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HOT Articles in Analyst

18 Sep 2013

Take a look at these new HOT articles just published in Analyst! These papers will be free to read for the next three weeks. Download them today!

The global identification of tRNA isoacceptors by targeted tandem mass spectrometry
Collin Wetzel and Patrick A. Limbach
Analyst, 2013,138, 6063-6072
DOI: 10.1039/C3AN01224G

Extraction and separation of proteins by ionic liquid aqueous two-phase system
Xiao Lin, Yuzhi Wang, Qun Zeng, Xueqin Ding and Jing Chen
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01301D

A smart T1-weighted MRI contrast agent for uranyl cations based on a DNAzyme–gadolinium conjugate
Weichen Xu, Hang Xing and Yi Lu
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01182H

Improved analysis of oligosaccharides for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using aminopyrazine as a derivatization reagent and a co-matrix
Yan Cai, Ying Zhang, Pengyuan Yang and Haojie Lu
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01228J

A chemical quenching- and physical blocking-based method to minimize process-mediated aggregation of antibody-crosslinked nanoparticles for imaging application
Chandra K. Dixit, Shibsekhar Roy, Conor Byrne, Richard O’Kennedy and Colette McDonagh
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01294H

Exploring the electrochemical performance of graphitic paste electrodes: graphene vs. graphite
Luiz C. S. Figueiredo-Filho, Dale A. C. Brownson, Maria Gómez-Mingot, Jesús Iniesta, Orlando Fatibello-Filho and Craig E. Banks
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00950E

An investigation into the simultaneous enzymatic and SERRS properties of silver nanoparticles
Kristy S. McKeating, Sian Sloan-Dennison, Duncan Graham and Karen Faulds
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01451G

Electrochemical piezoelectric-excited millimeter-sized cantilever (ePEMC) for simultaneous dual transduction biosensing
Blake N. Johnson and Raj Mutharasan
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01353G

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Bacteria incriminated by their odour

12 Sep 2013

Researchers in Taiwan and the US have developed a device that uses the volatile organic compounds released by bacteria to identify the bacteria as they are cultured. When fully developed, this single-step gadget could trump the speed of current clinical techniques.

Sepsis and other bloodstream infections are very dangerous and need immediate treatment. It is therefore essential to detect microorganisms in human blood quickly to decide the most effective treatment.

Blood cultures are currently used to detect if bacteria are present in a patient’s blood. This takes 24 hours or more just to reveal if a sample contains bacteria. Further tests reveal the identity of the bacteria and show which antibiotics can kill them. This multi-step process can take several days, and in the meantime patients are often treated with antibiotics presumptively, which can induce side effects in the patient as well as antibiotic resistance in the bacteria.

Chemometric analysis of colour changes reveals which strain of bacteria is present

To read the full article, please visit Chemistry World.

Single step, rapid identification of pathogenic microorganisms in a culture bottle
Yu W. Chu, Bo Y. Wang, David A. Engebretson and James R. Carey
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01175E

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A biochemical eyewitness

10 Sep 2013

Blood found at a crime scene could give police an indication of a criminal suspect’s ethnicity there and then thanks to a new bioassay.

Biological samples recovered at crime scenes can provide vital evidence to identify, accuse and exonerate. DNA/RNA analysis techniques for profiling suspects are sophisticated, but usually require complex equipment. On-site analysis of fluids is mostly limited to simple identification of possible samples, such as bloodstains, which are then collected and transported to specialist laboratories. This creates undesirable delays for investigations, where time is often of the essence.

To read the full article, please visit Chemistry World.

Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American groups
Friederike Kramer, Lenka Halámková, Arshak Poghossian, Michael J. Schöning, Evgeny Katz and Jan Halámek
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01062G

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HOT Articles in Analyst

10 Sep 2013

Take a look at these new HOT articles just published in Analyst! These papers will be free to read for the next two weeks. Click on the links below:

A new turn-on fluorescent chemosensor based on diketopyrrolopyrrole (DPP) for imaging Zn²⁺ in living cells
Guanjun Zhang, Haiying Li, Shiming Bi, Longfeng Song, Yunxiang Lu, Liang Zhang, Jianjun Yu and Limin Wang
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00873H

Separation of metalloproteins using a novel metal ion contaminant sweeping technique and detection of protein-bound copper by a metal ion probe in polyacrylamide gel electrophoresis: distribution of copper in human serum
Shingo Saito, Mitsuyoshi Kawashima, Hiroki Ohshima, Kazuki Enomoto, Makoto Sato, Hajime Yoshimura, Keitaro Yoshimoto, Mizuo Maedad and Masami Shibukawaa
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01107K

