Now Published in the RSC Drug Discovery Series
New Frontiers in Chemical Biology: Enabling Drug Discovery
Edited by Mark E. Bunnage, Executive Director, Worldwide Medicinal Chemistry, Pfizer Inc., UK
New Frontiers in Chemical Biology: Enabling Drug Discovery highlights a number of key areas of chemical biology that are of direct relevance to the field of drug discovery. The book illustrates the powerful role that chemical genetic and chemical proteomic approaches can play in interrogating biological mechanisms and developing a deeper understanding of how small molecules interact in more complex biological systems. The modulation of stem cell behaviour through small molecules is also discussed and the emerging field of epigenetics is highlighted through a review of the chemical biology of histones. An overview of chemologic approaches includes highlights from the areas of synthetic vaccines and oligonucleotide therapeutics, and additional chapters focus in more depth on Antibody Drug Conjugates and DNA-encoded chemical libraries.
The book will be a valuable resource for scientists both in industry and academia who are looking to raise their awareness of chemical biology and how it may enable future drug discovery.
http://www.rsc.org/shop/books/2010/9781849731256.asp
