industry.

Learn more about degradation here.

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Shedding light on photosynthesis reactions

It has been 100 years, almost to the day, since Italian Chemist Giacomo Luigi Ciamician first proposed harnessing the sun’s power to produce energy.  Writing in Science, Ciamician stated “And if in a distant future the supply of coal becomes completely exhausted, civilization will not be checked by that, for life and civilization will continue as long as the sun shines!”.  With these words in mind, we have selected Proton-Coupled Electron Transfer: A Carrefour of Chemical Reactivity edited by Sebastiao Formosinho and Monica Barroso as the October book of the month. 

Amongst other topics, this fascinating book discusses both natural and artificial photosynthesis and highlights the importance of proton-coupled electron transfer in biological systems, in particularly for bioenergetic conversion. 

The book gives a good insight into current research on a vibrant topic. It is to be expected that it will be the first in a long upcoming list of publications, given the importance of PCET processes such as the activation of water, production of H2, reduction of CO2, and reduction of N2.”  Reviewed in Angewandte Chemie International Edition.

Using personal accounts of experimental examples this book will provide a unique insight into the current understanding of this important reaction type.

Let the sun shine on your reactions.

Interested in other books on catalysis? Read more in the RSC Catalysis Series.

You may also be interested in the latest themed issue of Energy & Environmental Science on ‘Proton-coupled electron transfer’ .

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Want your project to stand out from the crowd? Let us offer the formula for success

The most recently published student guide from RSC books is Research Project Success: The Essential Guide for Science and Engineering Students. Aimed at all students about to begin a project, whether undergraduate or postgraduate, this book introduces the core components common to the majority of projects within physical, engineering or life sciences and provides guidance and tips on how to overcome difficulties and achieve project success.

From initial steps in choosing, researching and beginning a project, through to constructing a dissertation and producing posters and oral presentations, this guide will assist students from start to finish, allowing them to dip in and out when necessary, particularly in those daunting “how to?” and “what if?” moments.

Using case studies and examples to highlight the relevance of the processes outlined, and written in an engaging and often humorous manner, Research Project Success will provide an essential straight-to-the-point reference guide for any project student.

Use the right formula for a winning project.

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Stepping up to the challenge of Type 2 Diabetes

The incidence of Type 2 diabetes is increasing globally at a dramatic rate.  Sufferers are twice as likely to develop cardiovascular disease or have a stroke, and the long term health complications can be serious and debilitating. 

The cost of managing and treating this disease and its many complications are staggering and many of the currently approved therapies are inadequate, resulting in unmet needs and insufficient treatment.

Providing an overview of the most recent advances in small molecule discovery, New Therapeutic Strategies for Type 2 Diabetes, edited by Robert M Jones and published in the RSC Drug Discovery series, will enable readers to understand the trials and tribulations of developing new oral medications aimed at the treatment of this global epidemic.

Each chapter is written by a recognised expert and explains the biological mechanism underpinning each of the medicinal chemistry strategies highlighted.  New Therapeutic Strategies for Type 2 Diabetes will provide both biologists and medicinal chemists with a key text on this important medicinal and economic issue.

Find out how chemists are tackling this global killer here.

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How do you find out the structure of a protein?

The last decade has resulted in many exciting developments in NMR spectroscopy techniques and methods. NMR spectroscopy is a highly versatile and widely used method in biomolecular science, particularly for the structural elucidation of nucleic acids, proteins and carbohydrates. 

The most recent title in the RSC Biomolecular Sciences series, Recent Developments in Biomolecular NMR edited by Marius Clore and Jennifer Potts, will cover these important and exciting developments in NMR, with a particular influence on their impact on biomolecular science. 

Covering all the major advances, and edited by leading spectroscopists, the book will form an essential text for researchers in both industry and academia.

Learn more about the impact of NMR here.

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Discovering drugs comes naturally

Pharmaceutical scientists have long been inspired by natural products in their quest for novel therapeutic agents, and many effective treatments are sourced from natural products.  The most recently published title in the Drug Discovery Series, Drug Discovery from Natural Products edited by Olga Genilloud and Francisca Vicente, reviews the recent trends in this area and describes some of the leading candidates being used as a starting point in novel drug development. 

The book begins by describing the recent approaches to exploiting the potential of microbial resources and goes on to explain the biosynthetic tools that have led to drug discovery from natural products. The detailed descriptions of the multiple stages of modern drug development are complemented by case studies presented by leading experts from academia and industry to give a unique commentary on the current state-of-the-art knowledge in natural product chemistry.

Benefitting from the editors and authors extensive experience in natural product drug discovery, microbiologists, medicinal chemists, pharmacologists and researchers based in academia and industry will find this an invaluable tool to understanding the impact of natural products on drug discovery techniques.

Learn more about natural products here.

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Spilling the beans…

Beans, lentils and peas are recognised as pulses and, like cereals, are widely acknowledged as a globally important food due to their dietary and economic significance. Cultivated throughout the world the processing of this food stuff is amongst the most oldest and most important in food science.

Pulse Chemistry and Technology, written by Brijesh Tiwari and Narpinder Singh, is the first book dedicated solely to the area of pulse processing and chemistry. Serving as a comprehensive guide, the book describes the importance of pulses, the trends in consumption and production and details the physical and chemical characteristics of their constituents and how these can be effectively utilised.

Providing an up-to-date insight into pulse science, processing and technology, the book will serve as an invaluable comprehensive guide for undergraduate and postgraduate students, academic and industry experts working in all areas of grain processing.

Enjoy the revelations here.

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Nanostructured biomaterials: tiny, but overcoming huge hurdles!

Overcoming biological barriers is one of the most important challenges when developing nanomaterials to deliver drugs, vaccines, genes and cellular therapies.  The most recent title published in the popular Drug Discovery Series tackles this issue, providing detailed and comprehensive discussion of the advances being made in this medically and commercially important area.

Nanostructure Biomaterials for Overcoming Biological Barriers edited by Maria Jose Alonso and Noemi S Csaba will be an essential text for pharmaceutical chemists working in industry and academia, but will also be highly relevant to any scientist working within drug development or therapeutic delivery research.

Find out how to overcome biological barriers here.

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How do you develop an anti-inflammatory drug?

Anti-inflammatory drug discovery is an important and rapidly expanding area of therapeutic research, the development of orally-active medicines is crucial to maintaining the quality of life of those suffering from a variety of conditions such as rheumatoid arthritis, asthma, psoriasis and inflammatory bowel disease.  

Anti-inflammatory Drug Discovery edited by Jeremy Levin and Stefan Laufer is the latest title to be published in the Drug Discovery book series and highlights the recent efforts, successes and failures in the development of  targeted therapeutics. Written by respected experts working in the field, this title provides detailed explanations of the biological pathways, targets and medicinal chemistry strategies involved in drug development and will serve as a valuable resource for any researchers or scientists interested in the discovery of anti-inflammatory drugs.

Discover more about anti-inflammatory drugs here.

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