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HOT articles in Analyst

Take a look at our new HOT articles just published in Analyst and free for you for the next couple of weeks: Graphical abstract: Quantum dots in diagnostics and detection: principles and paradigms

Quantum dots in diagnostics and detection: principles and paradigms
T. R. Pisanic II, Y. Zhang and T. H. Wang
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00294F, Tutorial Review

Cotton fabric-based electrochemical device for lactate measurement in saliva
Radha S. P. Malon, K. Y. Chua, Dedy H. B. Wicaksono and Emma P. Córcoles
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00201F, Paper

Flow cytometric microsphere-based immunoassay as a novel non-radiometric method for the detection of glutamic acid decarboxylase autoantibodies in type 1 diabetes mellitus
Luciano L. Guerra, Aldana Trabucchi, Natalia I. Faccinetti, Ruben F. Iacono, Daniela B. Ureta, Edgardo Poskus and Silvina N. Valdez
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02243A, Paper

Enhanced Raman multigas sensing – a novel tool for control and analysis of 13CO2 labeling experiments in environmental research
Robert Keiner, Torsten Frosch, Tara Massad, Susan Trumbore and Jürgen Popp
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN01971C, Paper

Simple sample processing enhances malaria rapid diagnostic test performance
K. M. Davis, L. E. Gibson, F. R. Haselton and D. W. Wright
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00338A, Paper

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HOT articles in Analyst

Take a look at our new HOT articles just published in Analyst and free for you for the next couple of weeks: Graphical abstract: An electrochemiluminescent microRNA biosensor based on hybridization chain reaction coupled with hemin as the signal enhancer

Fabrication of disposable electrochemical devices using silver ink and office paper
W. R. de Araujo and T. R. L. C. Paixão
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00097H, Paper

A hybrid paper and microfluidic chip with electrowetting valves and colorimetric detection
Fei He, Jeff Grimes, Samuel D. Alcaine and Sam R. Nugen
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN01516E, Paper

An electrochemiluminescent microRNA biosensor based on hybridization chain reaction coupled with hemin as the signal enhancer
Pu Zhang, Xiaoyan Wu, Yaqin Chai and Ruo Yuan
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00284A, Paper

Investigating drug induced changes in single, living lymphocytes based on Raman micro-spectroscopy
Iwan W. Schie, Lucas Alber, Amy L. Gryshuk and James W. ChanGraphical abstract: Characterization of biofluids prepared by sessile drop formation
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00250D, Paper

Single vs. two-photon microscopy for label free intrinsic tissue studies in the UV light region
Vitalijs Zubkovs, Frédéric Jamme, Slavka Kascakova, Franck Chiappini, François Le Naour and Matthieu Réfrégiers
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00203B, Communication

Characterization of biofluids prepared by sessile drop formation
Karen A. Esmonde-White, Francis W. L. Esmonde-White, Michael D. Morris and Blake J. Roessler
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02175K, Paper

DNA hybridization detection with 100 zM sensitivity using piezoelectric plate sensors with an improved noise-reduction algorithm
Ceyhun E. Kirimli, Wei-Heng Shih and Wan Y. Shih
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00215F, Paper

Detection of zeptomole quantities of nonfluorescent molecules in a 101 nm nanochannel by thermal lens microscopy
T. H. H. Le, K. Mawatari, H. Shimizu and T. Kitamori
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00344F, Paper Graphical abstract: Detection of zeptomole quantities of nonfluorescent molecules in a 101 nm nanochannel by thermal lens microscopy

Microfluidic-SERS devices for one shot limit-of-detection
Donghyuk Kim, Antonio R. Campos, Ashish Datt, Zhe Gao, Matthew Rycenga, Nathan D. Burrows, Nathan G. Greeneltch, Chad A. Mirkin, Catherine J. Murphy, Richard P. Van Duyne and Christy L. Haynes
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00357H, Paper

Touch spray mass spectrometry for in situ analysis of complex samples
Kevin S. Kerian, Alan K. Jarmusch and R. Graham Cooks
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00548A, Paper

Criteria for sensitivity enhancement by compressed sensing: practical application to anisotropic NAD 2D-NMR spectroscopy
Krzysztof Kazimierczuk, Olivier Lafon and Philippe Lesot
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00381K, Paper

