Archive for June, 2013

What does it mean to be an “Analyst”?

The Thinker

The Thinker (from The Bubble Chamber blog)

There appears to be many journal titles that contain the word “analyst” in some form. Examples include Analytical Biochemistry, Analytical Chemistry, Analytica Chimica Acta, Analytica, Journal of Analytical Toxicology, Analytical Methods, and of course, Analyst.

With so many variations of analytical journals available, some effort is needed to determine the best fit when submitting a manuscript for publication. This process requires classification of your own area(s) of research, which can be surprisingly challenging.

Take for instance, the areas of biochemistry, chemical biology, and biological chemistry. The prefix of each word appears to form the suffix of the next, and vice versa. In fact, if all of these words are to be read one after another, the whole phrase sounds more like a tongue-twister! While each of these respective scientific fields is specialized in its own right, some ambiguity still remains upon deeper contemplation of what exactly each field encompasses and what it does not. Differences among the fields can become more difficult to discern, the boundaries that separate them become less defined, and these multi-disciplinary approaches begin to converge into common research goals.

An underlying factor that unifies various scientific areas is the requirement of high quality analysis.

So, what does it mean exactly to be an analyst? Perhaps it is someone who can decipher the fine details of chemical reactions, molecular structures, computational algorithms, and biochemical mechanisms; then piece together these components into an overall composite for scientific understanding. Perhaps it is someone who is well-attuned with his/her surroundings, and inspired to find answers to everyday peculiarities. It may be someone who foresees the raw potential in new discoveries, even before direct applications are demonstrated. Or simply someone who loves scientific questioning and appreciates the sake of learning for what it is worth in and of itself. Whatever the precise definition is, frequent publications and updates on the latest scientific breakthroughs by journals like Analyst continue to ignite the passion of those who are motivated to discover and to know more.

So what does being an Analyst mean to you? Share your thoughts with us by commenting below.

From discovery to recovery – Analyst and Analytical Methods working together for the analytical community
Analyst, 2011,136, 429-430
DOI: 10.1039/C0AN90013C

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The first reason to attend HPLC 2013 – Hobart

Listen and learn from Prof. Gert Desmet’s plenary presentation on

 ‘Pressures and Particles: How to Make the Best Choice

Then decrease the pressure and explore some of Tasmania’s own pristine particles, forming some of the world’s most beautiful white sandy beaches, including the mesmerising Bay of Fires (Lonely Planet’s World’s “Hottest” travel destination for 2012) and Tasmania’s iconic and stunning Wineglass bay.

This is a unique opportunity for you to meet with scientists from throughout the world and to share your latest results!

KEY DATE!
Abstract Deadline – 31st July 2013

Click here your abstract to be considered for the HPLC 2013 – Hobart Conference Program

For more information please visit the Conference website at http://www.hplc2013-hobart.org/

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HOT Articles in Analyst!

Take a look at our HOT papers just published in Analyst! They will be free to read until July 20th. To read the full articles, just click on the links below!

Ag-decorated TiO2 nanograss for 3D SERS-active substrate with visible light self-cleaning and reactivation
S. C. Xu, Y. X. Zhang, Y. Y. Luo, S. Wang,  H. L. Ding,  J. M. Xu and G. H. Li  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00750B

Potentiometric sensors using cotton yarns, carbon nanotubes and polymeric membranes
Tomàs Guinovart, Marc Parrilla, Gastón A. Crespo, F. Xavier Rius and Francisco J. Andrade   
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00710C

Cerium oxide-triggered ‘one-to-many’ catalytic cycling strategy for in situ amplified electronic signal of low-abundance protein
Juan Tang, Xian Chen, Jun Zhou, Qunfang Li, Guonan Chen and Dianping Tang 
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00706E

Single molecule kinetics of horseradish peroxidase exposed in large arrays of femtoliter-sized fused silica chambers Benno N. Ehrl, Raphael B. Liebherr and Hans H. Gorris 
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00809F

