Rowan Frame, Commissioning Editor – Page 2

Author Archive

RSC books to support your antimicrobial research

10 Jul 2014

On average antibiotics add 20 years to each person’s life, yet the rise of antimicrobial resistance is threatening to make them ineffective in the future.

Last month, the public voted for antibiotic resistance to be the challenge of the 2014 Longitude Prize. This month, David Cameron announced a review into why so few anti-microbial drugs have been introduced in recent years.

Are you are a researcher working in the antimicrobial area? Do you want to learn more about the important challenge of antimicrobial resistance? Are you planning to submit an entry to the Longitude Prize? We have a range of books of interest to you. Click on the titles below to find out more about these books:

Successful Strategies for the Discovery of Antiviral Drugs
Manoj C. Desai (Editor), Nicholas A. Meanwell (Editor)
ISBN (print): 978-1-84973-657-2, Copyright: 2013

Polymeric Materials with Antimicrobial Activity: From Synthesis to Applications
Alexandra Muñoz-Bonilla (Editor), María Cerrada (Editor), Marta Fernández-García (Editor)
ISBN (print): 978-1-84973-807-1, Copyright: 2013

Biointerfaces: Where Material Meets Biology
Dietmar Hutmacher (Editor), Wojciech Chrzanowski (Editor)
ISBN (print): 978-1-84973-876-7, Copyright: 2014

Silver in Healthcare: Its Antimicrobial Efficacy and Safety in Use
Alan B. G. Lansdown (Author)
ISBN (print): 978-1-84973-006-8, Copyright: 2010

Photodynamic Inactivation of Microbial Pathogens: Medical and Environmental Applications
Michael R Hamblin (Editor), Giulio Jori (Editor)
ISBN (print): 978-1-84973-144-7, Copyright: 2011

Life Saving Drugs: The Elusive Magic Bullet
John Mann (Author)
ISBN (print): 978-0-85404-634-8, Copyright: 2004

Life Saving Drugs

Biointerfaces Polymeric Materials with Antimicrobial Activity

Silver in Healthcare Successful Strategies for the Discovery of Antiviral Drugs

Photodynamic Inactivation of Microbial Pathogens

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Histological Techniques: An Introduction for Beginners in Toxicology

16 Jun 2014

Do you want to learn more about histological techniques and how to apply them successfully for you work? Histological Techniques by Robert Maynard, Noel Downes and Brenda Finney is the book for you! You can find out more on our website and buy the book here.

Histological techniques form the basis of many areas of research, yet they can often be poorly understood. Aimed at postgraduate students and those at an early stage of their career, this title provides a detailed and comprehensive introduction to histological techniques.

In this book you will find a unique overview of the area with a guide to how to use and incorporate histological techniques within your own research, illustrated with detailed images and slides throughout. Chapters cover:

• An Introduction to Histopathology

• The Light Microscope

• How to Examine Histological Sections

• Tissue Processing: Fixation, Dehydration and Clearing

• Paraffin Wax: Embedding and Section Cutting

• Standard Staining Techniques

• The Theoretical Basis of Histological Staining

• Histochemistry

You may also be interested in books in the Issues in Toxicology Series. This Series is devoted to coverage of modern toxicology and assessment of risk. Written by expert scientists from academia, government and industry, each book serves as a reference and guide to investigations in toxicology, biomedicine, biochemistry, forensics and environmental/pollution sciences. Find out more here or email Rowan Frame at framer@rsc.org

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Book Series Editor-in-Chief is Entrepreneur of the Year

03 Jun 2014

The RSC Chemical Biology Book Series is a new venture that aims to provide a suite of high level research books on cutting-edge research at the interface of chemistry and biology. We are delighted to have recently appointed Professor Tom Brown as Editor-in-Chief.

Tom has been announced as the Chemistry World Entrepreneur of the Year. He is responsible for three tremendously successful start-ups, Oswel, ATDBio and Primer Design. Read his entrepreneurial story in the recent article in Chemistry World, Triple-Stranded Success Story, by Sarah Houlton.

Tom received his first degree and PhD in Chemistry at Bradford University. He moved to Nottingham University, then to Oxford and Cambridge University to carry out postdoctoral research. In 1985 he was appointed to a lectureship in Biological Chemistry at Edinburgh University where he was promoted to Reader then Professor of Nucleic Acids Chemistry. He moved to a Chair in Chemical Biology at Southampton University in 1995. As well as his continuing involvement in ATDBio and Primer Design, Tom is now an academic at the University of Oxford. His research interests lie in nucleic acid chemistry, DNA sequence recognition and the application of nucleic acids to nanotechnology, diagnostics and biology.