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HOT articles in Analyst

Take a look at our new HOT articles just published in Analyst and free for you for the next couple of weeks: Graphical abstract: Electrochemiluminescence resonance energy transfer between graphene quantum dots and gold nanoparticles for DNA damage detection

Electrochemiluminescence resonance energy transfer between graphene quantum dots and gold nanoparticles for DNA damage detection
Qian Lu, Wei Wei, Zhenxian Zhou, Zhixin Zhou, Yuanjian Zhang and Songqin Liu
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00020J, Paper

A lateral flow paper microarray for rapid allergy point of care diagnostics
Thiruppathiraja Chinnasamy, Loes I. Segerink, Mats Nystrand, Jesper Gantelius and Helene Andersson Svahn
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN01806G, Paper

Nanoparticles in sensing applications: on what timescale do analyte species adsorb on the particle surface?
Enno Kätelhön and Richard G. Compton
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00363B, Paper

The use of EEM fluorescence data and OPLS/UPLS-DA algorithm to discriminate between normal and cancer cell lines: a feasibility study
Ana Carolina de Oliveira Neves, Raimundo Fernandes de Araújo Júnior, Ana Luiza Cabral de Sá Leitão Oliveira, Aurigena Antunes de Araújo and Kássio Michell Gomes de Lima Graphical abstract: A lateral flow paper microarray for rapid allergy point of care diagnostics
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00296B, Paper

Enhancing permanganate chemiluminescence detection for the determination of glutathione and glutathione disulfide in biological matrices
Zoe M. Smith, Jessica M. Terry, Neil W. Barnett, Laura J. Gray, Dean J. Wright and Paul S. Francis
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00255E, Paper

Mass spectrometric investigation of the role of the linking polypeptide chain in DNA polymerase I
Taeho Yeom, Jungyoon Lee, Seonghyun Lee, Sunah Kang, Kyung Rok Kim, Byungwoo Han, Hyun Soo Lee and Kyubong Jo
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00107A, Paper

Optimizing detection of RDX vapors using designed experiments for remote sensing
Robert G. Ewing, Alejandro Heredia-Langner and Marvin G. WarnerGraphical abstract: Nanoparticles in sensing applications: on what timescale do analyte species adsorb on the particle surface?
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00125G, Paper

Mixed hydrogel bead-based tumor spheroid formation and anticancer drug testing
Yaolei Wang and Jinyi Wang
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00015C, Paper

Carbon nanobelts as a novel sensing platform for fluorescence-enhanced DNA detection
Xuping Sun, Zhicai Xing, Rui Ning, Abdullah M. Asiri and Abdullah Y. Obaid
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02364H, Communication

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Analytical tools made from ordinary office paper

Commonplace equipment can turn office paper into cheap, portable and disposable electrochemical devices that are ideal for using in remote locations.

The simple sensors from William de Araujo and Thiago da Paixão at the University of São Paulo, Brazil combine silver ink with ordinary office paper. Office paper is 97% cheaper than the chromatography paper commonly used in cutting-edge paper-based sensors.

To read the full article by Hazel Neighbour, please go to Chemistry World.

Fabrication of disposable electrochemical devices using silver ink and office paper
William Araujo and Thiago Regis Longo Cesar Paixão
Analyst, 2014, Accepted Manuscript
DOI: 10.1039/C4AN00097H, Paper

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HOT articles in Analyst

Take a look at our new HOT articles just published in Analyst and free for you for the next couple of weeks: Graphical abstract: Improving the fluorescence detection limit with positively charged carbon nanostructures as a low background signal platform

Recent advances in sample preparation techniques to overcome difficulties encountered during quantitative analysis of small molecules from biofluids using LC-MS/MS
Caroline Bylda, Roland Thiele, Uwe Kobold and Dietrich A. Volmer
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00094C, Minireview

Convenient detection of the thiol functional group using H/D isotope sensitive Raman spectroscopy
Sabyasachi Bandyopadhyay and Abhishek Dey
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02166A, Communication

Improving the fluorescence detection limit with positively charged carbon nanostructures as a low background signal platform
Xiulan He, Li Zhang, Hetong Qi, Ping Yu, Junjie Fei and Lanqun Mao
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00124A, Communication

Femtoliter-scale separation and sensitive detection of nonfluorescent samples in an extended-nano fluidic device
Hisashi Shimizu, Kazuma Mawatari and Takehiko Kitamori
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02353B, Paper