Detection of mRNA in living cells by double-stranded locked nucleic acid probes
Reza Riahi, Zachary Dean, Ting-Hsiang Wu, Michael A. Teitell, Pei-Yu Chiou, Donna D. Zhang and Pak Kin Wong  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00722G

A nanosized metal–organic framework of Fe-MIL-88NH2 as a novel peroxidase mimic used for colorimetric detection of glucose
Ya Li Liu, Xi Juan Zhao, Xiao Xi Yang and Yuan Fang Li  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00560G

A novel microfluidic mixer based on dual-hydrodynamic focusing for interrogating the kinetics of DNA–protein interaction
Ying Li,  Fei Xu, Chao Liu, Youzhi Xu, Xiaojun Feng and Bi-Feng Liu  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00521F

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Analyst’s latest Impact Factor: 4.0

We are delighted to announce that our latest Impact Factor* is 4.0

Analyst remains the home of premier fundamental discoveries, inventions and applications in the analytical and bioanalytical sciences and is in the top 3 general analytical journals publishing primary research.

The Editorial Office thanks all of our Board members, authors and readers for their continued support.

We invite you to submit your latest piece of high impact work with us here.

*The Impact Factor provides an indication of the average number of citations per paper. Produced annually, Impact Factors are calculated by dividing the number of citations in a year by the number of citeable articles published in the preceding two years. Data based on 2012 Journal Citation Reports®, (Thomson Reuters, 2013).

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HOT Articles in Analyst

Check out our latest HOT articles just published in Analyst! They are all free for you to read until July 8th. Enjoy!

Electrochemiluminescent polymer films with a suitable redox “turn-off” absorbance window for remote selective sensing of Hg2+
Qinghai Shu, Catherine Adam, Neso Sojic  and  Michael Schmittel  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00545C

A novel LTCC electrochemical cell construction and characterization: a detection compartment for portable devices
Naira Canevarolo Pesquero, Mário Ricardo Gongora-Rubio and  Hideko Yamanaka 
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00648D 

A rapid, topographical platelet activation assay
R. Woolley, Ú. Prendergast, B. Jose, D. Kenny and C. McDonagh 
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00046J 
 
Exploring the origins of the apparent “electrocatalytic” oxidation of kojic acid at graphene modified electrodes
Luiz C. S. Figueiredo-Filho, Dale A. C. Brownson, Orlando Fatibello-Filho and Craig E. Banks  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00856H

An iTRAQ based quantitative proteomic strategy to explore novel secreted proteins in metastatic hepatocellular carcinoma cell lines
Yanyan Yu, Xiuwen Pan, Ying Ding, Xiaohui Liu, Hailin Tang, Chengpin Shen, Huali Shen and Pengyuan Yang 
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00517H  

Synchrotron Fourier transform infrared (FTIR) analysis of single living cells progressing through the cell cycle
Donna R. Whelan, Keith R. Bambery, Ljiljana Puskar, Don McNaughton and Bayden R. Wood 
Analyst, 2013,138, 3891-3899
DOI: 10.1039/C3AN00316G

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A Combination Probe for Characterizing Cancerous Tissue

Instrument with a thin fibre optic Raman probe mounted inside a hollow tactile resonance sensor

In some types of cancers, such as in prostate cancers, surgical removal of the entire organ provides the most effective treatment option. Unfortunately, after removal of the prostate a few tumor cells may remain and cause a recurrence of the disease in the patient. If the surgical area could be tested shortly after removal, it would determine if any cancerous cells remain and improve patient mortality.

Morgan Nyberg and researchers at Umea University in Sweden have harnessed the power of two techniques in a single probe to differentiate healthy and cancerous cells: Raman spectroscopy and tactile resonance method (TRM). Although an inherently weak effect, Raman spectroscopy can identify tissues based on their unique vibrational spectra. TRM measures tissue stiffness and successfully detects cancerous tissues in a prostate. However, it fails at the cellular level in differentiating between other benign growth tissues from cancerous ones. The combination of these two techniques removes the drawbacks of implementing Raman spectroscopy in surgery such as interfering ambient light and increases the specificity lacking in TRM. The researchers have successfully identified muscle and fat tissues from an animal sample and plan to move onto prostate tissue samples in the near future.

