Now Published in the RSC Drug Discovery Series
Extracellular and Intracellular Signaling
Edited by James D. Adams Jr. and Keith K. Parker
Intracellular cell signaling is a well-understood process, but extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are vital to the process and have been largely ignored in other literature. These are causative agents in hypertension, diabetes, heart disease, arthritis and many other types of diseases. Aimed at medical professionals and pharmaceutical specialists, this book integrates for the first time extracellular and intracellular signaling processes and offers a fresh perspective on new targets for drug development.
With contributions from leading international authorities, readers are introduced to new evidence that by alterations in toxic lifestyles you can reduce the incidence of disease. New approaches are presented on disease causation from the persective of toxic lifestyles and the accumulation of toxic proteins and lipids. New therapeutic targets involving adipokines, ceramide and endocannabinoids are also discussed. The book will be essential reading for medical professionals, pharmaceutical specialists, molecular and cell biologists, biochemists, pharmacologists and medicinal chemists.