It’s hot hot hot in the latest issue of Analyst, with 14 HOT articles featuring the best in analytical science. Including: a review on the detection of α-amino-β-methylaminopropionic acid, mid-IR spectroscopy for salivary calculi, fluorescent chemosensing of Ag+, and an artificial nose.
Archive for April, 2012
Analyst Issue 9: now online
The latest issue of Analyst is now available for you to browse, and we head east for all three covers.
There’s nanoparticle-assisted laser desorption/ionisation MS from Japan, electrochemical biosensing from Korea, and microextraction from Taiwan.
Symposium on Advances in Raman Spectroscopy in Pharmaceutical Analysis – Registration now open!
FACSS in conjunction with JPAG, RSC MSG & the IRDG present a Joint Symposium
on “Advances in Raman Spectroscopy in Pharmaceutical Analysis” on 17 May 2012: London, UK.
Registration is now open!
Jointly organised with: Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), the Joint Pharmaceutical Analysis Group (JPAG), the Royal Society of Chemistry Molecular Spectroscopy Group (MSG) and the Infrared & Raman Discussion Group (IRDG).
Raman spectroscopy has found favor in pharmaceutical analysis because it is nondestructive, requires minimal sample preparation, and gives clear spectra for identification. This 1-day symposium demonstrates a breadth of successful Raman applications spanning the R&D field, API development, scale-up, and manufacturing, as well as drug product formulation development, characterization, and product assay. Poster presentations, a student prize, and an exhibition of Raman instruments add to the value of the symposium.
Additional information about this symposium is available here.
This meeting represents one of the first “FACSS present” events. FACSS participation in this meeting is in support of several of the member organizations of FACSS and the charter of FACSS.
Programme topics include:
• The use of Raman in characterising amorphous and crystalline forms of APIs
• Moving PAT from laboratory to production and getting FDA approval
• Raman spectral imaging to characterise individual particles
• Removing the effects of packaging to identify raw materials with Spatially Offset Raman Spectroscopy [SORS]
• Reverse engineering studies with Raman imaging to defend patents
• Why transmission Raman spectroscopy is the future: case studies
• Comparison of NIR, Raman backscattering and transmission spectroscopy for the analysis of polymorphs
• Laboratory vs hand-held instruments: what you gain and what you lose
• Vendors’ showcase exhibition
HOT Article: Electrochemical determination of glutathione
In this HOT review paper, Richard Compton and co-workers from Oxford University discuss the importance of glutathione determination, which has been shown to have physiological importance in diseases such as Parkinson’s, diabetes and cancer. Because of its medical significance, it is important to have quick and easy assays to aid clinical diagnostics and treatment. Click here to read more!
Electrochemical determination of glutathione: a review
John C. Harfield, Christopher Batchelor-McAuley and Richard G. Compton
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35090D
HOT Article: Solvation-based screening for metabolite arrays
In this HOT paper Seetharaman Vaidyanathan and colleagues from the University of Sheffield explore a new method for screening metabolites based on an array format, using relative polarity and selective solvent dissolution. This approach has the potential to be a successful way of rapidly screening metabolomes and it will allow the simultaneous screening and profiling of multiple samples.
A solvation-based screening approach for metabolite arrays
Malinda Salim, Phillip C. Wright and Seetharaman Vaidyanathan
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN16318G
HOT Article: Real time separation of natural products
In this HOT paper Patrick Giraudeau, from the Université de Nantes and colleagues, shows the first implementation of an on-line ultrafast HPLC-NMR. Ultrafast COSY spectra were recorded every 12 s in the course of a chromatographic run performed on a mixture of natural aromatic compounds. Click through here to read more!
Real-time separation of natural products by ultrafast 2D NMR coupled to on-line HPLC
Luiz H. K. Queiroz Júnior, Darlene P. K. Queiroz, Liene Dhooghe, Antonio G. Ferreira and Patrick Giraudeau
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN16208C