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HOT articles in Analyst

Take a look at our new HOT articles just published in Analyst and free for you for the next couple of weeks: Graphical abstract: Viral plaque analysis on a wide field-of-view, time-lapse, on-chip imaging platform

Viral plaque analysis on a wide field-of-view, time-lapse, on-chip imaging platform
Chao Han and Changhuei Yang
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02323K, Paper

IR action spectroscopy shows competitive oxazolone and diketopiperazine formation in peptides depends on peptide length and identity of terminal residue in the departing fragment
L. J. Morrison, J. Chamot-Rooke and V. H. Wysocki
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00064A, Paper

Energy-resolved collision-induced dissociation pathways of model N-linked glycopeptides: implications for capturing glycan connectivity and peptide sequence in a single experiment
Venkata Kolli and Eric D. Dodds
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02342G, Paper

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HOT articles in Analyst

Take a look at our new HOT articles just published in Analyst and free for you for the next couple of weeks: Graphical abstract: Live-cell vibrational imaging of choline metabolites by stimulated Raman scattering coupled with isotope-based metabolic labeling

Live-cell vibrational imaging of choline metabolites by stimulated Raman scattering coupled with isotope-based metabolic labeling
Fanghao Hu, Lu Wei, Chaogu Zheng, Yihui Shen and Wei Min
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02281A, Communication

Chip based single cell analysis for nanotoxicity assessment
Pratikkumar Shah, Ajeet Kaushik, Xuena Zhu, Chengxiao Zhang and Chen-Zhong Li
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02280C, Minireview

Chemical imaging of artificial fingerprints by desorption electro-flow focusing ionization mass spectrometry
Thomas P. Forbes and Edward Sisco
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00172A, Communication

Binding assay for low molecular weight analytes based on reflectometry of absorbing molecules in porous substrates
Milena Stephan, Corinna Kramer, Claudia Steinem and Andreas Janshoff
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00009A, Paper

Quantized double layer charging of Au130(SR)50 nanomoleculesGraphical abstract: Chemical imaging of artificial fingerprints by desorption electro-flow focusing ionization mass spectrometry
Vijay Reddy Jupally, Jacob G. Thrasher and Amala Dass
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02204H, Communication

Robotic plasma probe ionization mass spectrometry (RoPPI-MS) of non-planar surfaces
Rachel V. Bennett, Ezequiel M. Morzan, Jacob O. Huckaby, María Eugenia Monge, Henrick I. Christensen and Facundo M. Fernández
Analyst, 2014, Advance Article
DOI: 10.1039/C4AN00277F, Communication

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Shedding New Light on Old Treasures

Analytical techniques are shedding new light on old treasures.

Madame Leon Clapisson, 1883

Analytical chemists are making breakthroughs in the science of heritage and conservation. Using new techniques, previously lost nuances in the works of cultural artifacts are being rediscovered, enriching our understanding of our shared culture, and recasting our relationship with the past.

Dr Richard P. Van Duyne recently used Raman spectroscopy to reveal the stunning original colours of Renoir’s “Madame Valentine Clapisson” painted over a century ago. Using Surface Enhanced Raman Spectroscopy (SERS), a technique widely used in biomedical research that Van Duyne has spent the past few years adapting for the study of organic paints, the lush reds of the origiGraphical abstract: Mapping of egg yolk and animal skin glue paint binders in Early Renaissance paintings using near infrared reflectance imaging spectroscopynal could be acurately recreated. SERS involves adsorbing tiny paint samples to metal nanoparticles, which enhances the Raman signal so trace amounts of the pigment molecules can be detected. Routine art analysis techniques like x-ray fluorescence scanning are unsuitable for this kind of paint, as they rely on elemental signatures from metals, without Dr Van Duyne’s developments the original colours envisioned by Renoir would remain unknown.

In a recent themed collection in Analyst and Analytical Methods cutting edge developments in analytical science used in heritage and conservation were drawn together. Guest edited by Dr Francesca Casadio and Dr Richard P. Van Duyne, the collection of articles highlights work on historic buildings, illuminated manuscripts and paintings by artists such as Dali and Matisse, as well as developments on the underpinning analytical techniques that are revealing ground-breaking insights into our rich cultural heritage.

In their editorial, Dr Francesca Casadio and Dr Richard P. Van Duyne set out the case for the cooperation between the chemical sciences and heritage work, and highlight the need for future research into this area to guarantee the conservation and understanding of our shared history.

