Archive for June, 2012

HOT article: Monitoring chicken meat freshness by colorimetric sensor

Scientists in Spain used an array of 16 chromogenic indicators with different chemical recognition properties to follow the ageing of chicken stored in modified atmosphere packaging (MAP).

Many currently available methods to check meat spoilage are destructive, time-consuming, expensive and require qualified personnel. This means that they are fine for food safety inspections, but not suitable for use in shops or on every piece of packaged meat. Chromogenic sensors are cheap, versatile, can be printed on packaging and easily measured by cameras or the naked eye. The team observed characteristic colour fingerprints for each day of the study (which was carried out over 12 days) and gave clear differentiation at two-day intervals.

Once the 16-dye array had been successfully used, the team developed a simpler version based on just two dyes with three categories allowing differentiation between ‘fresh’, ‘beginning of decay’ and ‘non-fresh’. This shortened version could be printed on packaging and observed by the naked eye.

Monitoring of chicken meat freshness by means of a colorimetric sensor array
Analyst
, 2012,
DOI: 10.1039/C2AN35211G

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HOT article: Saliva sample collector for non-invasive health test

Monitoring volatile organic compound (VOC) levels in workers exposed to these compounds is important for their health. This is normally done by taking blood samples. However, scientists are looking towards using saliva samples instead, as a non-invasive technique.

Collecting saliva samples is done by either passive drool (in which the subject has to sit tight while their saliva drips off their lips into a collection vessel) or by chewing on a piece of cotton wool (which is then centrifuged to collect the saliva). But, neither technique can be used to detect VOCs in saliva.

Now, UK scientists at Loughborough University and Unilever R&D in the Wirral have come up with a new approach to overcome this problem. They carried out sampling of VOCs directly in the mouth using a polydimethylsiloxane sampler.

Although it takes 10 minutes to collect a sample, the team says that they are working towards reducing the time to one minute. The method could be combined with other VOC sampling methods – breath and skin analysis – they say.

Sampling and Characterisation of Volatile Organic Compound Profiles in Human Saliva Using a Polydimethylsiloxane Coupon Placed Within the Oral Cavity
Analyst, 2012, Accepted Manuscript
DOI: 10.1039/C2AN35432B

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Robert Boyle Prize for Analytical Science announced

In this month’s issue of Analyst, we have a paper from Norman Dovichi, from the University of Notre Dame, USA, who has recently been announced as the recipient of the Robert Boyle Prize for Analytical Science for 2012 by the Royal Society of Chemistry. The prize was awarded for his pioneering development of ultrasensitive separations, including the first separations at zepto- and yoctomole levels and capillary electrophoresis-based DNA sequencing for the human genome.

If you are interested to hear about his work, Norman will be speaking at the RSC Symposium at Pittcon 2013, which is being held March 17 – 21, 2013, Pennsylvania Convention Center, Philadelphia, PA USA.

His recent paper in Analyst, is on the new design of a sheath flow cuvette that uses an inexpensive quartz cuvette. The sensitivity and performance was then tested using capillary electrophoresis and a laser-induced fluorescence detector. Click on the title below to read more.

Simplified sheath flow cuvette design for ultrasensitive laser induced fluorescence detection in capillary electrophoresisSimplified sheath flow cuvette design for ultrasensitive laser induced fluorescence detection in capillary electrophoresis
Oluwatosin O. Dada, Bonnie J. Huge and Norman J. Dovichi
Analyst, 2012, 137, 3099-3101
DOI: 10.1039/C2AN35321K

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HOT articles in Issue 13

Professor Pavel Matousek

Professor Pavel Matousek

In addition to the excellent themed issue collection on Single Entities, there are other high-profile names in the latest issue of Analyst.

Editorial Board member Pavel Matousek and collaborators employ transmission Raman spectroscopy for the first time to analyse model formulations comprising tabletted cocrystals.

