The analysis of protein phosphorylation using mass spectrometry has lead to impressive progress in the field. Almost any concept of analytical proteomics by mass spectrometry can be exampled by protein phosphorylation analysis.
Protein Phosphorylation by Mass Spectrometry guides the reader through this prolific field by presenting a collection of personal views and selected examples which cover all the important principles with a focus on electrospray ionization mass spectrometry. It covers: phosphorylation analysis at the peptide, protein and proteome level; manual and automated data evaluation; phosphopeptide enrichment; quantitative aspects; element mass spectrometry; individual analytical strategies, and hints to useful internet resources.
Gathering together all the key information, Wolf Lehman (German Cancer Research Center) presents a powerful guide to understanding the analytical concepts of mass spectrometry and its use in protein analysis. Lehman has been working in this area for many years and has contributed greatly to the development of mass spectrometry as a tool in the qualitative and quantitative analysis of proteins in a discrete, dedicated, and systematic manner.
Students and experienced researchers alike will benefit from the knowledge and method presented in this book.
Keen to learn more? Why not read the preface?
