A New Solution to an Old Problem – A Novel Microfluidic Device for Efficient DNA Separation

micro-nanofluidic device

Anselmetti et al., Analyst, 2013, Advance Article

We often hear the colloquial phrase, “if something isn’t broken, then why fix it?” However, with this line of thinking, we may at times overlook areas that need improvement, and miss out on opportunities to make a big difference. Routine methods for DNA separation such as gel electrophoresis, and capillary chromatography are so widely used that they are often thought of as standard techniques, despite their obvious limitations. Dario Anselmetti, and colleagues from Bielefeld University, Germany have sought out to find a better way for efficient detection, separation, and purification of different DNA topologies. They have developed a novel micro-nanofluidic device based on dielectrophoretic trapping to enable fast, continuous-flow, and virtually label-free DNA separation. Find out more about their discovery by accessing the link below:

Fast and continuous-flow separation of DNA-complexes and topological DNA variants in microfluidic chip format

Martina Viefhues,* Jan Regtmeier and Dario Anselmetti

Analyst, 2013, Advance Article

DOI:10.1039/c2an36056j

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