Now Published in the RSC Drug Discovery Series
Pharmaceutical Process Development: Current Chemical and Engineering Challenges
Edited by A. John Blacker and Michael T. Williams
This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In fifteen concise chapters the book covers such diverse subjects as route design and selection, the interface with medicinal chemistry, the importance of green chemistry, the design of safe chemical reactions, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation and an assessment of future trends and challenges.
The book will be essential reading for both graduate and postgraduate students interested in a career in the pharmaceutical industry. It informs them about the breadth of work currently carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. Within the pharmaceutical industry the book will be a useful training aid for scientists at the early stages of their career development.