Tom co-edited the book, DNA Conjugates and Sensors, with Professor Keith Fox, University of Southampton. Find out more about this excellent volume, which describes the preparation of DNA-conjugates and their applications as aptamers, riboswitches and nanostructures here…

DNA Conjugates and Sensors, Keith R Fox (Editor), Tom Brown (Editor), ISBN: 978-1-84973-427-1, Copyright 2012

You might also be interested to read some of Tom’s recent articles:

Triplex-mediated analysis of cytosine methylation at CpA sites in DNA
Marie W. Johannsen, Simon R. Gerrard, Tracy Melvin and Tom Brown
Chem. Commun., 2014,50, 551-553, DOI: 10.1039/C3CC45917A, Communication

Self-reporting hybridisation assay for miRNA analysis
Jo-Anne Riley, Tom Brown, Nittaya Gale, Julie Herniman and G. John Langley
Analyst, 2014,139, 1088-1092, DOI: 10.1039/C3AN01825C, Paper

Combined nucleobase and backbone modifications enhance DNA duplex stability and preserve biocompatibility
Afaf H. El-Sagheer and Tom Brown
Chem. Sci., 2014,5, 253-259, DOI: 10.1039/C3SC51753E, Edge Article

Gold nanoparticles and fluorescently-labelled DNA as a platform for biological sensing
Amelie Heuer-Jungemann, Pascal K. Harimech, Tom Brown and Antonios G. Kanaras
Nanoscale, 2013,5, 9503-9510, DOI: 10.1039/C3NR03707J, Minireview

If you would like more information about the new RSC Chemical Biology Series, would like to be involved in a book project in this area, or would like to suggest ideas for book topics, please get in touch with Rowan Frame, Books Commissioning Editor at framer@rsc.org.

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Books Can Be Therapeutic…

01 May 2014

Take a look at these latest “therapeutic” titles in the RSC Drug Discovery Series:

Biotherapeutics: Recent Developments using Chemical and Molecular Biology
Edited by Lyn H Jones and Andrew J McKnight
ISBN: 978-1-84973-601-5

Inhibitors of Molecular Chaperones as Therapeutic Agents
Edited by Timothy D Machajewski and Zhenhai Gao
ISBN: 978-1-84973-666-4

Pain Therapeutics
Edited by Charlotte Allerton
ISBN: 978-1-84973-645-9

“This book is a well-balanced reference manual for new entrants into pain drug discovery or a general resource for the overview of the current state of pain therapeutics for more experienced researchers” Source: ChemMedChem 2014, 9, 855 – 857

Also, look out for these books coming out next in the series:

Interested in writing a book? Contact the Medicinal Chemistry Commissioning Editor, Rowan Frame, for more information about publishing books with the Royal Society of Chemistry.

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Parkinson’s Disease

11 Apr 2014

Affecting over 1.5 million people across the world, Parkinson’s disease is a progressive neurological condition. It affects 1.5% of the global population over 65 years of age. As life expectancy is increasing, over the next few years the number of patients with Parkinson´s disease will grow exponentially. To date, there are no available treatments that are capable of curing Parkinson´s disease, and the current goal of therapy, dopamine replacement strategies, is to reduce symptoms.

Today is World Parkinson’s Disease Day – a day for raising awareness and for educating the community of its causes, symptoms and the medical/surgical treatment methods available. The first World Parkinson’s Disease Day, which commemorated the birthday of Dr James Parkinson, also saw the launch of the EPDA’s Charter for People with Parkinson’s. More than 30 Parkinson’s organisations around the world united on the same day to support the Charter.

To support the work of researchers in industry and academia involved in drug discovery for Parkinson’s Disease, the Royal Society of Chemistry recently published Emerging Drugs and Targets for Parkinson’s Disease, edited by Ana Martinez and Carmen Gil.

“Altogether, I can recommend this volume of the excellent RSC Drug Discovery Series to medicinal chemists, (chemical) biologists and pharmacologists interested in drug development for Parkinson’s Disease” Prof. Christa E. Muller, ChemMedChem

Find out more about the RSC Drug Discovery Series at http://rsc.li/drug-discoveryor email framer@rsc.org

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Hanafy Ismail wins best poster at RSC BMCS Meeting

06 Mar 2014

RSC_BMCS_Metabolism, Pharmacokinetics and Toxcity of Functional Groups

The prizewinner, Hanafy Ismail, with Dr Andrew Stachulsk of the Organising Committee

The recent Royal Society of Chemistry Biological & Medicinal Chemistry Sector Meeting on new perspectives in DMPK was held at The Chemistry Centre, Burlington House, in London.

Hanafy Ismail, University of Liverpool, was awarded the prize for the best flash presentation and poster, which was entitled ‘Probing Molecular Targets of the Endoperoxides: A Proteomic Approach’.

Hanafy was awarded with a book from the RSC Drug Discovery Series, Metabolism, Pharmacokinetics and Toxicity of Functional Groups: Impact of Chemical Building Blocks on ADMET, Edited by Dennis A Smith.