High pressure nanoelectrospray ionization mass spectrometry for analysis of aqueous solutions
Md. Matiur Rahman, Mridul Kanti Mandal, Kenzo Hiraoka and Lee Chuin Chen
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00699A

Introducing novel amorphous carbon nanoparticles as energy acceptors into a chemiluminescence resonance energy transfer immunoassay system
Zhenxing Wang, Hongfei Gao and Zhifeng Fu
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01177A

The global identification of tRNA isoacceptors by targeted tandem mass spectrometry
Collin Wetzel and Patrick A. Limbach
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01224G

Enhanced imaging of developed fingerprints using mass spectrometry imaging
M. J. Bailey, M. Ismail, S. Bleay, N. Bright, M. Levin Elad, Y. Cohen, B. Geller, D. Everson, C. Costa, R. P. Webb, J. F. Watts and M. de Puit
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01204B

Photonic crystal enhanced microscopy for imaging of live cell adhesion
Weili Chen, Kenneth D. Long, Meng Lu, Vikram Chaudhery, Hojeong Yu, Ji Sun Choi, James Polans, Yue Zhuo, Brendan A. C. Harley and Brian T. Cunningham
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01541F

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Advances in GC IV, Cheshire

04 Sep 2013

Advances in GC IV
30th October 2013 (First Announcement)
LGC Ltd, The Heath Business Park, Runcorn, Cheshire

Joint meeting organised by The Chromatographic Society and the North West Region of the Analytical Division of the Royal Society of Chemistry.

After the success of the 2011 meeting we are pleased to announce another follow up meeting in the series.
GC is still technique of choice for analysing both volatile and semi volatile compounds, but as we move to more difficult matrices, more is being asked of the technique in terms of separation and limits of detection. The meeting sets out to both give an overview of current GC technologies and methodologies, information on newer detection/separation solutions and case studies from all the main user areas.

In parallel to the full meeting program will be an Instrument exhibition with representatives from all the major GC Instrument and Consumables Suppliers.

For more information please contact Alan Handley.
Tel 01928 513681

Mobile 07917416529
E-mail: alan.handley@lgcgroup.com

Advances in GC IV – Topics and Speakers

09:15- 09:50        Registration ,Coffee and Exhibition

09:50-10:00         Opening and Welcome
                              Alan Handley (LGC Ltd)

10:00-10:40         Sample Preparation solutions for Gas Chromatography
                               Ray Perkins (Anatune)

10:40-11:20         Column Selection – there more to life than a boiling point column
                               Jaap de Zeeuw (Restek)

11:20 –12:00       Demystifying Comprehensive GC
                               Prof Jean-Francois Focant (University of Liege)

Exhibition and Lunch

14:00 -14:40        A fresh approach to managing GC in your Laboratory
                               Greg Johnson (Thermo Fisher)

14:40 – 15:20       Exploring the extra dimension – Getting more out of your GC Analysis
                                Ken Brady (Agilent)

15:20 – 15:35       Coffee

15:35 – 16:05       What has Deconvolution ever done for us?
                                Neil Owen (Givaudan UK Ltd)

16:05 – 16:35       Are GC techniques comparable to the human nose?
                                Lewis Jones (Mars Waltham)

16:35                     Close of meeting

Registration (Includes all sessions, exhibition and lunch)

Members of either The Chromatographic Society, RSC or BMSS                 £60

Non Members                                                                                                          £80

Students* and Retired                                                                                            £10
*Student bursaries for travel are available please contact Alan Handley

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3rd Workshop on Microfludics, Sao Paulo, Brazil

27 Aug 2013

The 3rd Workshop on Microfluidics was held at the National Center for Research on Energy and Materials (CNPEM) in Campinas, Sao Paulo (Brazil) from July 18-19, 2013. Since 2011, the workshop has brought together young students, researchers and companies from different states of Brazil to discuss topics related to the fundamentals, fabrication technologies, innovations and applications on microfluidic science. In this third edition, the Workshop was attended by around 160 people from Universities (66%), research centers (23%) and companies (11%). As already observed in previous years, the Workshop has demonstrated the state of the art of microfluidics in Brazil. This field has been spread out around different regions of the Brazil with great contributions on fabrication technologies well as innovative developments and applications on microfluidic platforms. For the coming years, we hope that the Workshop will continue to receive great attention from the community in order to contribute to the scientific growth related to the microfluidics in Brazil.

