Now Published in the Issues in Toxicology Series
In Silico Toxicology: Principles and Applications
Editors: Mark T. D. Cronin and Judith C. Madden
In Silico methods to predict toxicity are becoming increasingly important, particularly in light of European legislation such as REACH. The objective of this exemplary new book is to enable the reader to develop new and use existing, in silico methods to predict the toxicity and fate of chemicals. The book develops the theme in a logical sequence leading the reader through the retrieval and assessment of quality, of toxicological data and information, the calculation of descriptors and properties, the basis of statistical techniques for QSARs, the interpretation and validation of models for regulatory use, the mechanistic basis to modelling, as well as chemical grouping approaches and application of models for risk assessment. With contributions from recognised leaders and real-world case studies the book will be essential reading for toxicologists and modellers using in silico approaches to perform risk assessment for regulatory purposes.
http://www.rsc.org/shop/books/2010/9781849730044.asp