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RSC Books at the SOT Annual Meeting & ToxExpo

03 Mar 2014

The RSC are exhibiting at this year’s SOT Annual Meeting and ToxExpo in Pheonix later this month, and there will be a range of books and journals on display at our stand. I will be at Exhibition Booth #1540 during the ToxExpo with Marie Cote, Deputy Editor of Toxicology Research.

Email me if you are attending and would like to arrange a meeting. I would be delighted to meet you!

Here’s just a few of the titles that will be on display from our Issues in Toxicology and RSC Drug Discovery Book Series:

Environmental Cardiology: Pollution and Heart Disease

Aruni Bhatnagar (Editor)
ISBN: 978-1-84973-005-1

Chemical Toxicity Prediction: Category Formation and Read-Across

Mark Cronin (Author), Judith Madden (Author), Steven Enoch (Author), David Roberts (Author)
ISBN: 978-1-84973-384-7

New Horizons in Predictive Toxicology: Current Status and Application

Alan G E Wilson (Editor)
ISBN: 978-1-84973-051-8

You can find all of our recently published books on our website, and you can access the front matter, table of contents and the first chapter of all the books in our Book Series for free.

I look forward to meeting you this March!

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A focus on drug safety and efficacy

10 Feb 2014

Assessing and preventing adverse effects of pharmaceutical products is an important part of medicinal chemistry and drug development. The RSC Drug Discovery and Issues in Toxicology Series includes a broad range of books on drug efficacy and drug safety, or pharmacovigilance.

Take a look at the books below to find out more about issues involved in safety and efficacy of drugs and techniques for their evaluation. All these books are available as eBooks and you can access the front matter, table of contents and the first chapter of all these for free. Why not recommend them to your library?

These titles are a great resource for scientists involved in drug discovery and development and drug metabolism studies. They are also a valuable guide for regulators concerned with the safety evaluation of chemicals and postgraduate medicinal chemists.

Recently published:

Chemical Toxicity Prediction: Category Formation and Read-Across
Mark Cronin, Judith Madden, Steven Enoch and David Roberts (978-1-84973-384-7, Issues in Toxicology)

Comprehensive Biomarker Discovery and Validation for Clinical Application
Péter Horvatovich and Rainer Bischoff (978-1-84973-422-6, RSC Drug Discvovery)

More key texts:

Designing Multi-Target Drugs
J. Richard Morphy and C John Harris (978-1-84973-362-5, RSC Drug Discovery)

New Horizons in Predictive Toxicology: Current Status and Application
Alan G E Wilson (978-1-84973-051-8, RSC Drug Discovery)

Also highly recommended:

Cytochromes P450: Role in the Metabolism and Toxicity of Drugs and other Xenobiotics
Costas Ioannides (978-0-85404-274-6, Issues in Toxicology)

Nanostructured Biomaterials for Overcoming Biological Barriers
Maria Jose Alonso and Noemi S. Csaba (978-1-84973-363-2, RSC Drug Discovery)

Biomedical Imaging: The Chemistry of Labels, Probes and Contrast Agents
Martin Braddock (978-1-84973-014-3, RSC Drug Discovery)

Metabolism, Pharmacokinetics and Toxicity of Functional Groups: Impact of Chemical Building Blocks on ADMET
Dennis A Smith (978-1-84973-016-7, RSC Drug Discovery)

Coming soon:

Metabolic Profiling: Disease and Xenobiotics

Martin Grootveld (9781849731638, Issues in Toxicology)

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Updates from the Issues in Toxicology and RSC Drug Discovery Series

16 Dec 2013

Check out these recently published new titles in the Issues in Toxicology Series…

The Carcinogenicity of Metals
Human risk through occupational and environmental exposure
Authored by Alan B. G. Lansdown

Chemical Toxicity Prediction
Category Formation and Read-Across
Authored by Mark Cronin, Judith Madden , Steven Enoch and David Roberts

Advances in Dermatological Sciences
Edited by Robert Chilcott and Keith R. Brain

Reducing, Refining and Replacing the Use of Animals in Toxicity Testing
Edited by Dave Allen and Mike D Waters

…And these recently published books in the RSC Drug Discovery Series…

Pain Therapeutics
Current and Future Treatment Paradigms
Edited by Charlotte Allerton

Inhibitors of Molecular Chaperones as Therapeutic Agents
Edited by Timothy D Machajewski and Zhenhai Gao

The first chapter and table of contents for all of the above are free to view.
To access any of our free content you need to register for a free personal RSC Publishing account, and then login using your details. You will find our registration page here ….

To briefly introduce myself, my name is Rowan Frame and I am delighted to have recently joined the Royal Society of Chemistry Books Team. I will be covering the role of Cara Sutton, the current Commissioning Editor for books in the Issues in Toxicology, RSC Drug Discovery and RSC Metallobiology Series, who will be taking maternity leave in 2014.

If you are interested in writing a book in one of these areas, please get in touch. I look forward to hearing from you!

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