During the Workshop, we were pleased to select the presentation “Microfluidic formation of pDNA/cationic nonviral nanocarriers for in vitro gene delivery” to receive the RSC Publishing Prize for the best presentation. The work was presented by the graduated student Tiago A. Balbino and was supervised by Dr. Lucimara G. de La Torre, from the School of Chemical Engineering, State University of Campinas (UNICAMP). The work describes the microfluidic formation of nonviral systems for delivery of plasmid DNA (pDNA) using a hydrodynamic flow-focusing microfluidic device where the complexation between the pDNA and three different cationic nonviral nanocarriers: cationic liposomes, poly(ethylene imine), and peptide with nuclear localization signals were demonstrated.
On behalf of the organizing committee, I would like to thank the support received from the Royal Society of Chemistry.

Angelo Luiz Gobbi

Microfabrication Laboratory – LNNano

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HOT Articles in Analyst

20 Aug 2013

Check out the latest HOT articles just published in Analyst! They are all free for you to read for the next three weeks. Enjoy!

A protein nanofiber hydrogel for sensitive immunoassays
Dae-Sung Lee, Jin-Seung Park, Eun Jung Lee, Hyun Jin Kim and Jeewon Lee
Analyst, 2013,138, 4786-4794
DOI: 10.1039/C3AN00564J

Anodic stripping voltammetric determination of cadmium using a “mercury free” indium film electrode
Sukeri Anandhakumar, Jayaraman Mathiyarasu and Kanala Lakshimi Narasimha Phani
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01070H

Alteration of Asian lacquer: in-depth insight using a physico-chemical multiscale approach
Anne-Solenn Le Hô, Chloé Duhamel, Céline Daher, Ludovic Bellot-Gurlet, Céline Paris, Martine Regert, Michel Sablier, Guilhem André, Jean-Paul Desrochese and Paul Dumasf
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00608E

Luminescence lifetime-based capillary oxygen sensor utilizing monolithically integrated organic photodiodes
Bernhard Lamprecht, Andreas Tschepp, Merima Cajlakovic, Martin Sagmeister, Volker Ribitsch and Stefan Köstler
Analyst, 2013, Accepted Manuscript
DOI: 10.1039/C3AN00208J

Dual detection of cancer biomarker CA125 using absorbance and electrochemical methods
Israa Al-Ogaidi, Zoraida P. Aguilar, Savan Suri, Honglei Gou and Nianqiang Wu
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00668A

Desorption electro-flow focusing ionization of explosives and narcotics for ambient pressure mass spectrometry
Thomas P. Forbes, Tim M. Brewer and Greg Gillen
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01164J

High-throughput analysis of drugs in biological fluids by desorption electrospray ionization mass spectrometry coupled with thin liquid membrane extraction Cecilie Rosting, Stig Pedersen-Bjergaard, Steen Honoré Hansen and Christian Janfelt
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00544E

Multifunctional carbon nanoelectrodes fabricated by focused ion beam milling
Rahul Thakar, Anna E. Weber, Celeste A. Morris and Lane A. Baker
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01216F

Facile synthesis of quantum dots/mesoporous silica/quantum dots core/shell/shell hybrid microspheres for ratiometric fluorescence detection of 5-fluorouracil in human serum
Rijun Gui, Ajun Wan and Hui Jin
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01089A

Optimization of microfluidic PET tracer synthesis with Cerenkov imaging
Alex A. Dooraghi, Pei Y. Keng, Supin Chen, Muhammad R. Javed, Chang-Jin “CJ” Kim, Arion F. Chatziioannou and R. Michael van Dam
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01113E

A label-free and colorimetric turn-on assay for coralyne based on coralyne-induced formation of peroxidase-mimicking split DNAzyme
Ting Hou, Xiuzhong Wang, Xiaojuan Liu, Shufeng Liu, Zongfeng Du and Feng Li
Analyst, 2013,138, 4728-4731
DOI: 10.1039/C3AN01024D

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A fantastic voyage

15 Aug 2013

Joseph Wang is a Distinguished Professor and Vice Chair of Nanoengineering at the University of California, San Diego in the US. His research looks at the rapidly developing field of nanobioelectronics which aims to integrate nano- and biomaterials with electronic transducers. He took some time out from the Faraday Discussion on Electroanalysis at the Nanoscale, held at the University of Durham, UK, at the beginning of July, to talk to Rebecca Brodie about his research.

Who or what inspired you to become a scientist in the first place?

I’ve always been interested in science. More biology and medicine in the early days but it was mainly an interest in medicine and biomedicine. After that I became a chemist, then an electrochemist with my PhD. It’s really been a continuous evolution with my interests moving in new directions for almost three decades now.

To read the full article, please visit Chemistry World.