To know more about this ressearch, please access the full article below. This paper will be free to read for the next three weeks.

Optical fibre probe NIR Raman measurements in ambient light and in combination with a tactile resonance sensor for possible cancer detection
Morgan Nyberg, Kerstin Ramser and   Olof A. Lindahl
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00243H

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Take 1.. minute for chemistry in health

Do you know how chemical scientists can tackle global challenges in Human Health? If so, the RSC is running a one minute video competition this summer for young researchers such as PhD and Post-doc students; get involved and innovate the way scientists share their research. Your video should communicate your own personal research or an area of research that interests you, highlighting its significance and impact to Human Health.

Five videos will be shortlisted by our judging panel and the winner will be selected during the ‘How does chemistry keep us healthy?’ themed National Chemistry Week taking place 16-23 November.

A £500 prize and a fantastic opportunity to shadow the award winning video Journalist, Brady Harran, is up for grabs for the winner.

The judging panel will include the makers of The Periodic Tale of Videos, Martyn Poliakoff and Brady Harran, and RSC Division representatives.

Check out our webpage for further details of the competition and an example video.

The competition will open 02 April 2013 and the closing date for entries is 01 July 2013. Please submit your entries to
rsc.li/take-1-video-competition.

Any questions please contact science@rsc.org.

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HOT Articles in Analyst

Enjoy our new selected HOT articles just published in Analyst! They will be free for you until July 1st. Have a read now!

An iTRAQ Based Quantitative Proteomic Strategy to Explore Novel Secreted Proteins in Metastatic Hepatocellular Carcinoma Cell Lines
Yanyan Yu, Xiuwen Pan, Ying Ding, Xiaohui Liu, Hailin Tang, Cheng-Pin Shen, Huali Shen and Pengyuan Yang  
Analyst, 2013, Accepted Manuscript
DOI: 10.1039/C3AN00517H 
 

Plasmon enhanced fluoro-immunoassay using egg yolk antibodies for ultra-sensitive detection of herbicide diuron
Priyanka Sharma, Manil Kakkar, Ashok Ganguli, Aman Bhasin and C Raman Suri  
Analyst, 2013, Accepted Manuscript
DOI: 10.1039/C3AN00505D 

A multi-parametric microarray for protein profiling: simultaneous analysis of 8 different cytochromes via differentially element tagged antibodies and laser ablation ICP-MS
Larissa Waentig, Sandra Techritz, Norbert Jakubowski and Peter H. Roos  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00468F

Aptamer based electrochemical biosensor for tumor necrosis factor-alpha detection in whole blood
Ying Liu, Qing Zhou and Alexander Revzin  
Analyst, 2013, Accepted Manuscript
DOI: 10.1039/C3AN00818E

Spectral histopathology of colon cancer tissue sections by Raman imaging with 532 nm excitation provides label free annotation of lymphocytes, erythrocytes and proliferating nuclei of cancer cells
Laven Mavarani, Dennis Petersen, Samir F. El-Mashtoly, Axel Mosig, Andrea Tannapfel, Carsten Köttinga and  Klaus Gerwert  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00370A 
 

Illuminating disease and enlightening biomedicine: Raman spectroscopy as a diagnostic tool
David I. Ellis, David P. Cowcher, Lorna Ashton, Steve O’Hagan and Royston Goodacrea  
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00698K

Nanoparticle embedded enzymes for improved lateral flow sensors
Veli C. Özalp, Uğur S. Zeydanlı, Anita Lunding, Murat Kavruk, M. Tufan Öz, Füsun Eyidoğan, Lars F. Olsen and Hüseyin A. Ökteme 
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00733B 
 

Surface-enhanced Raman spectroscopy studies of yellow organic dyestuffs and lake pigments in oil paint
Hannah E. Mayhew, David M. Fabian, Shelley A. Svoboda and Kristin L. Wustholz
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN00611E

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