The collection is open for submissions. Submit your work to the collection, or read it online today.

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SPEC 2014

logo

The aim of this international conference series is to bring together clinicians and scientists who have joined forces in the quest for novel biomedical applications of Infrared and Raman spectroscopy to improve patient care. Recent advances in the biological sciences and medicine have led to an increasing demand for real time and minimally invasive chemical and structural information on biological materials. Due to its unique fingerprinting capability, vibrational spectroscopy plays a significant role in histopathology, cytology, biopsy targeting, surgical targets, treatment monitoring and drug studies. This, the 8th in the series, aims to highlight further advances in state of the art and emerging biomedical applications of Vibrational Spectroscopy, while critically reviewing the challenges in the context of other emerging technologies.

Date: 17-22 August 2014
Location: Krakow, Poland
Contact: Katarzyna Marzec
Email: marzec@chemia.uj.edu.pl
Website

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HOT articles in Analyst

Take a look at our new HOT articles just published in Analyst and free for you for the next couple of weeks: Graphical abstract: An antibody-free microfluidic paper-based analytical device for the determination of tear fluid lactoferrin by fluorescence sensitization of Tb3+

An antibody-free microfluidic paper-based analytical device for the determination of tear fluid lactoferrin by fluorescence sensitization of Tb3+
Kentaro Yamada, Shunsuke Takaki, Nobutoshi Komuro, Koji Suzuki and Daniel Citterio
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN01926H, Paper

Protein binding for detection of small changes on a nanoparticle surface
Shang Zeng, Yu-ming M. Huang, Chia-en A. Chang and Wenwan Zhong
Analyst, 2014,139, 1364-1371
DOI: 10.1039/C3AN02155F, Paper

Proteomic evaluation of citrate-coated silver nanoparticles toxicity in Daphnia magna
Louis-Charles Rainville, Darragh Carolan, Ana Coelho Varela, Hugh Doyle and David Sheehan
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02160B, Paper

Oxidized polyethylene films for orienting polar molecules for linear dichroism spectroscopy
Kasra Razmkhah, Nikola Paul Chmel, Matthew I. Gibson and Alison Rodger
Analyst, 2014,139, 1372-1382
DOI: 10.1039/C3AN02322B, Paper Graphical abstract: Making a big thing of a small cell – recent advances in single cell analysis

Solid-phase extraction and purification of membrane proteins using a UV-modified PMMA microfluidic bioaffinity μSPE device
Katrina N. Battle, Joshua M. Jackson, Małgorzata A. Witek, Mateusz L. Hupert, Sally A. Hunsucker, Paul M. Armistead and Steven A. Soper
Analyst, 2014,139, 1355-1363
DOI: 10.1039/C3AN02400H, Paper

Non-invasive mouthguard biosensor for continuous salivary monitoring of metabolites
Jayoung Kim, Gabriela Valdés-Ramírez, Amay J. Bandodkar, Wenzhao Jia, Alexandra G. Martinez, Julian Ramírez, Patrick Mercier and Joseph Wang
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN02359A, Paper

Making a big thing of a small cell – recent advances in single cell analysis
Kerstin Galler, Katharina Bräutigam, Christina Große, Jürgen Popp and Ute Neugebauer
Analyst, 2014,139, 1237-1273
DOI: 10.1039/C3AN01939J, Critical Review

Advances in nanowire transistors for biological analysis and cellular investigation
Bor-Ran Li, Chiao-Chen Chen, U. Rajesh Kumar and Yit-Tsong Chen
Analyst, 2014, Advance Article
DOI: 10.1039/C3AN01861J, Critical Review

High resolution magic angle spinning NMR as a tool for unveiling the molecular enantiorecognition of omeprazole by amylose-based chiral phase
Juliana Cristina Barreiro, Tiago de Campos Lourenço, Lorena Mara A. Silva, Tiago Venâncio and Quezia Bezerra Cass
Analyst, 2014,139, 1350-1354
DOI: 10.1039/C3AN02029K, Paper Graphical abstract: Intra-molecular reactions as a new approach to investigate bio-radical reactivity: a case study of cysteine sulfinyl radicals

Intra-molecular reactions as a new approach to investigate bio-radical reactivity: a case study of cysteine sulfinyl radicals
Kirt L. Durand, Xiaoxiao Ma and Yu Xia
Analyst, 2014,139, 1327-1330
DOI: 10.1039/C3AN02307A, Communication

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