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Mercury 2013 – RSC Award and themed collection

13 Aug 2013

RSC journals were delighted to support the recent International Conference on Mercury as a Global Pollutant which was held in Edinburgh, UK. Congratulations to James Goacher from University of Western Ontario in London, Canada, who was awarded the RSC Best Student Presentation Award in the field of analytical methodology, environmental monitoring and assessment.

James is currently studying at the University of Western Ontario in London, Canada. He began his academic journey by completing a fourth year honours thesis project in the same field and went on to win best thesis presentation for his work. James then began an MSc to focus on historical trends in mercury accumulation in remote peatlands of far Northern Ontario in the Hudson Bay Lowland. This environmentally sensitive area is expected to be subject to some of the greatest climate related changes in the coming future and James feels strongly that area needs to be well understood and protected for its inherent value. By better understanding historical mercury trends in the natural environment, James hopes to tease apart current anthropogenic influences on the mercury cycle so that realistic emissions targets can be set. Future plans for James are still uncertain, but he expects his passion for the environment will lead him on to improve Canadian environmental policy and practises.

We are also pleased to announce that the following RSC journals will be publishing a cross journal web-themed issue relating to papers presented at Mercury 2013:

Analytical Methods – Early applied demonstrations of new analytical methods with clear societal impact

JAAS – Innovative research on the fundamental theory and application of spectrometric techniques

Metallomics – A global approach to metals in biology

Environmental Science: Processes and Impacts – advancing our understanding of environmental hazards, processes, and impacts, and offer solutions to today’s and future problems, formerly the Journal of Environmental Monitoring,

RSC Advances – An international journal to further the chemical sciences

Authors from the participating sessions are invited to submit to the journal most suitable for their work. The relevant articles from the conference will be published in those journals and then collected together as a joint web collection, as a permanent record of the conference. Articles submitted to the participating journals will be reviewed in the usual manner, and also appear in a normal issue both online and in print.

The submission deadline for our web theme will be September 24th 2013 with the view of final publication in January 2014. Specific information on the scope of each journal and author submission instructions can be found on the journal homepages.

We look forward to receiving your submission!

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HOT Articles in Analyst

25 Jul 2013

Take a look below at the new HOT Articles just published in Analyst. They will be free to read until August 16th. Enjoy!

Multiplexed DNA detection with a composite molecular beacon based on guanine-quenching
Dong-Shan Xiang, Kun Zhai and Lian-Zhi Wang
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01060K

In vivo characterization of protein uptake by yeast cell envelope: single cell AFM imaging and μ-tip-enhanced Raman scattering study
Denys Naumenko, Valentinas Snitka, Elena Serviene, Ingrida Bruzait and Boris Snopok
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00362K

Luminol-labeled gold nanoparticles for ultrasensitive chemiluminescence-based chemical analyses
Lateef U. Syed, Luxi Zhang Swisher, Hannah Huff, Caitlin Rochford, Fengli Wang, Jianwei Liu, Judy Wu, Mark Richter, Sivasai Balivada, Deryl Troyer and Jun Li
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01005H

Toward optimal spatial and spectral quality in widefield infrared spectromicroscopy of IR labelled single cells
Eric C. Mattson, Miriam Unger, Sylvain Clède, François Lambert, Clotilde Policar, Asher Imtiaz, Roshan D’Souza and Carol J. Hirschmugl
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00383C

Energy-selective neutron imaging for morphological and phase analysis of iron–nickel meteorites
S. Peetermans, F. Grazzi, F. Salvemini, E. H. Lehmann, S. Caporalid and G. Pratesie
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00985H

Metal–tag labeling coupled with multiple reaction monitoring-mass spectrometry for absolute quantitation of proteins
Xueying Wang, Xin Wang, Weijie Qin, Hongjun Lin, Jifeng Wang, Junying Wei, Yangjun Zhang and Xiaohong Qian
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00613A

A novel miniaturized radiofrequency potentiometer tag using ion-selective electrodes for wireless ion sensing
Marta Novell, Tomàs Guinovart, Ivana Murković Steinberg, Matthew Steinberg, F. Xavier Rius and Francisco J. Andrade
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00727H

3D pulsed laser-triggered high-speed microfluidic fluorescence-activated cell sorter
Yue Chen, Ting-Hsiang Wu, Yu-Chun Kung, Michael A. Teitell and Pei-Yu Chiou
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN01266B

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Analyst Blog

Author Archive

HOT Articles in Analyst

Bacteria incriminated by their odour

A biochemical eyewitness

HOT Articles in Analyst

Advances in GC IV, Cheshire

3rd Workshop on Microfludics, Sao Paulo, Brazil

HOT Articles in Analyst

A fantastic voyage

Mercury 2013 – RSC Award and themed collection

HOT Articles in Analyst

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