Analyst Blog

Xu et al., Analyst, 2012, Advance Article

Imagine analyzing a single nanoparticle? That’s what Xiao-Hong Nancy Xu and her co-workers in the USA at Old Dominion University have been doing. They have development a single-NP plasmonic microscopy and spectroscopy and ultrasensitive in vivo assay which they are using to study transport and toxicity of single silver nanoparticles on embryonic development.

Single nanoparticle spectroscopy for real-time in vivo quantitative analysis of transport and toxicity of single nanoparticles in single embryos
Kerry J. Lee, Prakash D. Nallathamby, Lauren M. Browning, Tanvi Desai, Pavan K. Cherukuri and Xiao-Hong Nancy Xu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35293A

Paul S. Francis from Deakin University, Australia, and colleagues from Australia and the USA have studied osmium complexes that contain phenanthroline, diphosphine and diarsine ligands and assessed their potential as chemiluminescence reagents. Osmium complexes do have some advantages over their ruthenium counterparts. The larger crystal field strength of the heavy metal raises the energy of the non-emissive d–d states. This in turn reduces thermal deactivation of the metal-to-ligand charge transfer (MLCT) states, creating greater photostability.

Francis et al., Analyst, 2012, Advance Article

Click here to read more about these interesting complexes.

Chemiluminescence from osmium(II) complexes with phenanthroline, diphosphine and diarsine ligands
Elizabeth M. Zammit, Gregory J. Barbante, Brenden Carlson, Egan H. Doeven, Neil W. Barnett, Conor F. Hogan, Mark M. Richter and Paul S. Francis
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35446B

Currivan, Connolly and Paull, Analyst, 2012,137, 2559-2566

What’s HOT in the latest issue of Analyst?  The selection of articles includes solution-based nano-plasmonic sensing, a new multi-mode stationary phase for liquid chromatography, immunoarrays, and nucleic acid detection.  There’s also a paper on novel polymer monolithic columns by Brett Paull, Editor-in-Chief of our sister journal, Analytical Methods.

Don’t forget to find out more about this issue’s cover articles too.

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A new biosensor that uses a target-induced DNAzyme cascade with catalytic and molecular beacons (CAMB) to fluorescently detect mercury(II) ions in water has been designed by a team from China. Yongxi Zhao from Xi’an Jiaotong University and colleagues tested the biosensor on river water samples with satisfactory results. Click on the title below to read more.

Amplified fluorescence detection of mercury(II) ions (Hg²⁺) using target-induced DNAzyme cascade with catalytic and molecular beacons
Lin Qi, Yongxi Zhao, Hui Yuan, Kai Bai, Yue Zhao, Feng Chen, Yanhua Dong and Yayan Wu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35437C

It’s been a busy month with so many great papers, so here are some HOT articles from Analyst that you might have missed this April!

Why not take a look, they will be free to read for 2 weeks.

Analysis of immunoarrays using a gold grating-based dual mode surface plasmon-coupled emission (SPCE) sensor chip
Jong Seol Yuk, George N. Gibson, James M. Rice, Ernest F. Guignon and Michael A. Lynes
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35143A

Selective recognition of xylene isomers using ZnO–SWNTs hybrid gas sensors
S. C. Hernández, C. M. Hangarter, A. Mulchandani and N. V. Myung
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35168D

Time-dependent nanogel aggregation for naked-eye assays of α-amylase activity
Hui Jiang and Xuemei Wang
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN00038E

Fast and sensitive dye-sensor based on fluorescein/reduced graphene oxide complex
Sheng Tian Huang ,  Yan Shi ,  Nian Bing Li and Hong Qun Luo
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35099H

New poly(ionic liquid)-grafted silica multi-mode stationary phase for anion-exchange/reversed-phase/hydrophilic interaction liquid chromatography
Hongdeng Qiu, Abul K. Mallik, Makoto Takafuji, Shengxiang Jiang and Hirotaka Ihara
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35348B

An electrochemical thermometer: voltammetric measurement of temperature and its application to amperometric gas sensing
Linhongjia Xiong, Ai M. Fletcher, Sven Ernst, Stephen G. Davies and Richard G. Compton
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35336A

A fluorous synthetic receptor that recognizes perfluorooctanoic acid (PFOA) via fluorous interaction obtained by molecular imprinting
Megumi Takayose,  Kenji Nishimoto and Jun Matsui
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN15936H

Detection of DNA based on fluorescence resonance energy transfer of polyelectrolyte-protected CdTe quantum dots as energy donors
Ting Qiu, Bin Zhang, Zi-yang Hu, Jian-hua Tang, Hong-ping Xie and Bing-ren Gu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35229J

DNA-templated silver nanoclusters–graphene oxide nanohybrid materials: a platform for label-free and sensitive fluorescence turn-on detection of multiple nucleic acid targets
Yu Tao, Youhui Lin, Zhenzhen Huang, Jinsong Ren and Xiaogang Qu
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35373C

A hyphenated optical trap capillary electrophoresis laser induced native fluorescence system for single-cell chemical analysis
Christine Cecala, Stanislav S. Rubakhin, Jennifer W. Mitchell, Martha U. Gillette and Jonathan V. Sweedler
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35198F

Production of novel polymer monolithic columns, with stationary phase gradients, using cyclic olefin co-polymer (COC) optical filters
Sinéad Currivan,  Damian Connolly and Brett Paull
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35316D