Neglected Diseases and Drug Discovery

Now Published in the RSC Drug Discovery Series

Neglected Diseases and Drug Discovery

Edited by Michael J. Palmer and Timothy N.C. Wells

There are ~8 million deaths every year from neglected tropical diseases in the underdeveloped world, whilst drug discovery focus and practice is only recently taking on greater urgency and embracing the latest technologies. The aim of this book is to present a state-of-the-art review of drug discovery in respect of neglected tropical diseases and to highlight best practice to guide ongoing drug discovery effort, to raise awareness and promote debate in neglected disease areas that still have unmet medical need.

The book sets out to make a critical appraisal of ongoing research with a focus on the key science that has led to breakthroughs, especially from a medicinal chemistry perspective. It covers in great depth current efforts in the malaria, trypanosomatid, flavivirus and tuberculosis fields. Additionally there is further emphasis on the ‘neglected’ neglected diseases notably diarrhea, helminths, HIV and lower respiratory tract infections.

Written by a team of experienced experts the book will prove to be an invaluable guide to successful practice in neglected tropical diseases highlighting ongoing and new drug discovery efforts. It will aid both researchers and the general reader, by summarising the key learning to date and provide a clear overview of the challenges that still remain.

http://www.rsc.org/shop/books/2011/9781849731928.asp

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