In this HOT paper Patrick Giraudeau, from the Université de Nantes and colleagues, shows the first implementation of an on-line ultrafast HPLC-NMR. Ultrafast COSY spectra were recorded every 12 s in the course of a chromatographic run performed on a mixture of natural aromatic compounds. Click through here to read more!
Real-time separation of natural products by ultrafast 2D NMR coupled to on-line HPLC
Luiz H. K. Queiroz Júnior, Darlene P. K. Queiroz, Liene Dhooghe, Antonio G. Ferreira and Patrick Giraudeau
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN16208C