Transmission Raman spectroscopy for quality control in model cocrystal tablets
Jonathan C. Burley, Aalae Alkhalil, Matthew Bloomfield and Pavel Matousek
Analyst, 2012, 137, 3052-3057
DOI: 10.1039/C2AN35216H

Another Editorial Board member, Graham Cooks, also features. In his paper, leaf spray mass spectrometry is explored as a fast and simple way for direct analysis of glycosides in Stevia leaves without sample pretreatment.

Professor Graham Cooks

Professor Graham Cooks

Direct analysis of steviol glycosides from Stevia leaves by ambient ionization mass spectrometry performed on whole leaves
J. Isabella Zhang, Xin Li, Zheng Ouyang and R. Graham Cooks
Analyst, 2012, 137, 3091-3098
DOI: 10.1039/C2AN16263F

There is also a collection of HOT papers to take a look at…

(more…)

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Issue 13 online: the ‘Single’ issue, Guest Edited by Henry S. White

Professor Henry S. White

Professor Henry S. White, Guest Editor

Unlucky for some, but not for Analyst: Issue 13 is now online and features papers from the ‘Single’ issue, guest edited by Professor Henry S. White from the University of Utah. The issue features some great articles from authors such as Jonathan Cooper, Zuzanna Siwy, Lane Baker and Jonathan Sweedler.

In his Editorial, Professor White highlights the wealth of information that there is to be gained when analytical chemistry is studied at the “single entity” level.

Editorial – Single Entities
Henry S. White
Analyst, 2012, 137, 2921-2921
DOI: 10.1039/C2AN90049A

The stunning front cover features a themed issue paper from Jonathan Cooper and colleagues from the University of Glasgow on the combination of microdroplet technology with cell-free cytoskeletal protein expression as tool for biological investigation.

Analyst, 2012, Vol 137, Issue 13, front cover

Front cover: Chanasakulniyom et al., Analyst, 2012, 137, 2939-2943

Expression of membrane-associated proteins within single emulsion cell facsimiles
Mayuree Chanasakulniyom, Chiara Martino, David Paterson, Louise Horsfall, Susan Rosser and Jonathan M. Cooper
Analyst, 2012, 137, 2939-2943
DOI: 10.1039/C2AN35047E

Featured on the colourful inside front cover is a themed issue paper from the group of Zuzanna Siwy of the University of California, Irvine, on single nanopores with a hydrophobic layer at the pore entrance gates, providing a way to control the transport of ions.

A hydrophobic entrance enhances ion current rectification and induces dewetting in asymmetric nanopores
Matthew Pevarnik, Ken Healy, Matthew Davenport, Joseph Yen and Zuzanna S. Siwy
Analyst, 2012, 137, 2944-2950
DOI: 10.1039/C2AN16139G

These cover articles will be free to access for 6 weeks.

Take a look at the other HOT papers from the themed issue:

(more…)

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HOT article: highly sensitive copper sensor using nanoparticles and DLS

Copper(II) sensor based on gold nanoparticles and dynamic light scattering

Miao et al., Analyst, 2012, Advance Article

This HOT article features work from Xintao Shuai and colleagues of Sun Yat-Sen University, Guangzhao, China.

They present a novel, sensitive Cu2+ sensor based on the use of dynamic light scattering (DLS) to detect difference in the hydrodynamic diameter of gold nanoparticles (AuNPs). The ability of DNA to adsorb on the AuNPs changes with the presence of Cu2+, affecting the disperse state of the AuNPs and, therefore, their average hydrodynamic diameter.

The Cu2+ ion plays a key role in many metabolic processes, so being able to accurately determine levels of Cu2+ is important in various aspects of biology.

The authors applied their technique to water samples and say that it is both simple and timesaving, with the potential to be extended to other bioassays in the future.

A highly sensitive sensor for Cu2+ with unmodified gold nanoparticles and DNAzyme by using the dynamic light scattering technique
Xiangmin Miao, Liansheng Ling, Du Cheng and Xintao Shuai
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35217F

This paper will be free to access until 21 June 2012.

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