Diagnosing bacterial growth

Antibiotics are used regularly for treating bacterial infections, but there is currently no quick and simple test to determine the most effective type or dose of antibiotic for a specific patient infection. As a result, it’s estimated that around 30% of all antibiotic prescriptions are not the optimum choice. This can lead to the formation of drug-resistant bacteria, delayed recovery, and in some cases death from an infection.

Tests for the most appropriate antibiotic choice are performed for life-threatening patient infections. However, microbes have to be grown on agar plates from a very small patient sample which delays results for a few days. Hiroaki Suzuki et al have designed a microfluidic device that is able to determine the most effective antibiotic treatment in just 12 hours.

 

To read the full article please visit Chemistry World.

A microfluidic microbial culture device for rapid determination of the minimum inhibitory concentration of antibiotics
Rika Takagi ,  Junji Fukuda ,  Keiji Nagata ,  Yutaka Yawata ,  Nobuhiko Nomura and Hiroaki Suzuki
Analyst, 2013,138, 1000-1003
DOI: 10.1039/C2AN36323B

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